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  1. 1.   CT-707 overcomes hypoxia-mediated sorafenib resistance in Hepatocellular carcinoma by inhibiting YAP signaling
  2. Chen,Zibo; Yuan, Tao; Yan, Fangjie; Ye, Song; Xie, Qin; Zhang, Bo; Lin, Nengmin; He, Qiaojun; Yang, Bo; Zhu, Hong
  3. BMC Cancer. 2022, Apr 19; 22(1): 425.
  1. 2.   Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability
  2. Kharat,Suhas; Ding, Xia; Swaminathan, Divya; Suresh, Akshey; Singh, Manish; Sengodan,Satheesh; Burkett,Sandra; Marks, Hanna; Pamala, Chinmayi; He,Yafeng; Fox,Stephen; Buehler, Eugen C; Muegge,Kathrin; Martin, Scott E; Sharan,Shyam
  3. Science signaling. 2020, Aug 18; 13(645): pii: eaba8091.
  1. 3.   Vav1 is Essential for HIF-1a Activation via a Lysosomal VEGFR1-Mediated Degradation Mechanism in Endothelial Cells
  2. Hong,Jaewoo; Min,Yongfen; Wuest, Todd; Lin,Charles
  3. Cancers. 2020, JUN; 12(6): E1374.
  1. 4.   The Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates Hif-1 alpha and Glut-1 Expression and Glucose Uptake in the Brain
  2. Hong,Jaewoo; Kim, Yurim; Yanpallewar,Sudhirkumar; Lin,Charles
  3. International journal of molecular sciences. 2020, FEB; 21(4):
  1. 5.   Oxygen Tension Regulates Lysosomal Activation and Receptor Tyrosine Kinase Degradation
  2. Hong,Jaewoo; Wuest, Todd R; Min,Yongfen; Lin,Charles
  3. Cancers. 2019, Nov; 11(11): pii: E1653..
  1. 6.   Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models
  2. Harris, Emily M; Strope, Jonathan D; Beedie, Shaunna L; Huang, Phoebe A; Goey, Andrew K L; Cook, Kristina M; Schofield, Christopher J; Chau, Cindy H; Cadelis, Melissa M; Copp, Brent R; Gustafson, Kirk; Figg, William D
  3. Marine Drugs. 2018, Jul 19; 16(7): pii: E241.
  1. 7.   Restricted exchange microenvironments for cell culture
  2. Hoh, Jan H; Werbin, Jeffrey L; Heinz, Will
  3. BioTechniques. 2018, Mar 01; 64(3): 101-109.
  1. 8.   Bioreductively activatable prodrug conjugates of phenstatin designed to target tumor hypoxia
  2. Winn, Blake A; Shi, Zhe; Carlson, Graham J; Wang, Yifan; Nguyen, Benson L; Kelly, Evan M; Ross, R David; Hamel, Ernest; Chaplin, David J; Trawick, Mary L; Pinney, Kevin G
  3. Bioorganic & medicinal chemistry letters. 2017, Feb 01; 27(3): 636-641.
  1. 9.   Near-infrared uncaging or photosensitizing dictated by oxygen tension
  2. Anderson, E. D.; Gorka, A. P.; Schnermann, M. J.
  3. Nature Communications. 2016, 17-Nov; 7: 13378.
  1. 10.   Hypoxia, stem cells and bone tumor
  2. Zeng, W.; Wan, R.; Zheng, Y. H.; Singh, S. R.; Wei, Y. Y.
  3. Cancer Letters. 2011, Dec; 313(2): 129-136.
  1. 11.   Inactivation of the von Hippel-Lindau tumor suppressor leads to selective expression of a human endogenous retrovirus in kidney cancer
  2. Cherkasova, E.; Malinzak, E.; Rao, S.; Takahashi, Y.; Senchenko, V. N.; Kudryavtseva, A. V.; Nickerson, M. L.; Merino, M.; Hong, J. A.; Schrump, D. S.; Srinivasan, R.; Linehan, W. M.; Tian, X.; Lerman, M. I.; Childs, R. W.
  3. Oncogene. 2011, Nov; 30(47): 4697-4706.
  1. 12.   Epigenetic Regulation of Endothelial Lineage Committed Genes in Pro-Angiogenic Hematopoietic and Endothelial Progenitor Cells
  2. Ohtani, K.; Vlachojannis, G. J.; Koyanagi, M.; Boeckel, J. N.; Urbich, C.; Farcas, R.; Bonig, H.; Marquez, V. E.; Zeiher, A. M.; Dimmeler, S.
  3. Circulation Research. 2011, Nov; 109(11): 1219-U71.
  1. 13.   The cancer stem cell niche-there goes the neighborhood?
  2. Cabarcas, S. M.; Mathews, L. A.; Farrar, W. L.
  3. International Journal of Cancer. 2011, Nov; 129(10): 2315-2327.
  1. 14.   The HIF-1 alpha-c-Myc pathway and tumorigenesis: Evading the apoptotic gatekeeper
  2. Fer, N.; Melillo, G.
  3. Cell Cycle. 2011, Oct; 10(19): 3228-3228.
  1. 15.   RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
  2. Lipkowitz, S.; Weissman, A. M.
  3. Nature Reviews Cancer. 2011, Sep; 11(9): 629-643.
  1. 16.   A New Hypoxia Inducible Factor-2 Inhibitory Pyrrolinone Alkaloid from Roots and Stems of Piper sarmentosum
  2. Bokesch, H. R.; Gardella, R. S.; Rabe, D. C.; Bottaro, D. P.; Linehan, W. M.; McMahon, J. B.; McKee, T. C.
  3. Chemical & Pharmaceutical Bulletin. 2011, Sep; 59(9): 1178-1179.
  1. 17.   The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling
  2. Ping, Y. F.; Yao, X. H.; Jiang, J. Y.; Zhao, L. T.; Yu, S. C.; Jiang, T.; Lin, M. C. M.; Chen, J. H.; Wang, B.; Zhang, R.; Cui, Y. H.; Qian, C.; Wang, J. M.; Bian, X. W.
  3. Journal of Pathology. 2011, Jul; 224(3): 344-354.
  1. 18.   ASPS-1, A Novel Cell Line Manifesting Key Features of Alveolar Soft Part Sarcoma
  2. Kenney, S.; Vistica, D. T.; Stockwin, L. H.; Burkett, S.; Hollingshead, M. G.; Borgel, S. D.; Butcher, D. O.; Schrump, D. S.; Shoemaker, R. H.
  3. Journal of Pediatric Hematology Oncology. 2011, Jul; 33(5): 360-368.
  1. 19.   A versatile valve-enabled microfluidic cell co-culture platform and demonstration of its applications to neurobiology and cancer biology
  2. Gao, Y. D.; Majumdar, D.; Jovanovic, B.; Shaifer, C.; Lin, P. C.; Zijlstra, A.; Webb, D. J.; Li, D. Y.
  3. Biomedical Microdevices. 2011, Jun; 13(3): 539-548.
  1. 20.   Large-scale Exploration of Gene-Gene Interactions in Prostate Cancer Using a Multistage Genome-wide Association Study
  2. Ciampa, J.; Yeager, M.; Amundadottir, L.; Jacobs, K.; Kraft, P.; Chung, C.; Wacholder, S.; Yu, K.; Wheeler, W.; Thun, M. J.; Divers, W. R.; Gapstur, S.; Albanes, D.; Virtamo, J.; Weinstein, S.; Giovannucci, E.; Willett, W. C.; Cancel-Tassin, G.; Cussenot, O.; Valeri, A.; Hunter, D.; Hoover, R.; Thomas, G.; Chanock, S.; Chatterjee, N.
  3. Cancer Research. 2011, May; 71(9): 3287-3295.
  1. 21.   Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC
  2. Stockwin, L. H.; Yu, S. X.; Borgel, S.; Hancock, C.; Wolfe, T. L.; Phillips, L. R.; Hollingshead, M. G.; Newton, D. L.
  3. International Journal of Cancer. 2010, Dec; 127(11): 2510-2519.
  1. 22.   The tumour suppressor C/EBP delta inhibits FBXW7 expression and promotes mammary tumour metastasis
  2. Balamurugan, K.; Wang, J. M.; Tsai, H. H.; Sharan, S.; Anver, M.; Leighty, R.; Sterneck, E.
  3. Embo Journal. 2010, Dec; 29(24): 4106-4117.
  1. 23.   Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1 alpha Expression in an AhR-Independent Fashion
  2. Terzuoli, E.; Puppo, M.; Rapisarda, A.; Uranchimeg, B.; Cao, L. A.; Burger, A. M.; Ziche, M.; Melillo, G.
  3. Cancer Research. 2010, Sep 1; 70(17): 6837-6848.
  1. 24.   Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion
  2. Santhanam, A. N.; Baker, A. R.; Hegamyer, G.; Kirschmann, D. A.; Colburn, N. H.
  3. Oncogene. 2010, Jul; 29(27): 3921-3932.
  1. 25.   T cells, not "immune" from HIF
  2. Melillo, G.
  3. Journal of Leukocyte Biology. 2010, Mar; 87(3): 359-361.
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