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  1. 1.   The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells
  2. Alexandre, K. B.; Gray, E. S.; Mufhandu, H.; McMahon, J. B.; Chakauya, E.; O'Keefe, B. R.; Chikwamba, R.; Morris, L.
  3. Virology. 2012, Feb; 423(2): 175-186.
  1. 2.   Binding of the Mannose-Specific Lectin, Griffithsin, to HIV-1 gp120 Exposes the CD4-Binding Site
  2. Alexandre, K. B.; Gray, E. S.; Pantophlet, R.; Moore, P. L.; McMahon, J. B.; Chakauya, E.; O'Keefe, B. R.; Chikwamba, R.; Morris, L.
  3. Journal of Virology. 2011, Sep; 85(17): 9039-9050.
  1. 3.   Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate
  2. Kouokam, J. C.; Huskens, D.; Schols, D.; Johannemann, A.; Riedell, S. K.; Walter, W.; Walker, J. M.; Matoba, N.; O'Keefe, B. R.; Palmer, K. E.
  3. Plos One. 2011, Aug; 6(8):
  1. 4.   Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity
  2. Moulaei, T.; Shenoy, S. R.; Giomarelli, B.; Thomas, C.; McMahon, J. B.; Dauter, Z.; O'Keefe, B. R.; Wlodawer, A.
  3. Structure. 2010, Sep; 18(9): 1104-1115.
  1. 5.   Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin
  2. Alexandre, K. B.; Gray, E. S.; Lambson, B. E.; Moore, P. L.; Choge, I. A.; Mlisana, K.; Karim, S. S. A.; McMahon, J.; O'Keefe, B.; Chikwamba, R.; Morris, L.
  3. Virology. 2010, Jun; 402(1): 187-196.
  1. 6.   Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component
  2. O'Keefe, B. R.; Vojdani, F.; Buffa, V.; Shattock, R. J.; Montefiori, D. C.; Bakke, J.; Mirsalis, J.; d'Andrea, A. L.; Hume, S. D.; Bratcher, B.; Saucedo, C. J.; McMahon, J. B.; Pogue, G. P.; Palmer, K. E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(15): 6099-6104.
  1. 7.   Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain
  2. Ahmed, F.; Tessarollo, L.; Thiele, C.; Mocchetti, I.
  3. Brain Research. 2008 1227: 1-11.
  1. 8.   Constitutive expression of human keratin 14 gene in mouse lung induces premalignant lesions and squamous differentiation
  2. Dakir, E.; Feigenbaum, L.; Linnoila, R. I.
  3. Carcinogenesis. 2008 29(12): 2377-2384.
  1. 9.   Brain-derived neurotrophic factor prevents the nigrostriatal degeneration induced by human immunodeficiency virus-1 glycoprotein 120 in vivo
  2. Nosheny, R. L.; Ahmed, F.; Yakovlev, A.; Meyer, E. M.; Ren, K.; Tessarollo, L.; Mocchetti, I.
  3. European Journal of Neuroscience. 2007, Apr; 25(8): 2275-2284.
  1. 10.   Calorimetric investigation of phosphorylated and non-phosphorylated peptide ligand binding to the human Grb7-SH2 domain
  2. Spuches, A. M.; Argiros, H. J.; Lee, K. H.; Haas, L. L.; Perch, S. C.; Krag, D. N.; Roller, P. P.; Wilcox, D. E.; Lyons, B. A.
  3. Journal of Molecular Recognition. 2007, Jul-Aug; 20(4): 245-252.
  1. 11.   Gab1 is required for cell cycle transition, cell proliferation, and transformation induced by an oncogenic Met receptor
  2. Mood, K.; Saucier, C.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Molecular Biology of the Cell. 2006, Sep; 17(9): 3717-3728.
  1. 12.   Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding
  2. Ziolkowska, N. E.; O'Keefe, B. R.; Mori, T.; Zhu, C.; Giomarelli, B.; Vojdani, F.; Palmer, K. E.; McMahon, J. B.; Wlodawer, A.
  3. Structure. 2006, Jul; 14(7): 1127-1135.
  1. 13.   Identification of molecular markers for endometriosis in blood lymphocytes by using deoxyribonucleic acid microarrays
  2. Flores, I.; Rivera, E.; Mousses, S.; Chen, Y. D.; Rozenblum, E.
  3. Fertility and Sterility. 2006, Jun; 85(6): 1676-1683.
  1. 14.   Structural studies of algal lectins with anti-HIV activity
  2. Ziolkowska, N. E.; Wlodawer, A.
  3. Acta Biochimica Polonica. 2006 53(4): 617-626.
  1. 15.   Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A
  2. Witvrouw, M.; Fikkert, V.; Hantson, A.; Pannecouque, C.; O'Keefe, B. R.; McMahon, J.; Stamatatos, L.; De Clercq, E.; Bolmstedt, A.
  3. Journal of Virology. 2005, JUN; 79(12): 7777-7784.
  1. 16.   Genetic recombination of human immunodeficiency virus type 1 in one round of viral replication: Effects of genetic distance, target cells, accessory genes, and lack of high negative interference in crossover events
  2. Rhodes, T. D.; Nikolaitchik, O.; Chen, J. B.; Powell, D.; Hu, W. S.
  3. Journal of Virology. 2005, FEB; 79(3): 1666-1677.
  1. 17.   In silico protein design by combinatorial assembly of protein building blocks
  2. Tsai, H. H.; Tsai, C. J.; Ma, B. Y.; Nussinov, R.
  3. Protein Science. 2004, OCT; 13(10): 2753-2765.
  1. 18.   Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models
  2. Tsai, C. C.; Emau, P.; Jiang, Y. H.; Agy, M. B.; Shattock, R. J.; Schmidt, A.; Morton, W. R.; Gustafson, K. R.; Boyd, M. R.
  3. Aids Research and Human Retroviruses. 2004 20(1): 11-18.
  1. 19.   Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity
  2. Guo, G. L.; Lambert, G.; Negishi, M.; Ward, J. M.; Brewer, H. B.; Kliewer, S. A.; Gonzalez, F. J.; Sinal, C. J.
  3. Journal of Biological Chemistry. 2003 278(46): 45062-45071.
  1. 20.   Encoded fiber-optic microsphere arrays for probing protein- carbohydrate interactions
  2. Adams, E. W.; Ueberfeld, J.; Ratner, D. M.; O'Keefe, B. R.; Walt, D. R.; Seeberger, P. H.
  3. Angewandte Chemie-International Edition. 2003 42(43): 5317-5320.
  1. 21.   Update on D-Ala-Peptide T-Amide (DAPTA): A viral entry inhibitor that blocks CCR5 chemokine receptors
  2. Ruff, M. R.; Polianova, M.; Yang, Q. E.; Leoung, G. S.; Ruscetti, F. W.; Pert, C. B.
  3. Current HIV Research. 2003 1(1): 51-67.
  1. 22.   Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
  2. Botos, I.; O'Keefe, B. R.; Shenoy, S. R.; Cartner, L. K.; Ratner, D. M.; Seeberger, P. H.; Boyd, M. R.; Wlodawer, A.
  3. Journal of Biological Chemistry. 2002 277(37): 34336-34342.
  1. 23.   Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency
  2. Hollander, M. C.; Kovalsky, O.; Salvador, J. M.; Kim, K. E.; Patterson, A. D.; Raines, D. C.; Fornace, A. J.
  3. Cancer Research. 2001 61(6): 2487-2491.
  1. 24.   HIV-inhibitory natural products part 71 - Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner
  2. Bolmstedt, A. J.; O'Keefe, B. R.; Shenoy, S. R.; McMahon, J. B.; Boyd, M. R.
  3. Molecular Pharmacology. 2001 59(5): 949-954.
  1. 25.   Peptide T inhibits HIV-1 infection mediated by the chemokine receptor-5 (CCR5)
  2. Ruff, M. R.; Melendez-Guerrero, L. M.; Yang, Q. E.; Ho, W. Z.; Mikovits, J. W.; Pert, C. B.; Ruscetti, F. A.
  3. Antiviral Research. 2001 52(1): 63-75.
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