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  1. 1.   Structure Guided Design, Synthesis, and Biological Evaluation of Oxetane-Containing Indole Analogues
  2. Ren, Wen; Vairin, Rebecca; Ward, Jacob D; Francis, Ricardo; VanNatta, Jenny; Bai,Ruoli; Tankoano, Pouguiniseli E; Deng, Yuling; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G
  3. Bioorganic & Medicinal Chemistry. 2023, Jun 29; 92: 117400.
  1. 2.   Creation and preclinical evaluation of a novel mussel-inspired, biomimetic, bioactive bone graft scaffold: direct comparison with Infuse bone graft using a rat model of spinal fusion
  2. Cottrill, Ethan; Pennington, Zach; Wolf,Matthew; Dirckx, Naomi; Ehresman, Jeff; Perdomo-Pantoja, Alexander; Rajkovic, Christian; Lin, Jessica; Maestas, David R; Mageau, Ashlie; Lambrechts, Dennis; Stewart, Veronica; Sciubba, Daniel M; Theodore, Nicholas; Elisseeff, Jennifer H; Witham, Timothy
  3. Journal of Neurosurgery. Spine. 2023, Mar 31; 39(1): 113-121.
  1. 3.   Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
  2. Huang, Chen; Chen, Lijun; Savage, Sara R.; Eguez, Rodrigo Vargas; Dou, Yongchao; Li, Yize; Leprevost, Felipe da Veiga; Jaehnig, Eric J.; Lei, Jonathan T.; Wen, Bo; Schnaubelt, Michael; Krug, Karsten; Song, Xiaoyu; Cieslik, Marcin; Chang, Hui-Yin; Wyczalkowski, Matthew A.; Li, Kai; Colaprico, Antonio; Li, Qing Kay; Clark, David J.; Hu, Yingwei; Cao, Liwei; Pan, Jianbo; Wang, Yuefan; Cho, Kyung-Cho; Shi, Zhiao; Liao, Yuxing; Jiang, Wen; Anurag, Meenakshi; Ji, Jiayi; Yoo, Seungyeul; Zhou, Daniel Cui; Liang, Wen-Wei; Wendl, Michael; Vats, Pankaj; Carr, Steven A.; Mani, D. R.; Zhang, Zhen; Qian, Jiang; Chen, Xi S.; Pico, Alexander R.; Wang, Pei; Chinnaiyan, Arul M.; Ketchum, Karen A.; Kinsinger, Christopher R.; Robles, Ana; An, Eunkyung; Hiltke, Tara; Mesri, Mehdi; Thiagarajan,Mathangi; Weaver, Alissa M.; Sikora, Andrew G.; Lubinski, Jan; Wierzbicka, Malgorzata; Wiznerowicz, Maciej; Satpathy, Shankha; Gillette, Michael A.; Miles, George; Ellis, Matthew J.; Omenn, Gilbert S.; Rodriguez, Henry; Boja, Emily S.; Dhanasekaran, Saravana M.; Ding, Li; Nesvizhskii, Alexey; El-Naggar, Adel K.; Chan, Daniel W.; Zhang, Hui; Zhang, Bing
  3. Cancer Cell. 2021, Mar 8; 39(3): 361-379.
  1. 4.   Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
  2. Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen,Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O'Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A.; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H.
  3. Nature Genetics. 2021, Jan; 53(1): 86-99.
  1. 5.   Single cell-derived primary rectal carcinoma cell lines reflect intratumor heterogeneity associated with treatment response
  2. Braun, Rüdiger; Anthuber, Lena; Hirsch, Daniela; Wangsa, Darawalee; Lack,Justin; McNeil, Nicole E; Heselmeyer-Haddad, Kerstin; Torres, Irianna; Wangsa, Danny; Brown, Markus A; Tubbs, Anthony; Auslander, Noam; Gertz, E Michael; Brauer, Philip R; Cam,Maggie; Sackett, Dan; Habermann, Jens K; Nussenzweig, Andre; Ruppin, Eytan; Zhang, Zhongqiu; Rosenberg, Daniel W; Ried, Thomas
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020, JUL; 26(13): 3468-3480.
  1. 6.   Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis
  2. Evrard,Yvonne; Srivastava, Anuj; Randjelovic, Jelena; Consortium, Nci PDXNet; Doroshow, James H; Dean, Dennis A; Morris, Jeffrey S; Chuang, Jeffrey H
  3. Cancer research. 2020, JUN 1; 80(11): 2286-2297.
  1. 7.   Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion
  2. Coomer,Chad; Carlon-Andres, Irene; Iliopoulou, Maro; Dustin, Michael L.; Compeer, Ewoud B.; Compton,Alex; Padilla-Parra, Sergi
  3. PLOS PATHOGENS. 2020, FEB; 16(2):
  1. 8.   Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers
  2. Wilsker,Deborah; Barrett, Allison M.; Dull,Angie; Lawrence,Scott; Hollingshead,Melinda; Chen, Alice; Kummar, Shivaani; Parchment,Ralph; Doroshow, James H.; Kinders,Robert
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019, MAY 15; 25(10): 3084-3095.
  1. 9.   Novel cancer gene variants and gene fusions of triple-negative breast cancers (TNBCs) reveal their molecular diversity conserved in the patient-derived xenograft (PDX) model
  2. Jung, Jaeyun; Jang, Kiwon; Ju, Jung Min; Lee, Eunji; Lee, Jong Won; Kim, Hee Jung; Kim, Jisun; Lee, Sae Byul; Ko, Beom Seok; Son, Byung Ho; Lee, Hee Jin; Gong, Gyungyup; Ahn, Sei Yeon; Choi, Jung Kyoon; Singh, Shree Ram; Chang, Suhwan
  3. Cancer Letters. 2018, Aug 01; 428: 127-138.
  1. 10.   Patterns of Sensitivity to a Panel of Drugs are highly Individualized for Undifferentiated/Unclassified Soft Tissue Sarcoma (USTS) in Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Models
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Singh, Arun S; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Unno, Michiaki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Journal of drug targeting. 2018, Jul 19; 1-25.
  1. 11.   Oncogenic Ras Isoforms Signaling Specificity at the Membrane
  2. Nussinov, Ruth; Tsai, Chung-Jung; Jang, Hyunbum
  3. CANCER RESEARCH. 2018, Feb 1; 78(3): 593-602.
  1. 12.   Comparison of planar, PET and well-counter measurements of total tumor radioactivity in a mouse xenograft model.
  2. Green, Michael V; Seidel, Jurgen; Williams, Mark; Wong, Karen J; Ton, Anita; Basuli, Falguni; Choyke, Peter L; Jagoda, Elaine M
  3. Nuclear medicine and biology. 2017, Oct; 53: 29-36.
  1. 13.   Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay
  2. Ji, Jay; Zhang, Yiping; Redon, Christophe E.; Reinhold, William C.; Chen, Alice P.; Fogli, Laura K.; Holbeck, Susan L.; Parchment, Ralph; Hollingshead, Melinda; Tomaszewski, Joseph E.; Dudon, Quentin; Pommier, Yves; Doroshow, James H.; Bonner, William M.
  3. PLOS ONE. 2017, Feb 3; 12(2): e0171582.
  1. 14.   Cytotoxic Activity of Immunotoxin SS1P Is Modulated by TACE-Dependent Mesothelin Shedding
  2. Zhang, Y. J.; Chertov, O.; Zhang, J. L.; Hassan, R.; Pastan, I.
  3. Cancer Research. 2011, Sep; 71(17): 5915-5922.
  1. 15.   Multihistology, Target-Driven Pilot Trial of Oral Topotecan as an Inhibitor of Hypoxia-Inducible Factor-1 alpha in Advanced Solid Tumors
  2. Kummar, S.; Raffeld, M.; Juwara, L.; Horneffer, Y.; Strassberger, A.; Allen, D.; Steinberg, S. M.; Rapisarda, A.; Spencer, S. D.; Figg, W. D.; Chen, X. H.; Turkbey, I. B.; Choyke, P.; Murgo, A. J.; Doroshow, J. H.; Melillo, G.
  3. Clinical Cancer Research. 2011, Aug; 17(15): 5123-5131.
  1. 16.   Lymphoid-Specific Helicase (HELLS) Is Essential for Meiotic Progression in Mouse Spermatocytes
  2. Zeng, W. X.; Baumann, C.; Schmidtmann, A.; Honaramooz, A.; Tang, L.; Bondareva, A.; Dores, C.; Fan, T.; Xi, S. C.; Geiman, T.; Rathi, R.; de Rooij, D.; De La Fuente, R.; Muegge, K.; Dobrinski, I.
  3. Biology of Reproduction. 2011, Jun; 84(6): 1235-1241.
  1. 17.   Insights into the effect of nitric oxide and its metabolites nitrite and nitrate at inhibiting neointimal hyperplasia
  2. Vavra, A. K.; Havelka, G. E.; Martinez, J.; Lee, V. R.; Fu, B.; Jiang, Q.; Keefer, L. K.; Kibbe, M. R.
  3. Nitric Oxide-Biology and Chemistry. 2011, Jun; 25(1): 22-30.
  1. 18.   Poly(diol-co-citrate)s as Novel Elastomeric Perivascular Wraps for the Reduction of Neointimal Hyperplasia
  2. Serrano, M. C.; Vavra, A. K.; Jen, M.; Hogg, M. E.; Murar, J.; Martinez, J.; Keefer, L. K.; Ameer, G. A.; Kibbe, M. R.
  3. Macromolecular Bioscience. 2011, May; 11(5): 700-709.
  1. 19.   The Role of Lipids in Retrovirus Replication
  2. Waheed, A. A.; Freed, E. O.
  3. Viruses-Basel. 2010, May; 2(5): 1146-1180.
  1. 20.   Tailored synthesis of nitric oxide-releasing polyurethanes using O-2-protected diazeniumdiolated chain extenders
  2. Reynolds, M. M.; Saavedra, J. E.; Showalter, B. M.; Valdez, C. A.; Shanklin, A. P.; Oh, B. K.; Keefer, L. K.; Meyerhoff, M. E.
  3. Journal of Materials Chemistry. 2010, Mar 21; 20(15): 3107-3114.
  1. 21.   Effect of Mutations in the Human Immunodeficiency Virus Type 1 Protease on Cleavage of the gp41 Cytoplasmic Tail
  2. Waheed, A. A.; Ablan, S. D.; Sowder, R. C.; Roser, J. D.; Schaffner, C. P.; Chertova, E.; Freed, E. O.
  3. Journal of Virology. 2010, Mar; 84(6): 3121-3126.
  1. 22.   Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition
  2. Rapisarda, A.; Hollingshead, M.; Uranchimeg, B.; Bonomi, C. A.; Borgel, S. D.; Carter, J. P.; Gehrs, B.; Raffeld, M.; Kinders, R. J.; Parchment, R.; Anver, M. R.; Shoemaker, R. H.; Melillo, G.
  3. Molecular Cancer Therapeutics. 2009 8(7): 1867-1877.
  1. 23.   Incomplete protection against simian immunodeficiency virus vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges
  2. Ambrose, Z.; Compton, L.; Piatak, M.; Lu, D.; Alvord, W. G.; Lubomirski, M. S.; Hildreth, J.; Lifson, J. D.; Miller, C. J.; KewalRamani, V. N.
  3. Journal of Virology. 2008 82(13): 6591-6599.
  1. 24.   Retroviruses Human Immunodeficiency Virus and Murine Leukemia Virus Are Enriched in Phosphoinositides
  2. Chan, R.; Uchil, P. D.; Jin, J.; Shui, G. H.; Ott, D. E.; Mothes, W.; Wenk, M. R.
  3. Journal of Virology. 2008 82(22): 11228-11238.
  1. 25.   Interaction between the human immunodeficiency virus type 1 Gag matrix domain and phosphatidylinositol-(4,5)-bisphosphate is essential for efficient Gag membrane binding
  2. Chukkapalli, V.; Hogue, I. B.; Boyko, V.; Hu, W. S.; Ono, A.
  3. Journal of Virology. 2008 82(5): 2405-2417.
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