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  1. 1.   Highlights of 10 years of immunology in Nature Reviews Immunology
  2. Medzhitov, R.; Shevach, E. M.; Trinchieri, G.; Mellor, A. L.; Munn, D. H.; Gordon, S.; Libby, P.; Hansson, G. K.; Shortman, K.; Dong, C.; Gabrilovich, D.; Gabrysova, L.; Howes, A.; O'Garra, A.
  3. Nature Reviews Immunology. 2011, Oct; 11(10): 693-702.
  1. 2.   Therapeutic modulation of Akt activity and antitumor efficacy of interleukin-12 against orthotopic murine neuroblastoma
  2. Khan, T.; Hixon, J. A.; Stauffer, J. K.; Lincoln, E.; Back, T. C.; Brenner, J.; Lockett, S.; Nagashima, K.; Powell, D.; Wigginton, J. M.
  3. Journal of the National Cancer Institute. 2006, FEB 1; 98(3): 190-202.
  1. 3.   Structure and characterization of hamster IL-12 p35 and p40
  2. Maruyama, K.; Takigawa, Y.; Akiyama, Y.; Hojo, T.; Nara-Ashizawa, N.; Cheng, J. Y.; Watanabe, M.; Yamaguchi, K.
  3. Molecular Immunology. 2003 40(6): 319-326.
  1. 4.   IL-2 and IL-12 alter NK cell responsiveness to IFN-gamma- inducible protein 10 by down-regulating CXCR3 expression
  2. Hodge, D. L.; Schill, W. B.; Wang, J. M.; Blanca, I.; Reynolds, D. A.; Ortaldo, J. R.; Young, H. A.
  3. Journal of Immunology. 2002 168(12): 6090-6098.
  1. 5.   Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control
  2. Hodge, D. L.; Martinez, A.; Julias, J. G.; Taylor, L. S.; Young, H. A.
  3. Molecular and Cellular Biology. 2002 22(6): 1742-1753.
  1. 6.   IL-12/IL-2 combination cytokine therapy for solid tumours: translation from bench to bedside
  2. Wigginton, J. M.; Wiltrout, R. H.
  3. Expert Opinion on Biological Therapy. 2002 2(5): 513-524.
  1. 7.   IFN-gamma and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy
  2. Wigginton, J. M.; Gruys, E.; Geiselhart, L.; Subleski, J.; Komschlies, K. L.; Park, J. W.; Wiltrout, T. A.; Nagashima, K.; Back, T. C.; Wiltrout, R. H.
  3. Journal of Clinical Investigation. 2001 108(1): 51-62.
  1. 8.   Intradermal delivery of IL-12 naked DNA induces systemic NK cell activation and Th1 response in vivo that is independent of endogenous IL-12 production
  2. Watanabe, M.; Fenton, R. G.; Wigginton, J. M.; McCormick, K. L.; Volker, K. F.; Fogler, W. E.; Roessler, P. G.; Wiltrout, R. H.
  3. Journal of Immunology. 1999 163(4): 1943-1950.
  1. 9.   Characterization of Cytokine Differential Induction of Stat Complexes in Primary Human T and Nk Cells
  2. Yu, C. R.; Young, H. A.; Ortaldo, J. R.
  3. Journal of Leukocyte Biology. 1998 64(2): 245-258.
  1. 10.   T Cell- and Nk Cell-Independent Inhibition of Hepatic Metastases By Systemic Administration of an Il-12-Expressing Recombinant Adenovirus
  2. Siders, W. M.; Wright, P. W.; Hixon, J. A.; Alvord, W. G.; Back, T. C.; Wiltrout, R. H.; Fenton, R. G.
  3. Journal of Immunology. 1998 160(11): 5465-5474.
  1. 11.   Recruitment of hepatic NK cells by IL-12 is dependent on IFN-gamma and VCAM-1 and is rapidly down-regulated by a mechanism involving T cells and expression of fas
  2. Fogler, W. E.; Volker, K.; Watanabe, M.; Wigginton, J. M.; Roessler, P.; Brunda, M. J.; Ortaldo, J. R.; Wiltrout, R. H.
  3. Journal of Immunology. 1998 161(11): 6014-6021.
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