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  1. 1.   Optimized mammalian expression system for the ubiquitin E3 ligase E6AP/UBE3A
  2. Schafer,Annie; Muli,Christine; Heikal,Rehab; Dyba,Marzena; Tarasov,Sergey; Stratton, Margaret M; Strieter, Eric R; Walters,Kylie
  3. Protein Expression and Purification. 2025, Jan 09; 106661.
  1. 2.   The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A
  2. Kochen Rossi, Juan; Nuevo-Tapioles, Cristina; O'Keefe, Rachel A; Hunkeler, Moritz; Schmoker, Anna M; Fissore-O'Leary, Mercedes; Su, Wenjuan; Ahearn, Ian M; Branco, Cristina; Cheong, Hakyung; Esposito,Dom; Clotea, Ioana; Ueberheide, Beatrix; Fischer, Eric S; Philips, Mark R
  3. Cell Reports. 2024, Dec 19; 44(1): 115087.
  1. 3.   Autoinhibition of ubiquitin-specific protease 8: insights into domain interactions and mechanisms of regulation
  2. Caba, Cody; Black, Megan; Liu, Yujue; DaDalt, Ashley A; Mallare, Josh; Fan,Lixin; Harding, Rachel J; Wang, Yunxin; Vacratsis, Panayiotis O; Huang, Rui; Zhuang, Zhihao; Tong, Yufeng
  3. The Journal of Biological Chemistry. 2024, Aug 28; 107727.
  1. 4.   The Degradation of Botulinum Neurotoxin Light Chains Using PROTACs
  2. Tsai,Yien Che; Kozar, Loren; Mawi, Zo P; Ichtchenko, Konstantin; Shoemaker, Charles B; McNutt, Patrick M; Weissman,Allan
  3. International Journal of Molecular Sciences. 2024, Jul 08; 25(13):
  1. 5.   K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins
  2. Magits, Wout; Steklov, Mikhail; Jang,Hyunbum; Sewduth, Raj N; Florentin, Amir; Lechat, Benoit; Sheryazdanova, Aidana; Zhang, Mingzhen; Simicek, Michal; Prag, Gali; Nussinov,Ruth; Sablina, Anna
  3. The EMBO Journal. 2024, Jun 10;
  1. 6.   Shared and distinct mechanisms of UBA1 inactivation across different diseases
  2. Collins, Jason C; Magaziner, Samuel J; English, Maya; Hassan,Bakar; Chen,Xiang; Balanda, Nicholas; Anderson, Meghan; Lam, Athena; Fernandez-Pol, Sebastian; Kwong, Bernice; Greenberg, Peter L; Terrier, Benjamin; Likhite, Mary E; Kosmider, Olivier; Wang, Yan; Samara, Nadine L; Walters,Kylie; Beck, David B; Werner, Achim
  3. The EMBO Journal. 2024, May; 43(10): 1919-1946.
  1. 7.   SARS-CoV-2 papain-like protease (PLpro) plays multiple roles in regulating cellular proteins in the endoplasmic reticulum
  2. Yang,Mei; Mariano,Jennifer; Su, Rebecca; Smith, Christopher E; Das,Sudipto; Gill, Catherine; Andresson,Thorkell; Loncarek,Jadranka; Tsai,Yien Che; Weissman,Allan
  3. The Journal of Biological Chemistry. 2023, Dec; 299(12): 105346.
  1. 8.   Spatial Mechano-Signaling Regulation of GTPases through Non-Degradative Ubiquitination
  2. Sewduth, Raj N; Carai, Paolo; Ivanisevic, Tonci; Zhang, Mingzhen; Jang,Hyunbum; Lechat, Benoit; Van Haver, Delphi; Impens, Francis; Nussinov,Ruth; Jones, Elizabeth; Sablina, Anna
  3. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 2023, Nov 09; e2303367.
  1. 9.   1H, 15N, 13C resonance assignments for proteasome shuttle factor hHR23a
  2. Chen,Xiang; Walters,Kylie
  3. Biomolecular NMR Assignments. 2023, Oct 09;
  1. 10.   1H, 15N, 13C backbone and Cß resonance assignments for UBQLN1 UBA and UBAA domains
  2. Buel, Gwen R; Chen,Xiang; Kayode, Olumide; Cruz, Anthony; Walters,Kylie
  3. Biomolecular NMR Assignments. 2023, Apr 06;
  1. 11.   Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3? protein and represses lung cancer metastasis
  2. Chen,Zibo; Zheng, Lin; Chen, Yulong; Liu,Xiuxia; Kawakami, Masanori; Mustachio, Lisa Maria; Roszik, Jason; Ferry-Galow,Katherine; Parchment,Ralph; Liu, Xin; Andresson,Thorkell; Duncan,Gerard; Kurie, Jonathan M; Rodriguez-Canales, Jaime; Liu,Xi; Dmitrovsky,Ethan
  3. Cancer Biology & Therapy. 2022, Dec 31; 23(1): 265-280.
  1. 12.   Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
  2. Cable, Jennifer; Weber-Ban, Eilika; Clausen, Tim; Walters,Kylie; Sharon, Michal; Finley, Daniel J.; Gu, Yangnan; Hanna, John; Feng, Yue; Martens, Sascha; Simonsen, Anne; Hansen, Malene; Zhang, Hong; Goodwin, Jonathan M.; Reggio, Alessio; Chang, Chunmei; Ge, Liang; Schulman, Brenda A.; Deshaies, Raymond J.; Dikic, Ivan; Harper, J. Wade; Wertz, Ingrid E.; Thoma, Nicolas H.; Slabicki, Mikolaj; Frydman, Judith; Jakob, Ursula; David, Della C.; Bennett, Eric J.; Bertozzi, Carolyn R.; Sardana, Richa; Eapen, Vinay V.; Carra, Serena
  3. Annals of the New York Academy of Sciences. 2022, Jan;
  1. 13.   Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma
  2. Lu, Xiuxiu; Sabbasani, Venkata R.; Osei-Amponsa, Vasty; Evans, Christine N.; King, Julianna C.; Tarasov, Sergey G.; Dyba, Marzena; Das, Sudipto; Chan, King C.; Schwieters, Charles D.; Choudhari, Sulbha; Fromont, Caroline; Zhao, Yongmei; Tran, Bao; Chen, Xiang; Matsuo, Hiroshi; Andresson, Thorkell; Chari, Raj; Swenson, Rolf E.; Tarasova, Nadya I.; Walters, Kylie J.
  3. Nature Communications. 2021, Dec 16; 12(1):
  1. 14.   In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase Inhibitors
  2. Wilson,Brice; Voeller, Donna; Smith,Emily; Wamiru,Antony; Goncharova,Katya; Liu, Gang; Lipkowitz, Stanley; O'Keefe,Barry
  3. SLAS DISCOVERY. 2021, Aug 21; 26(7, SI): 870-884.
  1. 15.   Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
  2. Lun, Cheng Man; Waheed,Abdul; Majadly, Alhlam; Powell, Nicole; Freed, Eric O.
  3. mBio. 2021, Mar 16; 12(2):
  1. 16.   CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity
  2. Shrestha, Roshan L.; Rossi, Austin; Wangsa, Darawalee; Hogan, Ann K.; Zaldana, Kimberly S.; Suva, Evelyn; Chung, Yang Jo; Sanders,Chelsea; Difilippantonio,Simone; Karpova, Tatiana S.; Karim,Baktiar; Foltz, Daniel R.; Fachinetti, Daniele; Aplan, Peter D.; Ried, Thomas; Basrai, Munira A.
  3. The Journal of Cell Biology. 2021, Feb 23; 220(4):
  1. 17.   Promoterless Transposon Mutagenesis Drives Solid Cancers via Tumor Suppressor Inactivation
  2. Aiderus, Aziz; Contreras-Sandoval, Ana M; Meshey, Amanda L; Newberg, Justin Y; Ward, Jerrold M; Swing,Debbie; Copeland, Neal G; Jenkins, Nancy A; Mann, Karen M; Mann, Michael B
  3. Cancers. 2021, Jan 09; 13(2):
  1. 18.   Phosphorylation of SMURF2 by ATM exerts a negative feedback control of DNA damage response
  2. Tang, Liu-Ya; Thomas, Adam; Zhou, Ming; Zhang, Ying E
  3. The Journal of biological chemistry. 2020, Dec 25; 295(52): 18485-18493.
  1. 19.   The Role of Conformational Dynamics in the Recognition and Regulation of Ubiquitination
  2. Khago, Domarin; Fucci,Ian; Byrd,Robert
  3. Molecules (Basel, Switzerland). 2020, Dec 15; 25(24):
  1. 20.   Proteasome interaction with ubiquitinated substrates: from mechanisms to therapies
  2. Chen,Xiang; Htet, Zaw Min; Lopez-Alfonzo, Erika; Martin, Andreas; Walters,Kylie
  3. The FEBS journal. 2020, DEC 11;
  1. 21.   Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome
  2. Chen,Xiang; Dorris, Zachary; Shi,Dan; Huang, Rick K; Khant,Htet; Fox,Tara; De Val Alda,Natalia; Williams, Dewight; Zhang,Ping; Walters,Kylie
  3. Structure (London, England : 1993). 2020, NOV 3; 28(11): 1206-+.
  1. 22.   Suberitamides A-C, Aryl Alkaloids from a Pseudosuberites sp. Marine Sponge that Inhibit Cbl-b Ubiquitin Ligase Activity
  2. Kim,Chang-Kwon; Wang,Dongdong; Wilson,Brice; Saurí, Josep; Voeller, Donna; Lipkowitz, Stanley; O'Keefe,Barry; Gustafson,Kirk
  3. Marine drugs. 2020, NOV; 18(11): pii: E536.
  1. 23.   Impact of losing hRpn13 Pru or UCHL5 on proteasome clearance of ubiquitinated proteins and RA190 cytotoxicity
  2. Osei Amponsa,Vasty; Sridharan, Vinidhra; Tandon,Mayank; Evans,Christine; Klarmann,Kim; Cheng,Oscar; Lack,Justin; Chari,Raj; Walters,Kylie
  3. Molecular and cellular biology. 2020, SEP; 40(18):
  1. 24.   A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii
  2. Mandalasi, Msano; Kim, Hyun W.; Thieker, David; Sheikh, M. Osman; Gas-Pascual, Elisabet; Rahman,Kazi; Zhao, Peng; Daniel, Nitin G.; van der Wel, Hanke; Ichikawa, H. Travis; Glushka, John N.; Wells, Lance; Woods, Robert J.; Wood, Zachary A.; West, Christopher M.
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, JUL 3; 295(27): 9223-9243.
  1. 25.   An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure
  2. Lu,Xiuxiu; Ebelle, Danielle L; Matsuo,Hiroshi; Walters,Kylie
  3. Structure (London, England : 1993). 2020, May 5; 28(5): 495-506.e3.
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