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  1. 1.   An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics
  2. Borhani, Shayan G; Levine, Max Z; Krumpe,Lauren; Wilson,Jennifer; Henrich,Curtis; O'Keefe,Barry; Lo, Donald C; Sittampalam, G Sitta; Godfrey, Alexander G; Lunsford, R Dwayne; Mangalampalli, Venkata; Tao, Dingyin; LeClair, Christopher A; Thole, Aaron P; Frey, Douglas; Swartz, James; Rao, Govind
  3. New Biotechnology. 2023, Apr 11; 76: 13-22.
  1. 2.   Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture
  2. Shrivastava-Ranjan, Punya; Lo, Michael K.; Chatterjee, Payel; Flint, Mike; Nichol, Stuart T.; Montgomery, Joel M.; O'Keefe,Barry; Spiropoulou, Christina F.
  3. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2020, NOV 4; 10: 561502.
  1. 3.   Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge
  2. Lo, Michael K; Spengler, Jessica R; Haugh Krumpe,Lauren; Welch, Stephen R; Chattopadhyay, Anasuya; Harmon, Jessica R; Coleman-McCray, Joann D; Scholte, Florine E M; Hotard, Anne L; Fuqua, Joshua L; Rose, John K; Nichol, Stuart T; Palmer, Kenneth E; O'Keefe,Barry; Spiropoulou, Christina F
  3. The Journal of infectious diseases. 2020, MAY 1; 221(Supp. 4): S480-S492.
  1. 4.   The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells
  2. Alexandre, K. B.; Gray, E. S.; Mufhandu, H.; McMahon, J. B.; Chakauya, E.; O'Keefe, B. R.; Chikwamba, R.; Morris, L.
  3. Virology. 2012, Feb; 423(2): 175-186.
  1. 5.   Binding of the Mannose-Specific Lectin, Griffithsin, to HIV-1 gp120 Exposes the CD4-Binding Site
  2. Alexandre, K. B.; Gray, E. S.; Pantophlet, R.; Moore, P. L.; McMahon, J. B.; Chakauya, E.; O'Keefe, B. R.; Chikwamba, R.; Morris, L.
  3. Journal of Virology. 2011, Sep; 85(17): 9039-9050.
  1. 6.   Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate
  2. Kouokam, J. C.; Huskens, D.; Schols, D.; Johannemann, A.; Riedell, S. K.; Walter, W.; Walker, J. M.; Matoba, N.; O'Keefe, B. R.; Palmer, K. E.
  3. Plos One. 2011, Aug; 6(8):
  1. 7.   Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity
  2. Moulaei, T.; Shenoy, S. R.; Giomarelli, B.; Thomas, C.; McMahon, J. B.; Dauter, Z.; O'Keefe, B. R.; Wlodawer, A.
  3. Structure. 2010, Sep; 18(9): 1104-1115.
  1. 8.   Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin
  2. Alexandre, K. B.; Gray, E. S.; Lambson, B. E.; Moore, P. L.; Choge, I. A.; Mlisana, K.; Karim, S. S. A.; McMahon, J.; O'Keefe, B.; Chikwamba, R.; Morris, L.
  3. Virology. 2010, Jun; 402(1): 187-196.
  1. 9.   Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component
  2. O'Keefe, B. R.; Vojdani, F.; Buffa, V.; Shattock, R. J.; Montefiori, D. C.; Bakke, J.; Mirsalis, J.; d'Andrea, A. L.; Hume, S. D.; Bratcher, B.; Saucedo, C. J.; McMahon, J. B.; Pogue, G. P.; Palmer, K. E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(15): 6099-6104.
  1. 10.   Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide
  2. Emau, P.; Tian, B.; O'Keefa, B. R.; Mori, T.; McMahon, J. B.; Palmer, K. E.; Jiang, Y.; Bekele, G.; Tsai, C. C.
  3. Journal of Medical Primatology. 2007, Aug; 36(4-5): 244-253.
  1. 11.   Recombinant production of anti-HIV protein, griffithsin, by auto-induction in a fermentor culture
  2. Giomarelli, B.; Schumacher, K. M.; Taylor, T. E.; Sowder, R. C.; Hartley, J. L.; McMahon, J. B.; Mori, T.
  3. Protein Expression and Purification. 2006, MAY; 47(1): 194-202.
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