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  1. 1.   A Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft (PDOX) Mouse Model Is Sensitive to Bevacizumab and Vinorelbine, Regressed by Eribulin and Resistant to Olaparib
  2. Yamamoto, Jun; Murata, Takuya; Tashiro, Yoshihiko; Higuchi, Takashi; Sugisawa, Norihiko; Nishino, Hiroto; Inubushi, Sachiko; Sun, Y U; Lim, Hyein; Miyake, Kentaro; Hongo, Atsushi; Nomura, Tsunehisa; Saitoh, Wataru; Moriya, Takuya; Tanino, Hirokazu; Hozumi, Chihiro; Bouvet, Michael; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2509-2514.
  1. 2.   Recombinant Methioninase Combined With Tumor-targeting Salmonella typhimurium A1-R Induced Regression in a PDOX Mouse Model of Doxorubicin-resistant Dedifferentiated Liposarcoma
  2. Igarashi, Kentaro; Kawaguchi, Kei; Zhao, Ming; Han, Qinghong; Tan, Yuying; Kiyuna, Tasuku; Miyake, Kentaro; Higuchi, Takashi; Nelson, Scott D; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2515-2523.
  1. 3.   Comparison of the Efficacy of EGFR Tyrosine Kinase Inhibitors Erlotinib and Low-dose Osimertinib on a PC-9-GFP EGFR Mutant Non-small-cell Lung Cancer Growing in the Brain of Nude Mice
  2. Katsuya, Yuki; Miyake, Kentaro; Higuchi, Takashi; Oshiro, Hiromichi; Sugisawa, Norihiko; Singh,Shree Ram; Goto, Yasushi; Zhao, Ming; Hoffman, Robert M.
  3. In vivo (Athens, Greece). 2020, May-Jun; 34(3): 1027-1030.
  1. 4.   Pazopanib Inhibits Tumor Growth, Lymph-node Metastasis and Lymphangiogenesis of an Orthotopic Mouse of Colorectal Cancer
  2. Zhu, Guangwei; Zhao, Ming; Han, Qinghong; Tan, Yuying; Sun, Yu; Bouvet, Michael; Singh,Shree Ram; Ye, Jianxin; Hoffman, Robert M.
  3. Cancer genomics & proteomics. 2020, Mar-Apr; 17(2): 131-139.
  1. 5.   The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model
  2. Miyake, Kentaro; Higuchi, Takashi; Oshiro, Hiromichi; Zhang, Zhiying; Sugisawa, Norihiko; Park, Jun Ho; Razmjooei, Sahar; Katsuya, Yuki; Barangi, Maryam; Li, Yunfeng; Nelson, Scott D; Murakami, Takashi; Homma, Yuki; Hiroshima, Yukihiko; Matsuyama, Ryusei; Bouvet, Michael; Chawla, Sant P; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2019, SEP; 117: 109093.
  1. 6.   Tumor-targeting Salmonella typhimurium A1-R overcomes nab-paclitaxel resistance in a cervical cancer PDOX mouse model
  2. Miyake, Kentaro; Murata, Takuya; Murakami, Takashi; Zhao, Ming; Kiyuna, Tasuku; Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Masuyo; Lwin, Thinzar M.; Hozumi, Chihiro; Komatsu, Shin; Kikuchi, Takashi; Bouvet, Michael; Shimoya, Koichiro; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M.
  3. Archives of gynecology and obstetrics. 2019, JUN; 299(6): 1683-1690.
  1. 7.   Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model
  2. Igarashi, Kentaro; Kawaguchi, Kei; Kiyuna, Tasuku; Miyake, Kentaro; Miyake, Masuyo; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Higuchi, Takashi; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Tissue & cell. 2019, Jun; 58: 107-111.
  1. 8.   Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model
  2. Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Kawaguchi, Kei; Zhang, Zhiying; Wangsiricharoen, Sintawat; Razmjooei, Sahar; Oshiro, Hiromichi; Higuchi, Takashi; Li, Yunfeng; Nelson, Scott D; Murakami, Takashi; Hiroshima, Yukihiko; Kumamoto, Takafumi; Matsuyama, Ryusei; Bouvet, Michael; Singh, Shree Ram; Chawla, Sant P; Endo, Itaru; Hoffman, Robert M
  3. Biochemical and biophysical research communications. 2019, FEB 19; 509(4): 1041-1046.
  1. 9.   Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model
  2. Miyake, Kentaro; Kiyuna, Tasuku; Li, Shukuan; Han, Qinghong; Tan, Yuying; Zhao, Ming; Oshiro, Hiromichi; Kawaguchi, Kei; Higuchi, Takashi; Zhang, Zhiying; Razmjooei, Sahar; Barangi, Maryam; Wangsiricharoen, Sintawat; Murakami, Takashi; Singh, Arun S.; Li, Yunfeng; Nelson, Scott D.; Eilber, Fritz C.; Bouvet, Michael; Hiroshima, Yukihiko; Chishima, Takashi; Matsuyama, Ryusei; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M.
  3. Chemotherapy. 2019, Feb; 63(5): 278-283.
  1. 10.   The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model
  2. Higuchi, Takashi; Kawaguchi, Kei; Miyake, Kentaro; Oshiro, Hiromichi; Zhang, Zhiying; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Igarashi, Kentaro; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Nelson, Scott D; Dry, Sarah M; Li, Yunfeng; Chawla, Sant P; Eilber, Frederick C; Singh, Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2019, Jan 04; 111: 835-840.
  1. 11.   Tumor-targeting Salmonella typhimurium A1-R overcomes partial carboplatinum-resistance of a cancer of unknown primary (CUP)
  2. Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Zhao, Ming; Wangsiricharoen, Sintawat; Kawaguchi, Kei; Zhang, Zhiying; Higuchi, Takashi; Razmjooei, Sahar; Li, Yunfeng; Nelson, Scott D.; Russell, Tara; Singh, Arun; Murakami, Takashi; Hiroshima, Yukihiko; Momiyama, Masashi; Matsuyama, Ryusei; Chishima, Takashi; Singh,Shree Ram; Chawla, Sant P.; Eilber, Fritz C.; Endo, Itaru; Hoffman, Robert M.
  3. TISSUE & CELL. 2018, OCT; 54: 144-149.
  1. 12.   Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma
  2. Kawaguchi, Kei; Higuchi, Takashi; Li, Shukuan; Han, Qinghong; Tan, Yuying; Igarashi, Kentaro; Zhao, Ming; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Ohshiro, Hiromichi; Sugisawa, Norihiko; Zhang, Zhiying; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Eckardt, Mark A; Singh, Arun S; Singh, Shree Ram; Eilber, Fritz C; Unno, Michiaki; Hoffman, Robert M
  3. Biochemical and Biophysical Research Communications. 2018, Sep 18; 503(4): 3086-3092.
  1. 13.   Patterns of Sensitivity to a Panel of Drugs are highly Individualized for Undifferentiated/Unclassified Soft Tissue Sarcoma (USTS) in Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Models
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Singh, Arun S; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Unno, Michiaki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Journal of drug targeting. 2018, Jul 19; 1-25.
  1. 14.   Recombinant methioninase in combination with DOX overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma
  2. Igarashi, Kentaro; Kawaguchi, Kei; Li, Shukuan; Han, Qinghong; Tan, Yuying; Murakami, Takashi; Kiyuna, Tasuku; Miyake, Kentaro; Miyake, Masuyo; Singh, Arun S; Eckhardt, Mark A; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Tsuchiya, Hiroyuki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Cancer Letters. 2018, MAR 28; 417: 168-173.
  1. 15.   Yin Yang 1 positively regulates BRCA1 and inhibits mammary cancer formation
  2. Lee, M. H.; Lahusen, T.; Wang, R. H.; Xiao, C.; Xu, X.; Hwang, Y. S.; He, W. W.; Shi, Y.; Deng, C. X.
  3. Oncogene. 2012, Jan; 31(1): 116-127.
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