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  1. 1.   Defining the Landscape of the Pauling-Corey Rippled Sheet: An Orphaned Motif Finding New Homes
  2. Raskatov, Jevgenij A.; Schneider,Joel; Nilsson, Bradley L.
  3. Accounts of chemical research. 2021, MAY 18; 54: 2488-2501.
  1. 2.   A stable immature lattice packages IP6 for HIV capsid maturation
  2. Mallery, Donna L.; Kleinpeter,Alex; Renner, Nadine; Faysal, K. M. Rifat; Novikova, Mariia; Kiss, Leo; Wilson, Miranda S. C.; Ahsan, Bilal; Ke, Zunlong; Briggs, John A. G.; Saiardi, Adolfo; Bocking, Till; Freed,Eric; James, Leo C.
  3. Science Advances. 2021, Mar 10; 7(11):
  1. 3.   Pyrrolo[2 ',3 ':3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types
  2. Spano, Virginia; Rocca, Roberta; Barreca, Marilia; Giallombardo, Daniele; Montalbano, Alessandra; Carbone, Anna; Raimondi, Maria Valeria; Gaudio, Eugenio; Bortolozzi, Roberta; Bai,Ruoli; Tassone, Pierfrancesco; Alcaro, Stefano; Hamel,Ernest; Viola, Giampietro; Bertoni, Francesco; Barraja, Paola
  3. JOURNAL OF MEDICINAL CHEMISTRY. 2020, OCT 22; 63(20): 12023-12042.
  1. 4.   Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity
  2. Khodyuk, Rejane Gonçalves Diniz; Bai,Ruoli; Hamel,Ernest; Lourenço, Estela Mariana Guimarães; Barbosa, Euzébio Guimarães; Beatriz, Adilson; Dos Santos, Edson Dos Anjos; de Lima, Dênis Pires
  3. Bioorganic chemistry. 2020, AUG; 101: 104017.
  1. 5.   Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy
  2. Pérez-Guijarro, Eva; Yang, Howard H; Araya, Romina E; El Meskini,Rajaa; Michael, Helen T; Vodnala, Suman Kumar; Marie, Kerrie L; Smith,Cari; Chin, Sung; Lam, Khiem C; Thorkelsson, Andres; Iacovelli,Anthony; Kulaga,Alan; Fon, Anyen; Michalowski, Aleksandra M; Hugo, Willy; Lo, Roger S; Restifo, Nicholas P; Sharan,Shyam; Van Dyke, Terry; Goldszmid, Romina S; Ohler,Zoe; Lee, Maxwell P; Day, Chi-Ping; Merlino, Glenn
  3. Nature medicine. 2020, Apr 13;
  1. 6.   Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques
  2. Gonzalez-Nieto, Lucas; Castro, Isabelle M; Bischof, Georg F; Shin, Young C; Ricciardi, Michael J; Bailey, Varian K; Dang, Christine M; Pedreño-Lopez, Nuria; Magnani, Diogo M; Ejima, Keisuke; Allison, David B; Gil, Hwi Min; Evans, David T; Rakasz, Eva G; Lifson,Jeffrey; Desrosiers, Ronald C; Martins, Mauricio A
  3. PLoS pathogens. 2019, Sep 30; 15(9): e1008015.
  1. 7.   Synthesis and biological evaluation of structurally diverse alpha-conformationally restricted chalcones and related analogues
  2. Maguire, Casey J.; Carlson, Graham J.; Ford, Jacob W.; Strecker, Tracy E.; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G.
  3. MedChemComm. 2019, Aug 1; 10(8): 1445-1456.
  1. 8.   Clinical decision making in the era of immunotherapy for high grade-glioma: report of four cases
  2. Ranjan, Surabhi; Quezado, Martha; Garren, Nancy; Boris, Lisa; Siegel, Christine; Lopes Abath Neto, Osorio; Theeler, Brett J; Park, Deric M; Nduom, Edjah; Zaghloul, Kareem A; Gilbert, Mark R; Wu, Jing
  3. BMC Cancer. 2018, Mar 01; 18(1): 239.
  1. 9.   CTLA-4(+)PD-1(-) Memory CD4(+) T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques
  2. McGary, Colleen S; Deleage, Claire; Harper, Justin; Micci, Luca; Ribeiro, Susan P; Paganini, Sara; Kuri-Cervantes, Leticia; Benne, Clarisse; Ryan, Emily S; Balderas, Robert; Jean, Sherrie; Easley, Kirk; Marconi, Vincent; Silvestri, Guido; Estes, Jake; Sekaly, Rafick-Pierre; Paiardini, Mirko
  3. Immunity. 2017, Oct 17; 47(4): 776-788.e5.
  1. 10.   Effects of Point Substitutions on the Structure of Toxic Alzheimer's beta-Amyloid Channels: Atomic Force Microscopy and Molecular Dynamics Simulations
  2. Connelly, L.; Jang, H.; Arce, F. T.; Ramachandran, S.; Kagan, B. L.; Nussinov, R.; Lal, R.
  3. Biochemistry. 2012, Apr; 51(14): 3031-3038.
  1. 11.   Antineoplastic Agents. 548. Synthesis of lodo- and Diiodocombstatin Phosphate Prodrugs
  2. Pettit, G. R.; Rosenberg, H. J.; Dixon, R.; Knight, J. C.; Hamel, E.; Chapuis, J. C.; Pettit, R. K.; Hogan, F.; Sumner, B.; Ain, K. B.; Trickey-Platt, B.
  3. Journal of Natural Products. 2012, Mar; 75(3): 385-393.
  1. 12.   DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid beta-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease
  2. Olkhanud, P. B.; Mughal, M.; Ayukawa, K.; Malchinkhuu, E.; Bodogai, M.; Feldman, N.; Rothman, S.; Lee, J. H.; Chigurupati, S.; Okun, E.; Nagashima, K.; Mattson, M. P.; Biragyn, A.
  3. Vaccine. 2012, Feb; 30(9): 1650-1658.
  1. 13.   One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent
  2. Romagnoli, R.; Baraldi, P. G.; Cara, C. L.; Salvador, M. K.; Bortolozzi, R.; Basso, G.; Viola, G.; Balzarini, J.; Brancale, A.; Fu, X. H.; Li, J.; Zhang, S. Z.; Hamel, E.
  3. European Journal of Medicinal Chemistry. 2011, Dec; 46(12): 6015-6024.
  1. 14.   Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties
  2. Flynn, B. L.; Gill, G. S.; Grobelny, D. W.; Chaplin, J. H.; Paul, D.; Leske, A. F.; Lavranos, T. C.; Chalmers, D. K.; Charman, S. A.; Kostewicz, E.; Shackleford, D. M.; Morizzi, J.; Hamel, E.; Jung, M. K.; Kremmidiotis, G.
  3. Journal of Medicinal Chemistry. 2011, Sep; 54(17): 6014-6027.
  1. 15.   A Single Polymorphism in HIV-1 Subtype C SP1 Is Sufficient To Confer Natural Resistance to the Maturation Inhibitor Bevirimat
  2. Lu, W. X.; Salzwedel, K.; Wang, D.; Chakravarty, S.; Freed, E. O.; Wild, C. T.; Li, F.
  3. Antimicrobial Agents and Chemotherapy. 2011, Jul; 55(7): 3324-3329.
  1. 16.   Convergent Synthesis and Biological Evaluation of 2-Amino-4-(3 ',4 ',5 '-trimethoxyphenyl)-5-aryl Thiazoles as Microtubule Targeting Agents
  2. Romagnoli, R.; Baraldi, P. G.; Brancale, A.; Ricci, A.; Hamel, E.; Bortolozzi, R.; Basso, G.; Viola, G.
  3. Journal of Medicinal Chemistry. 2011, Jul; 54(14): 5144-5153.
  1. 17.   On the Role of the SP1 Domain in HIV-1 Particle Assembly: a Molecular Switch?
  2. Datta, S. A. K. D. S. A. K.; Temeselew, L. G.; Crist, R. M.; Soheilian, F.; Kamata, A.; Mirro, J.; Harvin, D.; Nagashima, K.; Cachau, R. E.; Rein, A.
  3. Journal of Virology. 2011, May; 85(9): 4111-4121.
  1. 18.   Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives
  2. Romagnoli, R.; Baraldi, P. G.; Cruz-Lopez, O.; Tolomeo, M.; Di Cristina, A.; Pipitone, R. M.; Grimaudo, S.; Balzarini, J.; Brancale, A.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry Letters. 2011, May; 21(9): 2746-2751.
  1. 19.   HIV-1 Maturation Inhibitor Bevirimat Stabilizes the Immature Gag Lattice
  2. Keller, P. W.; Adamson, C. S.; Heymann, J. B.; Freed, E. O.; Steven, A. C.
  3. Journal of Virology. 2011, Feb; 85(4): 1420-1428.
  1. 20.   Synthesis and Cellular Pharmacology Studies of a Series of 2-amino-3-aroyl-4-substituted Thiophene Derivatives
  2. Romagnoli, R.; Baraldi, P. G.; Pavani, M. G.; Cruz-Lopez, O.; Hamel, E.; Balzarini, J.; Brognara, E.; Zuccato, C.; Gambari, R.
  3. Medicinal Chemistry. 2010, Nov; 6(6): 329-343.
  1. 21.   Substituted 2-(3 ',4 ',5 '-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cruz-Lopez, O.; Tolomeo, M.; Grimaudo, S.; Di Cristina, A.; Pipitone, M. R.; Balzarini, J.; Brancale, A.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry. 2010, Jul; 18(14): 5114-5122.
  1. 22.   Crystal Structure of the Catalytic Domain of Drosophila beta 1,4-Galactosyltransferase-7
  2. Ramakrishnan, B.; Qasba, P. K.
  3. Journal of Biological Chemistry. 2010, May; 285(20): 15619-15626.
  1. 23.   Synthesis and Antitumor Activity of 1,5-Disubstituted 1,2,4-Triazoles as Cis-Restricted Combretastatin Analogues
  2. Romagnoli, R.; Baraldi, P. G.; Cruz-Lopez, O.; Cara, C. L.; Carrion, M. D.; Brancale, A.; Hamel, E.; Chen, L. C.; Bortolozzi, R.; Basso, G.; Viola, G.
  3. Journal of Medicinal Chemistry. 2010, May; 53(10): 4248-4258.
  1. 24.   Polymorphisms in Gag spacer peptide 1 confer varying levels of resistance to the HIV-1 maturation inhibitor bevirimat
  2. Adamson, C. S.; Sakalian, M.; Salzwedel, K.; Freed, E. O.
  3. Retrovirology. 2010, Apr; 7: 8.
  1. 25.   Co-expression of TNFR2 and CD25 identifies more of the functional CD4(+)FOXP3(+) regulatory T cells in human peripheral blood
  2. Chen, X.; Subleski, J. J.; Hamano, R.; Howard, O. M. Z.; Wiltrout, R. H.; Oppenheim, J. J.
  3. European Journal of Immunology. 2010, Apr; 40(4): 1099-1106.
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