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  1. 1.   Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin
  2. Madiraju, C.; Edler, M. C.; Hamel, E.; Raccor, B. S.; Balachandran, R.; Zhu, G. Y.; Giuliano, K. A.; Vogt, A.; Shin, Y. S.; Fournier, J. H.; Fukui, Y. H.; Bruckner, A. M.; Curran, D. P.; Day, B. W.
  3. Biochemistry. 2005, NOV 15; 44(45): 15053-15063.
  1. 2.   Synthesis and biological evaluation of (-)-16-normethyldictyostatin: A potent analogue of (-)-dictyostatin
  2. Shin, Y.; Fournier, J. H.; Balachandran, R.; Madiraju, C.; Raccor, B. S.; Zhu, G.; Edler, M. C.; Hamel, E.; Day, B. W.; Curran, D. P.
  3. Organic Letters. 2005, JUL 7; 7(14): 2873-2876.
  1. 3.   A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel
  2. Dabydeen, D. A.; Florence, G. J.; Paterson, I.; Hamel, E.
  3. Cancer Chemotherapy and Pharmacology. 2004 53(5): 397-403.
  1. 4.   A tale of two tumor targets: Topoisomerase I and tubulin. The Wall and Wani contribution to cancer chemotherapy
  2. Cragg, G. M.; Newman, D. J.
  3. Journal of Natural Products. 2004 67(2): 232-244.
  1. 5.   The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity
  2. Pryor, D. E.; O'Brate, A.; Bilcer, G.; Diaz, J. F.; Wang, Y. F.; Wang, Y.; Kabaki, M.; Jung, M. K.; Andreu, J. M.; Ghosh, A. K.; Giannakakou, P.; Hamel, E.
  3. Biochemistry. 2002 41(29): 9109-9115.
  1. 6.   A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells
  2. Giannakakou, P.; Gussio, R.; Nogales, E.; Downing, K. H.; Zaharevitz, D.; Bollbuck, B.; Poy, G.; Sackett, D.; Nicolaou, K. C.; Fojo, T.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2000 97(6): 2904-2909.
  1. 7.   The coral-derived natural products eleutherobin and sarcodictyins A and B: Effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site
  2. Hamel, E.; Sackett, D. L.; Vourloumis, D.; Nicolaou, K. C.
  3. Biochemistry. 1999 38(17): 5490-5498.
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