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  1. 1.   Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b] thiophene derivatives as potent apoptosis-inducing agents
  2. Romagnoli, Romeo; Preti, Delia; Hamel,Ernest; Bortolozzi, Roberta; Viola, Giampietro; Brancale, Andrea; Ferla, Salvatore; Morciano, Giampaolo; Pinton, Paolo
  3. Bioorganic chemistry. 2021, Jul; 112
  1. 2.   Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives
  2. Romagnoli, R.; Baraldi, P. G.; Cruz-Lopez, O.; Tolomeo, M.; Di Cristina, A.; Pipitone, R. M.; Grimaudo, S.; Balzarini, J.; Brancale, A.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry Letters. 2011, May; 21(9): 2746-2751.
  1. 3.   Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents
  2. Romagnoli, R.; Baraldi, P. G.; Cara, C. L.; Hamel, E.; Basso, G.; Bortolozzi, R.; Viola, G.
  3. European Journal of Medicinal Chemistry. 2010, Dec; 45(12): 5781-5791.
  1. 4.   Synthesis and Cellular Pharmacology Studies of a Series of 2-amino-3-aroyl-4-substituted Thiophene Derivatives
  2. Romagnoli, R.; Baraldi, P. G.; Pavani, M. G.; Cruz-Lopez, O.; Hamel, E.; Balzarini, J.; Brognara, E.; Zuccato, C.; Gambari, R.
  3. Medicinal Chemistry. 2010, Nov; 6(6): 329-343.
  1. 5.   Synthesis and Evaluation of Haloacetyl, alpha-Bromoacryloyl and Nitrooxyacetyl Benzo[b]furan and Benzo[b]thiophene Derivatives as Potent Antiproliferative Agents Against Leukemia L1210 and K562 Cells
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cara, C. L.; Casolari, A.; Hamel, E.; Fabbri, E.; Gambari, R.
  3. Letters in Drug Design & Discovery. 2010, Aug; 7(7): 476-486.
  1. 6.   Synthesis and biological evaluation of 2-amino-3-(3 ',4 ',5 '-trimethoxyphenyisulfonyl)-5-aryl thiophenes as a new class of antitubulin agents
  2. Romagnoli, R.; Baraldi, P. G.; Remusat, V.; Carrion, M. D.; Cara, C. L.; Cruz-Lopez, O.; Preti, D.; Fruttarolo, F.; Tabrizi, M. A.; Balzarini, J.; Hamel, E.
  3. Medicinal Chemistry. 2007, Nov; 3(6): 507-512.
  1. 7.   Synthesis and biological evaluation of 2-and 3-aminobenzo b thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cara, C. L.; Preti, D.; Fruttarolo, F.; Pavani, M. G.; Tabrizi, M. A.; Tolomeo, M.; Grimaudo, S.; Di Cristina, A.; Balzarini, J.; Hadfield, J. A.; Brancale, A.; Hamel, E.
  3. Journal of Medicinal Chemistry. 2007, May; 50(9): 2273-2277.
  1. 8.   A novel palladium-mediated coupling approach to 2,3- disubstituted benzo[b]thiophenes and its application to the synthesis of tubulin binding agents
  2. Flynn, B. L.; Verdier-Pinard, P.; Hamel, E.
  3. Organic Letters. 2001 3(5): 651-654.
  1. 9.   Selective toxicity of the tricyclic thiophene NSC652287 in renal carcinoma cell lines - Differential accumulation and metabolism
  2. Rivera, M. I.; Stinson, S. F.; Vistica, D. T.; Jorden, J. L.; Kenney, S.; Sausville, E. A.
  3. Biochemical Pharmacology. 1999 57(11): 1283-1295.
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