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  1. 1.   Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors
  2. Ng,Martin; Wang, Huanchen; Zhang, Haibo; Prucker, Isabel; Perera, Lalith; Goncharova,Katya; Wamiru,Antony; Jessen, Henning J; Stanley, Robin E; Shears, Stephen B; Luo, Ji; O'Keefe,Barry; Wilson,Brice
  3. The Journal of Biological Chemistry. 2025, Feb 06; 108274.
  1. 2.   Essential functions of inositol hexakisphosphate (IP6) in murine leukemia virus replication
  2. Biswas, Banhi; Lai,Kin Kui; Bracey, Harrison; Datta,Siddhartha; Harvin, Demetria; Sowd, Gregory A; Aiken, Christopher; Rein,Alan
  3. mBio. 2024, Jul 17; 15(7): e0115824.
  1. 3.   The Effect of Inositol Hexakisphosphate on HIV-1 Particle Production and Infectivity can be Modulated by Mutations that Affect the Stability of the Immature Gag Lattice
  2. Kleinpeter,Alex; Zhu, Yanan; Mallery, Donna L; Ablan,Sherimay; Chen, Long; Hardenbrook, Nathan; Saiardi, Adolfo; James, Leo C; Zhang, Peijun; Freed,Eric
  3. Journal of Molecular Biology. 2023, Apr 01; 435(11): 168037.
  1. 4.   Cellular IP6 Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP6 Are Attenuated for Infection and Replication
  2. Mallery, Donna L; Faysal, K M Rifat; Kleinpeter,Alex; Wilson, Miranda S C; Vaysburd, Marina; Fletcher, Adam J; Novikova, Mariia; Böcking, Till; Freed,Eric; Saiardi, Adolfo; James, Leo C
  3. Cell reports. 2019, Dec 17; 29(12): 3983-3996.e4.
  1. 5.   Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate
  2. Roy, Neeladri Sekhar; Jian, Xiaoying; Soubias,Olivier; Zhai, Peng; Hall, Jessica R.; Dagher, Jessica N.; Coussens, Nathan P.; Jenkins, Lisa M.; Luo, Ruibai; Akpan, Itoro O.; Hall, Matthew D.; Byrd,Robert; Yohe, Marielle E.; Randazzo, Paul A.
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2019, NOV 15; 294(46): 17354-17370.
  1. 6.   The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin
  2. Jang,Hyunbum; Banerjee, Avik; Marcus, Kendra; Makowski, Lee; Mattos, Carla; Gaponenko, Vadim; Nussinov,Ruth
  3. Structure (London, England : 1993). 2019, Nov 5; 27(11): 1647-1659.e4.
  1. 7.   Calmodulin (CaM) Activates PI3K alpha by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85 alpha
  2. Zhang,Mingzhen; Li, Zhigang; Wang, Guanqiao; Jang,Hyunbum; Sacks, David B.; Zhang, Jian; Gaponenko, Vadim; Nussinov,Ruth
  3. JOURNAL OF PHYSICAL CHEMISTRY B. 2018, Dec 13; 122(49): 11137-11146.
  1. 8.   Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit
  2. Wang, Guanqiao; Zhang, Mingzhen; Jang, Hyunbum; Lu, Shaoyong; Lin, Shizhou; Chen, Guoqiang; Nussinov, Ruth; Zhang, Jian; Gaponenko, Vadim
  3. Biochemistry. 2018, Mar 27; 57(12): 1917-1928.
  1. 9.   Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy
  2. Logue, J. S.; Morrison, D. K.
  3. Genes & Development. 2012, Apr; 26(7): 641-650.
  1. 11.   Anti-HIV-1 antibodies 2F5 and 4E10 interact differently with lipids to bind their epitopes
  2. Franquelim, H. G.; Chiantia, S.; Veiga, A. S.; Santos, N. C.; Schwille, P.; Castanho, M.
  3. Aids. 2011, Feb; 25(4): 419-428.
  1. 12.   Electrostatic Interactions and Binding Orientation of HIV-1 Matrix Studied by Neutron Reflectivity
  2. Nanda, H.; Datta, S. A. K.; Heinrich, F.; Losche, M.; Rein, A.; Krueger, S.; Curtis, J. E.
  3. Biophysical Journal. 2010, Oct; 99(8): 2516-2524.
  1. 14.   Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1
  2. Fer, N. D.; Shoemaker, R. H.; Monks, A.
  3. Journal of Experimental & Clinical Cancer Research. 2010, Jul; 29: 7.
  1. 15.   Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1
  2. Gruber, S. G.; Luciani, M. G.; Grundtner, P.; Zdanov, A.; Gasche, C.
  3. European Journal of Immunology. 2008 38(12): 3365-3375.
  1. 16.   Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens
  2. Zhang, M. Y.; Vu, B. K.; Choudhary, A.; Lu, H.; Humbert, M.; Ong, H.; Alam, M.; Ruprecht, R. M.; Quinnan, G.; Jiang, S.; Montefiori, D. C.; Mascola, J. R.; Broder, C. C.; Haynes, B. F.; Dimitrov, D. S.
  3. Journal of Virology. 2008 82(14): 6869-6879.
  1. 17.   Differential gene expression in skeletal muscle cells after membrane depolarization
  2. Juretic, N.; Urzua, U.; Munroe, D. J.; Jaimovich, E.; Riveros, N.
  3. Journal of Cellular Physiology. 2007, Mar; 210(3): 819-830.
  1. 18.   Point mutations in the HIV-1 matrix protein turn off the myristyl switch
  2. Saad, J. S.; Loeliger, E.; Luncsford, P.; Liriano, M.; Tai, J.; Kim, A.; Miller, J.; Joshi, A.; Freed, E. O.; Summers, M. F.
  3. Journal of Molecular Biology. 2007, Feb; 366(2): 574-585.
  1. 19.   CK2 is a component of the KSR1 scaffold complex that contributes to Raf kinase activation
  2. Ritt, D. A.; Zhou, M.; Conrads, T. P.; Veenstra, T. D.; Copeland, T. D.; Morrison, D. K.
  3. Current Biology. 2007, Jan; 17(2): 179-184.
  1. 20.   Role of the intracellular domain of IL-7 receptor in T cell development
  2. Jiang, Q.; Huang, J.; Li, W. Q.; Cavinato, T.; Keller, J. R.; Durum, S. K.
  3. Journal of Immunology. 2007, Jan; 178(1): 228-234.
  1. 21.   Interactions between HIV-1 Gag molecules in solution: An inositol phosphate-mediated switch
  2. Datta, S. A. K.; Zhao, Z.; Clark, P. K.; Tarasov, S.; Alexandratos, J. N.; Campbell, S. J.; Kvaratskhelia, M.; Lebowitz, J.; Rein, A.
  3. Journal of Molecular Biology. 2007, Jan; 365(3): 799-811.
  1. 22.   Gab1 is required for cell cycle transition, cell proliferation, and transformation induced by an oncogenic Met receptor
  2. Mood, K.; Saucier, C.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Molecular Biology of the Cell. 2006, Sep; 17(9): 3717-3728.
  1. 23.   Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma
  2. Rudelius, M.; Pittaluga, S.; Nishizuka, S.; Pham, T. H. T.; Fend, F.; Jaffe, E. S.; Quintanilla-Martinez, L.; Raffeld, M.
  3. Blood. 2006, Sep; 108(5): 1668-1676.
  1. 24.   Oncogenic met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling
  2. Mood, K.; Saucier, C.; Ishimura, A.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Journal of Cellular Physiology. 2006, APR; 207(1): 271-285.
  1. 25.   Ligand-induced partitioning of human CXCR1 chemokine receptors with lipid raft microenvironments facilitates G-protein-dependent signaling
  2. Jiao, X. M.; Zhang, N.; Xu, X. H.; Oppenheim, J. J.; Jin, T.
  3. Molecular and Cellular Biology. 2005, JUL; 25(13): 5752-5762.
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