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  1. 1.   Exploration of Ultralarge Compound Collections for Drug Discovery
  2. Warr, Wendy A; Nicklaus,Marc; Nicolaou, Christos A; Rarey, Matthias
  3. Journal of Chemical Information and Modeling. 2022, Apr 14;
  1. 2.   CRISPR-targeted MAGT1 insertion restores XMEN patient hematopoietic stem cells and lymphocytes
  2. Brault, Julie; Liu, Taylor; Bello, Ezekiel; Liu, Siyuan; Sweeney, Colin L.; Meis, Ronald J.; Koontz, Sherry; Corsino, Cristina; Choi, Uimook; Vayssiere, Guillaume; Bosticardo, Marita; Dowdell, Kennichi; Lazzarotto, Cicera R.; Clark, Aaron B.; Notarangelo, Luigi D.; Ravell, Juan C.; Lenardo, Michael J.; Kleinstiver, Benjamin P.; Tsai, Shengdar Q.; Wu, Xiaolin; Dahl, Gary A.; Malech, Harry L.; De Ravin, Suk See
  3. Blood. 2021, Dec 30; 138(26): 2768-2780.
  1. 3.   The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress
  2. Stromberg, Benjamin R.; Singh, Mayank; Torres, Adrian E.; Burrows, Amy C.; Pal, Debjani; Insinna, Christine; Rhee, Yosup; Dickson, Andrew S.; Westlake,Christopher; Summers, Matthew K.
  3. The Journal of Biological Chemistry. 2021, Oct; 297(4):
  1. 4.   The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation
  2. Xu,Xiaoping; Ni, Kai; He,Yafeng; Ren, Jianke; Sun, Chongkui; Liu, Yie; Aladjem, Mirit; Burkett, Sandra; Finney, Richard; Ding, Xia; Sharan,Shyam; Muegge,Kathrin
  3. Nature communications. 2021, Jun 10; 12(1):
  1. 5.   Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors
  2. Takebe, Naoko; Naqash, Abdul Rafeh; Coyne, Geraldine O'Sullivan; Kummar, Shivaani; Do, Khanh; Bruns, Ashley; Juwara,Lamin; Zlott, Jennifer; Rubinstein, Larry; Piekarz, Richard; Sharon, Elad; Streicher, Howard; Mittra, Arjun; Miller, Sarah B.; Ji,Jay; Wilsker,Deborah; Kinders,Robert; Parchment,Ralph; Chen,Li; Chang,Ting-Chia; Das,Biswajit; Mugundu, Ganesh; Doroshow, James H.; Chen, Alice P.
  3. CLINICAL CANCER RESEARCH. 2021, Apr 16; 27(14): 3834-3844.
  1. 6.   A brain-penetrant microtubule-targeting agent that disrupts hallmarks of glioma tumorigenesis
  2. Horne, Eric A; Diaz, Philippe; Cimino, Patrick J; Jung, Erik; Xu, Cong; Hamel,Ernest; Wagenbach, Michael; Kumasaka, Debra; Wageling, Nicholas B; Azorín, Daniel D; Winkler, Frank; Wordeman, Linda G; Holland, Eric C; Stella, Nephi
  3. Neuro-oncology advances. 2021, Jan-Dec; 3(1): vdaa165.
  1. 7.   A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays
  2. Biswas,Kajal; Lipton, Gary B; Stauffer,Stacey; Sullivan,Teresa; Cleveland, Linda; Southon,Eileen; Reid,Susan; Magidson,Valentin; Iversen, Edwin S; Sharan,Shyam
  3. NPJ genomic medicine. 2020, Dec 08; 5(1): 52.
  1. 8.   Noncoding Y RNAs regulate the levels, subcellular distribution and protein interactions of their Ro60 autoantigen partner
  2. Leng,Yuanyuan; Sim,Soyeong; Magidson,Valentin; Wolin,Sandra
  3. Nucleic acids research. 2020, JUL 9; 48(12): 6919-6930.
  1. 9.   Blood RNA Integrity is a Direct and Simple Reporter of Radiation Exposure and Prognosis: A Pilot Study
  2. Alkhalil, Abdulnaser; Clifford, John L; Ball, Robert; Day, Anna; Chan, Rossana; Carney, Bonnie C; Miller, Stacy Ann; Campbell, Ross; Kumar, Raina; Gautam, Aarti; Hammamieh, Rasha; Moffatt, Lauren T; Shupp, Jeffrey W
  3. Radiation research. 2020, JUN; 193(6): 543-551.
  1. 10.   Tumour predisposition and cancer syndromes as models to study gene-environment interactions
  2. Carbone, Michele; Arron, Sarah T.; Beutler, Bruce; Bononi, Angela; Cavenee, Webster; Cleaver, James E.; Croce, Carlo M.; D'Andrea, Alan; Foulke, William D.; Gaudino, Giovanni; Groden, Joanna L.; Henske, Elizabeth P.; Hickson, Ian D.; Hwang, Paul M.; Kolodner, Richard D.; Mak, Tak W.; Malkin, David; Monnat, Raymond J. Jr Jr; Novelli, Flavia; Pass, Harvey; Petrini, John H.; Schmidt,Laura; Yang, Haining
  3. Nature reviews. Cancer. 2020, May 29;
  1. 11.   Regulation of senescence and the SASP by the transcription factor C/EBP beta
  2. Salotti,Jacqueline; Johnson,Peter
  3. Experimental gerontology. 2019, Dec; 128
  1. 12.   Elements in the ? Immunity Region Regulate Phage Development: Beyond the "Genetic Switch"
  2. Thomason,Lynn; Morrill, Kathleen; Murray, Gillian; Court,Carolyn; Shafer, Brenda; Schneider,Tom; Court,Don
  3. Molecular microbiology. 2019, DEC; 112(6): 1798-1813.
  1. 13.   Phase I and Pharmacology Study of Ropidoxuridine (IPdR) as Prodrug for Iododeoxyuridine-Mediated Tumor Radiosensitization in Advanced GI Cancer Undergoing Radiation
  2. Kinsella, Timothy; Safran, Howard; Wiersma, Susan; DiPetrillo, Thomas; Schumacher, Andrew; Rosati, Kayla; Vatkevich, John; Anderson, Lawrence W.; Hill,Kimberly; Kunos, Charles; Collins,Jerry
  3. CLINICAL CANCER RESEARCH. 2019, Oct 15; 25(20): 6035-6043.
  1. 14.   Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae
  2. Jiao,Xiaoli; Sui,Hongyan; Lyons, Christopher; Tran,Bao; Sherman,Brad; Imamichi,Tomozumi
  3. Microbiology resource announcements. 2019, Sep 26; 8(39): pii: e00993-19. .
  1. 15.   Complete Genome Sequence of Herpes Simplex Virus 1 Strain MacIntyre
  2. Jiao,Xiaoli; Sui,Hongyan; Lyons, Christopher; Tran,Bao; Sherman,Brad; Imamichi,Tomozumi
  3. Microbiology resource announcements. 2019, Sep 12; 8(37): pii: e00895-19.
  1. 16.   Viral, immunologic, and clinical features of primary effusion lymphoma
  2. Lurain, Kathryn; Polizzotto, Mark N.; Aleman, Karen; Bhutani, Manisha; Wyvill, Kathleen M.; Goncalves, Priscila H.; Ramaswami, Ramya; Marshall,Vickie; Miley,Wendell; Steinberg, Seth M.; Little, Richard F.; Wilson, Wyndham; Filie, Armando C.; Pittaluga, Stefania; Jaffe, Elaine S.; Whitby,Denise; Yarchoan, Robert; Uldrick, Thomas S.
  3. Blood. 2019, Apr 18; 133(16): 1753-1761.
  1. 17.   BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation
  2. Zong, Dali; Adam, Salome; Wang, Yifan; Sasanuma, Hiroyuki; Callen, Elsa; Murga, Matilde; Day, Amanda; Kruhlak, Michael J.; Wong, Nancy; Munro, Meagan; Chaudhuri, Arnab Ray; Karim,Baktiar; Xia, Bing; Takeda, Shunichi; Johnson, Neil; Durocher, Daniel; Nussenzweig, Andre
  3. Molecular cell. 2019, MAR 21; 73(6): 1267-+.
  1. 18.   Structures and operating principles of the replisome
  2. Gao, Yang; Cui, Yanxiang; Fox,Tara; Lin, Shiqiang; Wang, Huaibin; De Val Alda,Natalia; Zhou, Z. Hong; Yang, Wei
  3. Science (New York, N.Y.). 2019, Feb 22; 363: 835-+.
  1. 19.   IFNL4-Delta G Allele Is Associated with an Interferon Signature in Tumors and Survival of African-American Men with Prostate Cancer
  2. Tang, Wei; Wallace, Tiffany A.; Yi, Ming; Magi-Galluzzi, Cristina; Dorsey, Tiffany H.; Onabajo, Olusegun O.; Obajemu, Adeola; Jordan, Symone V.; Loffredo, Christopher A.; Stephens, Bob; Silverman, Robert H.; Stark, George R.; Klein, Eric A.; Prokunina-Olsson, Ludmila; Ambs, Stefan
  3. CLINICAL CANCER RESEARCH. 2018, Nov 1; 24(21): 5471-5481.
  1. 20.   Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer
  2. Singh, Krishna B.; Ji,Xinhua; Singh, Shivendra V.
  3. MOLECULAR CANCER THERAPEUTICS. 2018, Oct; 17(10): 2079-2090.
  1. 21.   Inhibition of Bacterial Gene Transcription with an RpoN-Based Stapled Peptide
  2. Payne, Sterling R; Pau, Daniel I; Whiting, Amanda L; Kim, Ye Joon; Pharoah, Blaze M; Moi, Christina; Boddy, Christopher N; Bernal, Federico
  3. Cell Chemical Biology. 2018, Sep 20; 25(9): 1059-1066.e4.
  1. 22.   A G3BP1-Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53
  2. Mao, Chao; Wang, Xiang; Liu, Yating; Wang, Min; Jiang, Yiqun; Shi, Ying; Shen, Yi; Liu, Xiaoli; Lai, Weiwei; Yang, Rui; Xiao, Desheng; Cheng, Yan; Liu, Shuang; Zhou, Hu; Cao, Ya; Yu, Weishi; Muegge, Kathrin; Yu, Herbert; Tao, Yongguang
  3. CANCER RESEARCH. 2018, Jul 1; 78(13): 3484-3496.
  1. 23.   LMTK3 confers chemo-resistance in breast cancer
  2. Stebbing, Justin; Shah, Kalpit; Lit, Lei Cheng; Gagliano, Teresa; Ditsiou, Angeliki; Wang, Tingting; Wendler, Franz; Simon, Thomas; Szabo, Krisztina Sara; O'Hanlon, Tim; Dean, Michael; Roslani, April Camilla; Cheah, Swee Hung; Lee, Soo-Chin; Giamas, Georgios
  3. ONCOGENE. 2018, JUN; 37(23): 3113-3130.
  1. 24.   Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex
  2. Guo, Tai Wei; Bartesaghi, Alberto; Yang, Hui; Falconieri, Veronica; Rao, Prashant; Merk, Alan; Eng, Edward T; Raczkowski, Ashleigh M; Fox, Tara; Earl, Lesley A; Patel, Dinshaw J; Subramaniam, Sriram
  3. Cell. 2017, Oct 05; 171(2): 414-426.e12.
  1. 25.   Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies
  2. Nayar, Utthara; Sadek, Jouliana; Reichel, Jonathan; Hernandez-Hopkins, Denise; Akar, Gunkut; Barelli, Peter J.; Sahai, Michelle A.; Zhou, Hufeng; Totonchy, Jennifer; Jayabalan, David; Niesvizky, Ruben; Guasparri, Ilaria; Hassane, Duane; Liu, Yifang; Sei, Shizuko; Shoemaker, Robert; Warren, J. David; Elemento, Olivier; Kaye, Kenneth M.; Cesarman, Ethel
  3. JOURNAL OF CLINICAL INVESTIGATION. 2017, Jun; 127(6): 2066-2080.
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