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  1. 1.   Gene-specific transcription activation via long-range allosteric shape-shifting
  2. Tsai, C. J.; Nussinov, R.
  3. Biochemical Journal. 2011, Oct; 439: 15-25.
  1. 2.   Lysine120 Interactions with p53 Response Elements can Allosterically Direct p53 Organization
  2. Pan, Y. P.; Nussinov, R.
  3. Plos Computational Biology. 2010, Aug; 6(8): e1000878.
  1. 3.   Mechanisms of transcription factor selectivity
  2. Pan, Y. P.; Tsai, C. J.; Ma, B. Y.; Nussinov, R.
  3. Trends in Genetics. 2010, Feb; 26(2): 75-83.
  1. 4.   Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation
  2. Huang, J.; Chen, K. Q.; Huang, J. Q.; Gong, W. H.; Dunlop, N. M.; Howard, O.; Bian, X. W.; Gao, Y. Q.; Wang, J. M.
  3. Carcinogenesis. 2009 30(2): 348-355.
  1. 5.   Computer Simulations of Peptides from the p53 DNA Binding Domain
  2. Khalili, M.; Wales, D. J.
  3. Journal of Chemical Theory and Computation. 2009 5(5): 1380-1392.
  1. 6.   Cooperativity Dominates the Genomic Organization of p53-Response Elements: A Mechanistic View
  2. Pan, Y. P.; Nussinov, R.
  3. Plos Computational Biology. 2009 5(7):
  1. 7.   Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis
  2. Hu, C. A. A.; Donald, S. P.; Yu, J.; Lin, W. W.; Liu, Z. H.; Steel, G.; Obie, C.; Valle, D.; Phang, J. M.
  3. Molecular and Cellular Biochemistry. 2007, Jan; 295(1-2): 85-92.
  1. 8.   In the quest for stable rescuing mutants of p53: Computational mutagenesis of flexible loop L1
  2. Pan, Y. P.; Ma, B. Y.; Venkataraghavan, R. B.; Levine, A. J.; Nussinov, R.
  3. Biochemistry. 2005, FEB 8; 44(5): 1423-1432.
  1. 9.   Assay for ubiquitin ligase activity: High-throughput screen for inhibitors of HDM2
  2. Davydov, I. V.; Woods, D.; Safiran, Y. J.; Oberoi, P.; Fearnhead, H. O.; Fang, S.; Jensen, J. P.; Weissman, A. M.; Kenten, J. H.; Vousden, K. H.
  3. Journal of Biomolecular Screening. 2004, DEC; 9(8): 695-703.
  1. 10.   Regulation of HDM2 activity by the ribosomal protein L11
  2. Lohrum, M. A. E.; Ludwig, R. L.; Kubbutat, M. H. G.; Hanlon, M.; Vousden, K. H.
  3. Cancer Cell. 2003 3(6): 577-587.
  1. 11.   Regulation of p53 function
  2. Woods, D. B.; Vousden, K. H.
  3. Experimental Cell Research. 2001 264(1): 56-66.
  1. 12.   Inhibition of HIF-1-and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions
  2. Blagosklonny, M. V.; Giannakakou, P.; Romanova, L. Y.; Ryan, K. M.; Vousden, K. H.; Fojo, T.
  3. Carcinogenesis. 2001 22(6): 861-867.
  1. 13.   C-terminal ubiquitination of p53 contributes to nuclear export
  2. Lohrum, M. A. E.; Woods, D. B.; Ludwig, R. L.; Balint, E.; Vousden, K. H.
  3. Molecular and Cellular Biology. 2001 21(24): 8521-8532.
  1. 14.   Stress signals utilize multiple pathways to stabilize p53
  2. Ashcroft, M.; Taya, Y.; Vousden, K. H.
  3. Molecular and Cellular Biology. 2000 20(9): 3224-3233.
  1. 15.   Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
  2. Fang, S. Y.; Jensen, J. P.; Ludwig, R. L.; Vousden, K. H.; Weissman, A. M.
  3. Journal of Biological Chemistry. 2000 275(12): 8945-8951.
  1. 16.   Regulation of p53 stability
  2. Ashcroft, M.; Vousden, K. H.
  3. Oncogene. 1999 18(53): 7637-7643.
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