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  1. 1.   Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma
  2. Stauffer,Stacey; Roth, Jacob S; Hernandez, Edjay R; Kowalczyk, Joshua T; Sealover, Nancy E; Hebron,Katie; James,Amy; Isanogle,Kristine; Riffle, Lisa A; Ileva,Lilia; Luo, Xiaoling; Chen, Jin-Qiu; Kedei, Noemi; Kortum, Robert L; Lei, Haiyan; Shern, Jack F; Kalen,Joseph; Edmondson, Elijah F; Hall, Matthew D; Difilippantonio,Simone; Thiele, Carol J; Yohe,Marielle
  3. Cancers. 2024, Jun 25; 16(13):
  1. 2.   Long-Term Safety and Efficacy of Selumetinib in Children with Neurofibromatosis Type 1 on a Phase 1/2 Trial for Inoperable Plexiform Neurofibromas
  2. Gross, Andrea M; Dombi, Eva; Wolters, Pamela L; Baldwin, Andrea; Dufek, Anne; Herrera, Kailey; Martin, Staci; Derdak, Joanne; Heisey,Kara; Whitcomb, Patricia M; Steinberg, Seth M; Venzon, David J; Fisher, Michael J; Kim, Ae Rang; Bornhorst, Miriam; Weiss, Brian D; Blakeley, Jaishri O; Smith, Malcolm A; Widemann, Brigitte C
  3. Neuro-Oncology. 2023, Apr 28;
  1. 3.   Inhibition of HSP 90 is associated with potent anti-tumor activity in Papillary Renal Cell Carcinoma
  2. Pahwa, Roma; Dubhashi, Janhavi; Singh, Anand; Jailwala, Parthav; Lobanov,Alexei; Thomas, Craig J; Ceribelli, Michele; Wilson, Kelli; Ricketts, Christopher J; Vocke, Cathy D; Wells, Catherine; Bottaro, Donald P; Linehan, W Marston; Neckers, Len; Srinivasan, Ramaprasad
  3. Journal of Experimental & Clinical Cancer Research : CR. 2022, Jun 27; 41(1): 208.
  1. 4.   Distribution and Functional Consequences of Somatic MAP2K1 Variants in Affected Skin Associated with Bone Lesions in Melorheostosis
  2. Jha, Smita; Ivovic, Aleksandra; Kang, Heeseog; Meylan, Françoise; Hanson, Eric P; Rimland, Casey; Lange, Eileen; Katz, James; McBride, Alison; Warner,Andrew; Edmondson,Elijah; Cowen, Edward W; Marini, Joan C; Siegel, Richard M; Bhattacharyya, Timothy
  3. Journal of Investigative Dermatology. 2021, Mar; 141(3): 688-692.
  1. 5.   Dabrafenib and Trametinib in Patients With Tumors With BRAFV600E Mutations: Results of the NCI-MATCH Trial Subprotocol H
  2. Salama, April K S; Li, Shuli; Macrae, Erin R; Park, Jong-In; Mitchell, Edith P; Zwiebel, James A; Chen, Helen X; Gray, Robert J; McShane, Lisa M; Rubinstein, Larry V; Patton, David; Williams,Mickey; Hamilton, Stanley R; Armstrong, Deborah K; Conley, Barbara A; Arteaga, Carlos L; Harris, Lyndsay N; O'Dwyer, Peter J; Chen, Alice P; Flaherty, Keith T
  3. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2020, NOV 20; 38(33): JCO2000762.
  1. 6.   Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization
  2. Zhang, Yu; Goto, Masuo; Oda, Akifumi; Hsu, Pei-Ling; Guo, Ling-Li; Fu, Yan-Hui; Morris-Natschke, Susan L.; Hamel,Ernest; Lee, Kuo-Hsiung; Hao, Xiao-Jiang
  3. Molecules (Basel, Switzerland). 2019, Mar 31; 24(7): pii: E1256.
  1. 7.   Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras
  2. Bahr, J. C.; Robey, R. W.; Luchenko, V.; Basseville, A.; Chakraborty, A. R.; Kozlowski, H.; Pauly, G. T.; Patel, P.; Schneider, J. P.; Gottesman, M. M.; Bates, S. E.
  3. Oncotarget. 2016, 13-Sep; 7(43): 69804-69815.
  1. 8.   Physiological levels of virion-associated human immunodeficiency virus type 1 envelope induce coreceptor-dependent calcium flux
  2. Melar, M.; Ott, D. E.; Hope, T. J.
  3. Journal of Virology. 2007, Feb; 81(4): 1773-1785.
  1. 9.   Oncogenic met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling
  2. Mood, K.; Saucier, C.; Ishimura, A.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Journal of Cellular Physiology. 2006, APR; 207(1): 271-285.
  1. 10.   R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells
  2. Cicala, C.; Arthos, J.; Martinelli, E.; Censoplano, N.; Cruz, C. C.; Chung, E.; Selig, S. M.; Van Ryk, D.; Yang, J.; Jagannatha, S.; Chun, T. W.; Ren, P.; Lempicki, R. A.; Fauci, A. S.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, Mar; 103(10): 3746-3751.
  1. 11.   KSR regulation of the Raf-MEK-ERK cascade
  2. Ritt, D. A.; Daar, I. O.; Morrison, D. K.
  3. Regulators and Effectors of Small Gtpases: Ras Family. 2006; 407 : 224-237.
  1. 12.   Suppression of p65 phosphorylation coincides with inhibition of I kappa B alpha polyubiquitination and degradation
  2. Hu, J.; Haseebuddin, M.; Young, M.; Colburn, N. H.
  3. Molecular Carcinogenesis. 2005, DEC; 44(4): 274-284.
  1. 13.   Activation of the Jun N-terminal kinase pathway by friend spleen focus-forming virus and its role in the growth and survival of friend virus-induced erythroleukemia cells
  2. Nishigaki, K.; Hanson, C.; Thompson, D.; Yugawa, T.; Ruscetti, S.
  3. Journal of Virology. 2005, OCT; 79(20): 12752-12762.
  1. 14.   Dendritic cells endocytose Bacillus anthracis spores: Implications for anthrax pathogenesis
  2. Brittingham, K. C.; Ruthel, G.; Panchal, R. G.; Fuller, C. L.; Ribot, W. J.; Hoover, T. A.; Young, H. A.; Anderson, A. O.; Bavari, S.
  3. Journal of Immunology. 2005, MAY 1; 174(9): 5545-5552.
  1. 15.   Regulation of raf-1 by direct feedback phosphorylation
  2. Dougherty, M. K.; Muller, J.; Ritt, D. A.; Zhou, M.; Zhou, X. Z.; Copeland, T. D.; Conrads, T. P.; Veenstra, T. D.; Lu, K. P.; Morrison, D. K.
  3. Molecular Cell. 2005, JAN 21; 17(2): 215-224.
  1. 16.   Involvement of domain II in toxicity of anthrax lethal factor
  2. Liang, X. D.; Young, J. J.; Boone, S. A.; Waugh, D. S.; Duesbery, N. S.
  3. Journal of Biological Chemistry. 2004, DEC 10; 279(50): 52473-52478.
  1. 17.   Contribution of JNK, Mek, Mos and PI-3K signaling to GVBD in Xenopus oocytes
  2. Mood, K.; Bong, Y. S.; Lee, H. S.; Ishimura, A.; Daar, I. O.
  3. Cellular Signalling. 2004, MAY; 16(5): 631-642.
  1. 18.   Regulation of map kinase signaling modules by scaffold proteins in mammals
  2. Morrison, D. K.; Davis, R. J.
  3. Annual Review of Cell and Developmental Biology. 2003 19: 91-118.
  1. 19.   Polo-like kinase is required for the fragmentation of pericentriolar Golgi stacks during mitosis
  2. Sutterlin, C.; Lin, C. Y.; Feng, Y.; Ferris, D. K.; Erikson, R. L.; Malhotra, V.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2001 98(16): 9128-9132.
  1. 20.   A genetic screen for modifiers of a kinase suppressor of ras- dependent rough eye phenotype in drosophila
  2. Therrien, M.; Morrison, D. K.; Wong, A. M.; Rubin, G. M.
  3. Genetics. 2000 156(3): 1231-1242.
  1. 21.   A computer method for predicting the electrophoretic mobility of peptides
  2. Metral, C. J.; Janini, G. M.; Muschik, G. M.; Issaq, H. J.
  3. HRC-Journal of High Resolution Chromatography. 1999 22(7): 373-378.
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