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  1. 1.   Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease
  2. Mao, Liming; Kitani, Atsushi; Similuk, Morgan; Oler, Andrew J.; Albenberg, Lindsey; Kelsen, Judith; Aktay, Atiye; Quezado, Martha; Yao, Michael; Montgomery-Recht, Kim; Fuss, Ivan J.; Strober, Warren
  3. Journal of Clinical Investigation. 2018, May 01; 128(5): 1793-1806.
  1. 2.   IKK alpha controls ATG16L1 degradation to prevent ER stress during inflammation
  2. Diamanti, Michaela A.; Gupta, Jalaj; Bennecke, Moritz; De Oliveira, Tiago; Ramakrishnan, Mallika; Braczynski, Anne K.; Richter, Benjamin; Beli, Petra; Hu, Yinling; Saleh, Maya; Mittelbronn, Michel; Dikic, Ivan; Greten, Florian R.
  3. JOURNAL OF EXPERIMENTAL MEDICINE. 2017, 2017-02-01; 214(2): 423-437.
  1. 3.   MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
  2. Salcedo, R.; Worschech, A.; Cardone, M.; Jones, Y.; Gyulai, Z.; Dai, R. M.; Wang, E. N.; Ma, W.; Haines, D.; O'HUigin, C.; Marincola, F. M.; Trinchieri, G.
  3. Journal of Experimental Medicine. 2010, Aug 2; 207(8): 1625-1636.
  1. 4.   Synergy of IL-23 and Th17 Cytokines: New Light on Inflammatory Bowel Disease
  2. Shen, W.; Durum, S. K.
  3. Neurochemical Research. 2010, Jun; 35(6): 940-946.
  1. 5.   Development of regulatory T cells requires IL-7R alpha stimulation by IL-7 or TSLP
  2. Mazzucchelli, R.; Hixon, J. A.; Spolski, R.; Chen, X.; Li, W. Q.; Hall, V. L.; Willette-Brown, J.; Hurwitz, A. A.; Leonard, W. J.; Durum, S. K.
  3. Blood. 2008, Oct 15; 112(8): 3283-3292.
  1. 6.   Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody
  2. Fuss, I. J.; Becker, C.; Yang, Z. Q.; Groden, C.; Hornung, R. L.; Heller, F.; Neurath, M. F.; Strober, W.; Mannon, P. J.
  3. Inflammatory Bowel Diseases. 2006, JAN; 12(1): 9-15.
  1. 7.   Induction of colitis by a CD4(+) T cell clone specific for a bacterial epitope
  2. Kullberg, M. C.; Andersen, J. F.; Gorelick, P. L.; Caspar, P.; Suerbaum, S.; Fox, J. G.; Cheever, A. W.; Jankovic, D.; Sher, A.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2003 100(26): 15830-15835.
  1. 8.   Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis
  2. Kullberg, M. C.; Jankovic, D.; Gorelick, P. L.; Caspar, P.; Letterio, J. J.; Cheever, A. W.; Sher, A.
  3. Journal of Experimental Medicine. 2002 196(4): 505-515.
  1. 9.   Helicobacter Hepaticus Triggers Colitis in Specific-Pathogen-Free Interleukin-10 (Il-10)-Deficient Mice Through an Il-12- and Gamma Interferon-Dependent Mechanism
  2. Kullberg, M. C.; Ward, J. M.; Gorelick, P. L.; Caspar, P.; Hieny, S.; Cheever, A.; Jankovic, D.; Sher, A.
  3. Infection and Immunity. 1998 66(11): 5157-5166.
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