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  1. 1.   Arrow pushing in RNA modification sequencing
  2. Bartee,David; Thalalla Gamage,Supuni; Link,Courtney; Meier,Jordan
  3. Chemical Society reviews. 2021, Jul 14;
  1. 2.   SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations
  2. Liao, Tsung-Jen; Jang,Hyunbum; Fushman, David; Nussinov,Ruth
  3. The Journal of chemical physics. 2020, Jul 28; 153(4): 045106.
  1. 3.   Chemical Modulation of Pre-mRNA Splicing in Mammalian Systems
  2. Boer, Robert E.; Torrey, Zachary R.; Schneekloth,Jay
  3. ACS CHEMICAL BIOLOGY. 2020, Apr 17; 15(4): 808-818.
  1. 4.   High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1
  2. Liao,Tsung-Jen; Jang,Hyunbum; Nussinov,Ruth; Fushman, David
  3. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2020, Feb 19; 142: 3401-3411.
  1. 5.   Specific RITA modification produces hyperselective cytotoxicity while maintaining in vivo antitumor efficacy
  2. Peyser,Brian; Hermone,Ann; Salamoun, Joseph M; Burnett, James C; Hollingshead,Melinda; McGrath,Connor; Gussio,Rick; Wipf, Peter
  3. Molecular cancer therapeutics. 2019, OCT; 18(10): 1765-1774.
  1. 6.   New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model
  2. Konstantinovic, Jelena; Kiris, Erkan; Kota, Krishna P.; Kugelman-Tonos, Johanny; Videnovic, Milica; Cazares, Lisa H.; Jovanovic, Natasa Terzic; Verbic, Tatjana Z.; Andjelkoyic, Boban; Duplantier, Allen J.; Bavari, Sina; Solaja, Bogdan A.
  3. Journal of Medicinal Chemistry. 2018, Feb 22; 61(4): 1595-1608.
  1. 7.   A Small-Molecule Microarray Approach for the Identification of E2 Enzyme Inhibitors in Ubiquitin-Like Conjugation Pathways
  2. Zlotkowski, Katherine; Hewitt, Will; Sinniah, Ranu S; Tropea, Joseph; Needle, Danielle; Lountos, George; Barchi, Joe; Waugh, David; Schneekloth, Jay
  3. SLAS Discovery. 2017, Jul; 22(6): 760-766.
  1. 8.   High-throughput single-molecule screen for small-molecule perturbation of splicing and transcription kinetics
  2. Day, C. R.; Chen, H.; Coulon, A.; Meier, J. L.; Larson, D. R.
  3. Methods (San Diego, Calif.). 2016, 1-Mar; 96: 59-68.
  1. 9.   Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents
  2. Devkota, L.; Lin, C. M.; Strecker, T. E.; Wang, Y.; Tidmore, J. K.; Chen, Z.; Guddneppanavar, R.; Jelinek, C. J.; Lopez, R.; Liu, L.; Hamel, E.; Mason, R. P.; Chaplin, D. J.; Trawick, M. L.; Pinney, K. G.
  3. Bioorganic & Medicinal Chemistry. 2016, 1-Mar; 24(5): 938-56.
  1. 10.   Antitumor Activity of a Novel Oncrasin Analogue Is Mediated by JNK Activation and STAT3 Inhibition
  2. Guo, W.; Wu, S. H.; Wang, L.; Wei, X. L.; Liu, X. Y.; Wang, J.; Lu, Z. M.; Hollingshead, M.; Fang, B. L.
  3. Plos One. 2011, Dec; 6(12):
  1. 11.   Investigation of Unanticipated Alkylation at the N(pi) Position of a Histidyl Residue Under Mitsunobu Conditions and Synthesis of Orthogonally Protected Histidine Analogues
  2. Qian, W. J.; Liu, F.; Burke, T. R.
  3. Journal of Organic Chemistry. 2011, Nov; 76(21): 8885-8890.
  1. 12.   RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
  2. Lipkowitz, S.; Weissman, A. M.
  3. Nature Reviews Cancer. 2011, Sep; 11(9): 629-643.
  1. 13.   Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel
  2. Liu, F.; Park, J. E.; Qian, W. J.; Lim, D.; Graber, M.; Berg, T.; Yaffe, M. B.; Lee, K. S.; Burke, T. R.
  3. Nature Chemical Biology. 2011, Sep; 7(9): 595-601.
  1. 14.   A Dual-Readout F(2) Assay That Combines Fluorescence Resonance Energy Transfer and Fluorescence Polarization for Monitoring Bimolecular Interactions
  2. Du, Y. H.; Nikolovska-Coleska, Z.; Qui, M.; Li, L.; Lewis, I.; Dingledine, R.; Stuckey, J. A.; Krajewski, K.; Roller, P. P.; Wang, S. M.; Fu, H. A.
  3. Assay and Drug Development Technologies. 2011, Aug; 9(4): 382-393.
  1. 15.   Synthesis, Activity, and Structural Analysis of Novel alpha-Hydroxytropolone Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H
  2. Chung, S. M.; Himmel, D. M.; Jiang, J. K.; Wojtak, K.; Bauman, J. D.; Rausch, J. W.; Wilson, J. A.; Beutler, J. A.; Thomas, C. J.; Arnold, E.; Le Grice, S. F. J.
  3. Journal of Medicinal Chemistry. 2011, Jul; 54(13): 4462-4473.
  1. 16.   Identification of Four Potential Epigenetic Modulators from the NCI Structural Diversity Library Using a Cell-Based Assay
  2. Best, A. M.; Chang, J. J.; Dull, A. B.; Beutler, J. A.; Martinez, E. D.
  3. Journal of Biomedicine and Biotechnology. 2011 11.
  1. 17.   Conformational ensembles, signal transduction and residue hot spots: Application to drug discovery
  2. Ozbabacan, S. E. A.; Gursoy, A.; Keskin, O.; Nussinov, R.
  3. Current Opinion in Drug Discovery & Development. 2010, Sep; 13(5): 527-537.
  1. 18.   Iterative Structure-Based Peptide-Like Inhibitor Design against the Botulinum Neurotoxin Serotype A
  2. Zuniga, J. E.; Hammill, J. T.; Drory, O.; Nuss, J. E.; Burnett, J. C.; Gussio, R.; Wipf, P.; Bavari, S.; Brunger, A. T.
  3. Plos One. 2010, Jun; 5(6): 15.
  1. 19.   12 Arylstibonic acids that inhibit the DNA binding of five B-ZIP dimers
  2. Rishi, V.; Oh, W. J.; Heyerdahl, S. L.; Zhao, J. F.; Scudiero, D.; Shoemaker, R. H.; Vinson, C.
  3. Journal of Structural Biology. 2010, May; 170(2): 216-225.
  1. 20.   Novel approaches to inhibiting HIV-1 replication
  2. Adamson, C. S.; Freed, E. O.
  3. Antiviral Research. 2010, Jan; 85(1): 119-141.
  1. 21.   Directed Discovery of Agents Targeting the Met Tyrosine Kinase Domain by Virtual Screening
  2. Peach, M. L.; Tan, N.; Choyke, S. J.; Giubellino, A.; Athauda, G.; Burke, T. R.; Nicklaus, M. C.; Bottaro, D. P.
  3. Journal of Medicinal Chemistry. 2009 52(4): 943-951.
  1. 22.   SYNTHESIS AND BIOLOGICAL EVALUATION OF INHIBITORS OF BOTULINUM NEUROTOXIN METALLOPROTEASE
  2. Wang, C. B.; Widom, J.; Petronijevic, F.; Burnett, J. C.; Nuss, J. E.; Bavari, S.; Gussio, R.; Wipf, P.
  3. Heterocycles. 2009 79: 487-520.
  1. 23.   Targeting the ubiquitin-proteasome system for cancer therapy
  2. Yang, Y. L.; Kitagaki, J.; Wang, H.; Hou, D. X.; Perantoni, A. O.
  3. Cancer Science. 2009 100(1): 24-28.
  1. 24.   Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53
  2. Clement, J. A.; Kitagaki, J.; Yang, Y.; Saucedo, C. J.; O'Keefe, B. R.; Weissman, A. M.; Mckee, T. C.; McMahon, J. B.
  3. Bioorganic & Medicinal Chemistry. 2008 16(23): 10022-10028.
  1. 25.   Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids
  2. Seiple, L. A.; Cardellina, J. H.; Akee, R.; Stivers, J. T.
  3. Molecular Pharmacology. 2008 73(3): 669-677.
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