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  1. 1.   Effects of malleable kinetochore morphology on measurements of intrakinetochore tension
  2. Renda, Fioranna; Magidson,Valentin; Tikhonenko, Irina; Fisher, Rebecca; Miles, Christopher; Mogilner, Alex; Khodjakov, Alexey
  3. OPEN BIOLOGY. 2020, JUL 8; 10(7):
  1. 2.   The Development and Characterization of a Human Mesothelioma In Vitro 3D Model to Investigate Immunotoxin Therapy
  2. Xiang, X. R.; Phung, Y.; Feng, M. Q.; Nagashima, K.; Zhang, J. L.; Broaddus, V. C.; Hassan, R.; FitzGerald, D.; Ho, M.
  3. Plos One. 2011, Jan; 6(1): 10.
  1. 3.   Design and synthesis of paclitaxel conjugated with an ErbB2-Recognizing pepticle, EC-1
  2. Li, P.; Jiang, S.; Pero, S. C.; Oligino, L.; Krag, D. N.; Michejda, C. J.; Roller, P. P.
  3. Biopolymers. 2007, Nov; 87(4): 225-230.
  1. 4.   In vitro efficacy of immuno-chemotherapy with anti-EGFR human fab-taxol conjugate on A431 epidermoid carcinoma cells
  2. Wang, X.; Zhu, J.; Zhao, P.; Jiao, Y. G.; Xu, N.; Grabinski, T.; Liu, C.; Miranti, C. K.; Fu, T.; Cao, B. B.
  3. Cancer Biology & Therapy. 2007, Jun; 6(6): 980-986.
  1. 5.   Taxoids: Cancer-fighting compounds from nature
  2. Kingston, D. G. I.; Newman, D. J.
  3. Current Opinion in Drug Discovery & Development. 2007, Mar; 10(2): 130-144.
  1. 6.   Synergistic effects of peloruside a and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly
  2. Hamel, E.; Day, B. W.; Miller, J. H.; Jung, M. K.; Northcote, P. T.; Ghosh, A. K.; Curran, D. P.; Cushman, M.; Nicolaou, K. C.; Paterson, I.; Sorensen, E. J.
  3. Molecular Pharmacology. 2006, Nov; 70(5): 1555-1564.
  1. 7.   Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin
  2. Madiraju, C.; Edler, M. C.; Hamel, E.; Raccor, B. S.; Balachandran, R.; Zhu, G. Y.; Giuliano, K. A.; Vogt, A.; Shin, Y. S.; Fournier, J. H.; Fukui, Y. H.; Bruckner, A. M.; Curran, D. P.; Day, B. W.
  3. Biochemistry. 2005, NOV 15; 44(45): 15053-15063.
  1. 8.   Synthesis and biological evaluation of (-)-16-normethyldictyostatin: A potent analogue of (-)-dictyostatin
  2. Shin, Y.; Fournier, J. H.; Balachandran, R.; Madiraju, C.; Raccor, B. S.; Zhu, G.; Edler, M. C.; Hamel, E.; Day, B. W.; Curran, D. P.
  3. Organic Letters. 2005, JUL 7; 7(14): 2873-2876.
  1. 9.   A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel
  2. Dabydeen, D. A.; Florence, G. J.; Paterson, I.; Hamel, E.
  3. Cancer Chemotherapy and Pharmacology. 2004 53(5): 397-403.
  1. 10.   A tale of two tumor targets: Topoisomerase I and tubulin. The Wall and Wani contribution to cancer chemotherapy
  2. Cragg, G. M.; Newman, D. J.
  3. Journal of Natural Products. 2004 67(2): 232-244.
  1. 11.   The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity
  2. Pryor, D. E.; O'Brate, A.; Bilcer, G.; Diaz, J. F.; Wang, Y. F.; Wang, Y.; Kabaki, M.; Jung, M. K.; Andreu, J. M.; Ghosh, A. K.; Giannakakou, P.; Hamel, E.
  3. Biochemistry. 2002 41(29): 9109-9115.
  1. 12.   Relating molecular flexibility to function: A case study of tubulin
  2. Keskin, O.; Durell, S. R.; Bahar, I.; Jernigan, R. L.; Covell, D. G.
  3. Biophysical Journal. 2002 83(2): 663-680.
  1. 13.   Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests
  2. Mi, Q. W.; Lantvit, D.; Reyes-Lim, E.; Chai, H. Y.; Zhao, W. M.; Lee, I. S.; Peraza-Sanchez, S.; Ngassapa, O.; Kardono, L. B. S.; Riswan, S.; Hollingshead, M. G.; Mayo, J. G.; Farnsworth, N. R.; Cordell, G. A.; Kinghorn, A. D.; Pezzuto, J. M.
  3. Journal of Natural Products. 2002 65(6): 842-850.
  1. 14.   The separation of a penicillium fungal extract by thin layer chromatography and HPLC: A comparative study
  2. Xu, H. Y.; Issaq, S. H.; McCloud, T. G.; Issaq, H. J.
  3. Journal of Liquid Chromatography & Related Technologies. 2001 24(5): 625-633.
  1. 15.   Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes
  2. Abraham, E. H.; Shrivastav, B.; Salikhova, A. Y.; Sterling, K. M.; Johnston, N.; Guidotti, G.; Scala, S.; Litman, T.; Chan, K. C.; Arceci, R. J.; Steiglitz, K.; Herscher, L.; Okunieff, P.
  3. Blood Cells Molecules and Diseases. 2001, JAN-FEB; 27(1): 181-200.
  1. 16.   Expression of beta-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-anticancer drug screen: Correlation with sensitivity to microtubule active agents
  2. Nicoletti, M. I.; Valoti, G.; Giannakakou, P.; Zhan, Z. R.; Kim, J. H.; Lucchini, V.; Landoni, F.; Mayo, J. G.; Giavazzi, R.; Fojo, T.
  3. Clinical Cancer Research. 2001 7(9): 2912-2922.
  1. 17.   Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-x(L) protein levels
  2. Tudor, G.; Aguilera, A.; Halverson, D. O.; Laing, N. D.; Sausville, E. A.
  3. Cell Death and Differentiation. 2000 7(6): 574-586.
  1. 18.   A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells
  2. Giannakakou, P.; Gussio, R.; Nogales, E.; Downing, K. H.; Zaharevitz, D.; Bollbuck, B.; Poy, G.; Sackett, D.; Nicolaou, K. C.; Fojo, T.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2000 97(6): 2904-2909.
  1. 19.   A steroid derivative with paclitaxel-like effects on tubulin polymerization
  2. Verdier-Pinard, P.; Wang, Z. Q.; Mohanakrishnan, A. K.; Cushman, M.; Hamel, E.
  3. Molecular Pharmacology. 2000 57(3): 568-575.
  1. 20.   Synthesis and biological activity of a novel C4-C6 bridged paclitaxel analog
  2. Yuan, H. Q.; Kingston, D. G. I.; Sackett, D. L.; Hamel, E.
  3. Tetrahedron. 1999 55(32): 9707-9716.
  1. 21.   The coral-derived natural products eleutherobin and sarcodictyins A and B: Effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site
  2. Hamel, E.; Sackett, D. L.; Vourloumis, D.; Nicolaou, K. C.
  3. Biochemistry. 1999 38(17): 5490-5498.
  1. 22.   Synthesis and Biological Activity of a-Nor-Paclitaxel Analogues
  2. Chordia, M. D.; Kingston, D. G. I.; Hamel, E.; Lin, C. M.; Long, B. H.; Fairchild, C. A.; Johnston, K. A.; Rose, W. C.
  3. Bioorganic & Medicinal Chemistry. 1997 5(5): 941-947.
  1. 23.   Resistance to Paclitaxel Mediated By P-Glycoprotein Can Be Modulated By Changes in the Schedule of Administration
  2. Zhan, A. R.; Scala, S.; Monks, A.; Hose, C.; Bates, S.; Fojo, T.
  3. Cancer Chemotherapy and Pharmacology. 1997 40(3): 245-250.
  1. 24.   Synthesis of Epothilones a and B in Solid and Solution Phase
  2. Nicolaou, K. C.; Winssinger, N.; Pastor, J.; Ninkovic, S.; Sarabia, F.; He, Y.; Vourloumis, D.; Yang, Z.; Li, T.; Giannakakou, P.; Hamel, E.
  3. Nature. 1997 387(6630): 268-272.
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