Skip NavigationSkip to Content

NCI at Frederick Scientific Publications Advanced Search

Search

  1. NCI-F Publications

  2. Return to Quick Search
Search
  2. Year Published:

Your search returned 70 results.
User Information
Export Records
  1. 1.   Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents
  2. Oliva, Paola; Romagnoli, Romeo; Cacciari, Barbara; Manfredini, Stefano; Padroni, Chiara; Brancale, Andrea; Ferla, Salvatore; Hamel,Ernest; Corallo, Diana; Aveic, Sanja; Milan, Noemi; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta
  3. Pharmaceutics. 2022, Jun 02; 14(6):
  1. 2.   A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents
  2. Romagnoli, Romeo; Oliva, Paola; Salvador, Maria Kimatrai; Manfredini, Stefano; Padroni, Chiara; Brancale, Andrea; Ferla, Salvatore; Hamel,Ernest; Ronca, Roberto; Maccarinelli, Federica; Rruga, Fatlum; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta
  3. European Journal of Medicinal Chemistry. 2021, Mar 15; 214
  1. 3.   Interaction of diazonamide a with tubulin
  2. Bai,Ruoli; Cruz-Monserrate, Zobeida; Fenical, William; Pettit, George R; Hamel,Ernest
  3. Archives of biochemistry and biophysics. 2020, FEB 15; 680: 108217.
  1. 4.   Synthesis and biological evaluation of structurally diverse alpha-conformationally restricted chalcones and related analogues
  2. Maguire, Casey J.; Carlson, Graham J.; Ford, Jacob W.; Strecker, Tracy E.; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G.
  3. MedChemComm. 2019, Aug 1; 10(8): 1445-1456.
  1. 5.   Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel Site
  2. Calvo, E.; Barasoain, I.; Matesanz, R.; Pera, B.; Camafeita, E.; Pineda, O.; Hamel, E.; Vanderwal, C. D.; Andreu, J. M.; Lopez, J. A.; Diaz, J. F.
  3. Biochemistry. 2012, Jan; 51(1): 329-341.
  1. 6.   Synthesis and Evaluation of 1,5-Disubstituted Tetrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative and Antitumor Activity
  2. Romagnoli, R.; Baraldi, P. G.; Salvador, M. K.; Preti, D.; Tabrizi, M. A.; Brancale, A.; Fu, X. H.; Li, J.; Zhang, S. Z.; Hamel, E.; Bortolozzi, R.; Basso, G.; Viola, G.
  3. Journal of Medicinal Chemistry. 2012, Jan; 55(1): 475-488.
  1. 7.   Design and Synthesis of 2-Heterocyclyl-3-arylthio-1H-indoles as Potent Tubulin Polymerization and Cell Growth Inhibitors with Improved Metabolic Stability
  2. La Regina, G.; Bai, R.; Rensen, W.; Coluccia, A.; Piscitelli, F.; Gatti, V.; Bolognesi, A.; Lavecchia, A.; Granata, I.; Porta, A.; Maresca, B.; Soriani, A.; Iannitto, M. L.; Mariani, M.; Santoni, A.; Brancale, A.; Ferlini, C.; Dondio, G.; Varasi, M.; Mercurio, C.; Hamel, E.; Lavia, P.; Novellino, E.; Silvestri, R.
  3. Journal of Medicinal Chemistry. 2011, Dec; 54(24): 8394-8406.
  1. 8.   Synthesis and Antitumor Molecular Mechanism of Agents Based on Amino 2-(3 ',4 ',5 '-Trimethoxybenzoyl)benzo[b]furan: Inhibition of Tubulin and Induction of Apoptosis
  2. Romagnoli, R.; Baraldi, P. G.; Lopez-Cara, C.; Cruz-Lopez, O.; Carrion, M. D.; Salvador, M. K.; Bermejo, J.; Estevez, S.; Estevez, F.; Balzarini, J.; Brancale, A.; Ricci, A.; Chen, L. C.; Kim, J. G.; Hamel, E.
  3. Chemmedchem. 2011, Oct; 6(10): 1841-1853.
  1. 9.   Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides
  2. Raffa, D.; Maggio, B.; Plescia, F.; Cascioferro, S.; Plescia, S.; Raimondi, M. V.; Daidone, G.; Tolomeo, M.; Grimaudo, S.; Di Cristina, A.; Pipitone, R. M.; Bai, R.; Hamel, E.
  3. European Journal of Medicinal Chemistry. 2011, Jul; 46(7): 2786-2796.
  1. 10.   Antitumor Agents. 284. New Desmosdumotin B Analogues with Bicyclic B-Ring as Cytotoxic and Antitubulin Agents
  2. Nakagawa-Goto, K.; Wu, P. C.; Lai, C. Y.; Hamel, E.; Zhu, H.; Zhang, L. Y.; Kozaka, T.; Ohkoshi, E.; Goto, M.; Bastow, K. F.; Lee, K. H.
  3. Journal of Medicinal Chemistry. 2011, Mar; 54(5): 1244-1255.
  1. 11.   Synthesis and Discovery of Water-Soluble Microtubule Targeting Agents that Bind to the Colchicine Site on Tubulin and Circumvent Pgp Mediated Resistance
  2. Gangjee, A.; Zhao, Y.; Lin, L.; Raghavan, S.; Roberts, E. G.; Risinger, A. L.; Hamel, E.; Mooberry, S. L.
  3. Journal of Medicinal Chemistry. 2010, Nov; 53(22): 8116-8128.
  1. 12.   Synthesis and Cellular Pharmacology Studies of a Series of 2-amino-3-aroyl-4-substituted Thiophene Derivatives
  2. Romagnoli, R.; Baraldi, P. G.; Pavani, M. G.; Cruz-Lopez, O.; Hamel, E.; Balzarini, J.; Brognara, E.; Zuccato, C.; Gambari, R.
  3. Medicinal Chemistry. 2010, Nov; 6(6): 329-343.
  1. 13.   Synthesis and Evaluation of Haloacetyl, alpha-Bromoacryloyl and Nitrooxyacetyl Benzo[b]furan and Benzo[b]thiophene Derivatives as Potent Antiproliferative Agents Against Leukemia L1210 and K562 Cells
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cara, C. L.; Casolari, A.; Hamel, E.; Fabbri, E.; Gambari, R.
  3. Letters in Drug Design & Discovery. 2010, Aug; 7(7): 476-486.
  1. 14.   Substituted 2-(3 ',4 ',5 '-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cruz-Lopez, O.; Tolomeo, M.; Grimaudo, S.; Di Cristina, A.; Pipitone, M. R.; Balzarini, J.; Brancale, A.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry. 2010, Jul; 18(14): 5114-5122.
  1. 15.   The odyssey of marine pharmaceuticals: a current pipeline perspective
  2. Mayer, A. M. S.; Glaser, K. B.; Cuevas, C.; Jacobs, R. S.; Kem, W.; Little, R. D.; McIntosh, J. M.; Newman, D. J.; Potts, B. C.; Shuster, D. E.
  3. Trends in Pharmacological Sciences. 2010, Jun; 31(6): 255-265.
  1. 16.   Peloruside B, A Potent Antitumor Macrolide from the New Zealand Marine Sponge Mycale hentscheli: Isolation, Structure, Total Synthesis, and Bioactivity
  2. Singh, A. J.; Xu, C. X.; Xu, X. M.; West, L. M.; Wilmes, A.; Chan, A.; Hamel, E.; Miller, J. H.; Northcote, P. T.; Ghosh, A. K.
  3. Journal of Organic Chemistry. 2010, Jan; 75(1): 2-10.
  1. 17.   A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent
  2. Kong, Y. L.; Wang, K.; Edler, M. C.; Hamel, E.; Mooberry, S. L.; Paige, M. A.; Brown, M. L.
  3. Bioorganic & Medicinal Chemistry. 2010, Jan; 18(2): 971-977.
  1. 18.   Intracellular Activation and Deactivation of Tasidotin, an Analog of Dolastatin 15: Correlation with Cytotoxicity
  2. Bai, R.; Edler, M. C.; Bonate, P. L.; Copeland, T. D.; Pettit, G. R.; Luduena, R. F.; Hamel, E.
  3. Molecular Pharmacology. 2009 75(1): 218-226.
  1. 19.   A diaryl sulfide, sulfoxide, and sulfone bearing structural similarities to combretastatin A-4
  2. Barbosa, E. G.; Bega, L.; Beatriz, A.; Sarkar, T.; Hamel, E.; do Amaral, M. S.; de Lima, D. P.
  3. European Journal of Medicinal Chemistry. 2009 44(6): 2685-2688.
  1. 20.   Design and Synthesis of 2-(3-Benzo[b]thienyl)-6,7-methylenedioxyquinolin-4-one Analogues as Potent Antitumor Agents that Inhibit Tubulin Assembly
  2. Chang, Y. H.; Hsu, M. H.; Wang, S. H.; Huang, L. J.; Qian, K.; Morris-Natschke, S. L.; Hamel, E.; Kuo, S. C.; Lee, K. H.
  3. Journal of Medicinal Chemistry. 2009 52(15): 4883-4891.
  1. 21.   Enantioselective Synthesis of (+)-Chamaecypanone C: A Novel Microtubule Inhibitor
  2. Dong, S. W.; Hamel, E.; Bai, R. L.; Covell, D. G.; Beutler, J. A.; Porco, J. A.
  3. Angewandte Chemie-International Edition. 2009 48(8): 1494-1497.
  1. 22.   Design, synthesis and structure-activity relationship of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of tubulin polymerization
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cara, C. L.; Cruz-Lopez, O.; Tolomeo, M.; Grimaudo, S.; Di Cristina, A.; Pipitone, M. R.; Balzarini, J.; Zonta, N.; Brancale, A.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry. 2009 17(19): 6862-6871.
  1. 23.   Hybrid alpha-bromoacryloylamido chalcones. Design, synthesis and biological evaluation
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cruz-Lopez, O.; Cara, C. L.; Balzarini, J.; Hamel, E.; Canella, A.; Fabbri, E.; Gambari, R.; Basso, G.; Viola, G.
  3. Bioorganic & Medicinal Chemistry Letters. 2009 19(7): 2022-2028.
  1. 24.   Interaction of a cyclostreptin analogue with the microtubule taxoid site: The covalent reaction rapidly follows binding
  2. Bai, R.; Vanderwal, C. D.; Diaz, J. F.; Hamel, E
  3. Journal of Natural Products. 2008 71(3): 370-374.
  1. 25.   Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198
  2. LaVallee, T. M.; Burke, P. A.; Swartz, G. M.; Hamel, E.; Agoston, G. E.; Shah, J.; Suwandi, L.; Hanson, A. D.; Fogler, W. E.; Sidor, C. F.; Treston, A. M.
  3. Molecular Cancer Therapeutics. 2008 7(6): 1472-1482.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel