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  1. 1.   Acute-phase innate immune responses in SIVmac239-infected Mamu-B*08+ Indian rhesus macaques may contribute to the establishment of elite control
  2. Rosen, Brandon C; Sawatzki, Kaitlin; Ricciardi, Michael J; Smith, Elise; Golez, Inah; Mauter, Jack T; Pedreño-López, Núria; Yrizarry-Medina, Aaron; Weisgrau, Kim L; Vosler, Logan J; Voigt, Thomas B; Louw, Johan J; Tisoncik-Go, Jennifer; Whitmore, Leanne S; Panayiotou, Christakis; Ghosh, Noor; Furlott, Jessica R; Parks, Christopher L; Desrosiers, Ronald C; Lifson,Jeffrey; Rakasz, Eva G; Watkins, David I; Gale, Michael
  3. Frontiers in Immunology. 2024 15: 1478063.
  1. 2.   Natural Killer Cells Regulate Acute SIV Replication, Dissemination, and Inflammation, but Do Not Impact Independent Transmission Events
  2. Woolley, Griffin; Mosher, Matthew; Kroll, Kyle; Jones, Rhianna; Hueber, Brady; Sugawara, Sho; Manickam, Cordelia; Terry, Karen; Varner, Valerie; Lifton, Michelle; Ram, Daniel; Fennessey,Christine; Keele,Brandon; Reeves, R Keith
  3. Journal of Virology. 2022, Dec 13; e0151922.
  1. 3.   Recombinant Herpesvirus Vectors: Durable Immune Responses and Durable Protection against Simian Immunodeficiency Virus SIVmac239 Acquisition
  2. Castro, Isabelle M.; Ricciardi, Michael J.; Gonzalez-Nieto, Lucas; Rakasz, Eva G.; Lifson,Jeffrey; Desrosiers, Ronald C.; Watkins, David; Martins, Mauricio A.
  3. Journal of Virology . 2021, Jun 24; 95(14):
  1. 4.   IL-21 and IFN alpha therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques
  2. Harper, Justin; Huot, Nicolas; Micci, Luca; Tharp, Gregory; King, Colin; Rascle, Philippe; Shenvi, Neeta; Wang, Hong; Galardi, Cristin; Upadhyay, Amit A.; Villinger, Francois; Lifson,Jeffrey; Silvestri, Guido; Easley, Kirk; Jacquelin, Beatrice; Bosinger, Steven; Muller-Trutwin, Michaela; Paiardini, Mirko
  3. Nature communications. 2021, May 17; 12(1):
  1. 5.   Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques
  2. Bochart, Rachele M.; Busman-Sahay, Kathleen; Bondoc, Stephen; Morrow, David W.; Ortiz, Alexandra M.; Fennessey,Christine; Fischer, Miranda B.; Shiel, Oriene; Swanson, Tonya; Shriver-Munsch, Christine M.; Crank, Hugh B.; Armantrout, Kimberly M.; Barber-Axthelm, Aaron M.; Langner, Charlotte; Moats, Cassandra R.; Labriola, Caralyn S.; MacAllister, Rhonda; Axthelm, Michael K.; Brenchley, Jason M.; Keele,Brandon; Estes, Jacob D.; Hansen, Scott G.; Smedley, Jeremy V.
  3. PLoS pathogens. 2021, May 10; 17(5):
  1. 6.   SMAC mimetic plus triple combination bispecific HIVxCD3 DART® molecules in SHIV.C.CH505-infected, ART-suppressed rhesus macaques
  2. Dashti, Amir; Waller, Chevaughn; Mavigner, Maud; Schoof, Nils; Bar, Katharine J; Shaw, George M; Vanderford, Thomas; Liang, Shan; Lifson,Jeffrey; Dunham, Richard M; Ferrari, Guido; Tuyishime, Marina; Lam, Chia-Ying K; Nordstrom, Jeffrey L; Margolis, David M; Silvestri, Guido; Chahroudi, Ann
  3. Journal of virology. 2020, NOV; 94(21): pii: JVI.00793-20..
  1. 7.   Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge
  2. Felber,Barbara; Lu, Zhongyan; Hu, Xintao; Valentin,Antonio; Rosati,Margherita; Remmel, Christopher A L; Weiner, Joshua A; Carpenter, Margaret C; Faircloth, Katelyn; Stanfield-Oakley, Sherry; Williams, Wilton B; Shen, Xiaoying; Tomaras, Georgia D; LaBranche, Celia C; Montefiori, David; Trinh, Hung V; Rao, Mangala; Alam, Munir S; Vandergrift, Nathan A; Saunders, Kevin O; Wang, Yunfei; Rountree, Wes; Das, Jishnu; Alter, Galit; Reed, Steven G; Aye, Pyone P; Schiro, Faith; Pahar, Bapi; Dufour, Jason P; Veazey, Ronald S; Marx, Preston A; Venzon, David J; Shaw, George M; Ferrari, Guido; Ackerman, Margaret E; Haynes, Barton F; Pavlakis,George
  3. Cell reports. 2020, May 12; 31(6): 107624.
  1. 8.   Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies
  2. Pedreno-Lopez, Nuria; Dang, Christine M.; Rosen, Brandon C.; Ricciardi, Michael J.; Bailey, Varian K.; Gutman, Martin J.; Gonzalez-Nieto, Lucas; Pauthner, Matthias G.; Song, Ge; Andrabi, Raiees; Weisgrau, Kim L.; Pomplun, Nicholas; Martinez-Navio, Jose M.; Fuchs, Sebastian P.; Wrammert, Jens; Rakasz, Eva G.; Lifson,Jeffrey; Martins, Mauricio A.; Burton, Dennis R.; Watkins, David; Magnani, Diogo M.
  3. Molecular therapy. Methods & clinical development. 2020, Mar 13; 16: 225-237.
  1. 9.   Simian Immunodeficiency Virus-Infected Memory CD4+ T Cells Infiltrate to the Site of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS
  2. Lee, Cheri A; Beasley, Erin; Sundar, Karthikeyan; Smelkinson, Margery; Vinton, Carol; Deleage,Claire; Matsuda, Kenta; Wu, Fan; Estes, Jake D; Lafont, Bernard A P; Brenchley, Jason M; Hirsch, Vanessa M
  3. mBio. 2020, Mar-Apr; 11(2):
  1. 10.   PD-1 blockade and TLR7 activation lack therapeutic benefit in chronic SIV-infected macaques on antiretroviral therapy
  2. Bekerman, Elena; Hesselgesser, Joseph; Carr, Brian; Nagel, Mark; Hung, Magdeleine; Wang, Adele; Stapleton, Lance; von Gegerfelt, Agneta; Elyard, Hanne Andersen; Lifson,Jeffrey; Geleziunas, Romas
  3. Antimicrobial agents and chemotherapy. 2019, NOV; 63(11): pii: AAC.01163-19.
  1. 11.   Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques
  2. Gonzalez-Nieto, Lucas; Castro, Isabelle M; Bischof, Georg F; Shin, Young C; Ricciardi, Michael J; Bailey, Varian K; Dang, Christine M; Pedreño-Lopez, Nuria; Magnani, Diogo M; Ejima, Keisuke; Allison, David B; Gil, Hwi Min; Evans, David T; Rakasz, Eva G; Lifson,Jeffrey; Desrosiers, Ronald C; Martins, Mauricio A
  3. PLoS pathogens. 2019, Sep 30; 15(9): e1008015.
  1. 12.   Evaluation of an antibody to a4ß7 in the control of SIVmac239-nef-stop infection
  2. Di Mascio, M; Lifson,Jeffrey; Srinivasula,Sharat; Kim,Insook; DeGrange, P; Keele,Brandon; Belli, A J; Reimann, K A; Wang, Y; Proschan, M; Lane, H C; Fauci, A S
  3. Science (New York, N.Y.). 2019, Sep 06; 365(6457): 1025-1029.
  1. 13.   A live-attenuated RhCMV/SIV vaccine shows long-term efficacy against heterologous SIV challenge
  2. Hansen, Scott G; Marshall, Emily E; Malouli, Daniel; Ventura, Abigail B; Hughes, Colette M; Ainslie, Emily; Ford, Julia C; Morrow, David; Gilbride, Roxanne M; Bae, Jin Y; Legasse, Alfred W; Oswald,Kelli; Shoemaker,Rebecca; Berkemeier,Brian; Bosche,Bj; Hull,Mike; Womack, Jennie; Shao, Jason; Edlefsen, Paul T; Reed, Jason S; Burwitz, Ben J; Sacha, Jonah B; Axthelm, Michael K; Früh, Klaus; Lifson,Jeffrey; Picker, Louis J
  3. Science translational medicine. 2019, Jul 17; 11(501): pii: eaaw2607.
  1. 14.   The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08(+) Rhesus Macaques
  2. Martins, Mauricio A.; Gonzalez-Nieto, Lucas; Shin, Young C.; Domingues, Aline; Gutman, Martin J.; Maxwell, Helen S.; Magnani, Diogo M.; Ricciardi, Michael J.; Pedreno-Lopez, Nuria; Bailey, Varian K.; Altman, John D.; Parks, Christopher L.; Allison, David B.; Ejima, Keisuke; Rakasz, Eva G.; Capuano, Saverio; Desrosiers, Ronald C.; Lifson, Jeffrey; Watkins, David
  3. Journal of virology. 2019, Feb 19; 93
  1. 15.   Nonhuman primate models of human viral infections
  2. Estes, Jake; Wong, Scott W.; Brenchley, Jason M.
  3. NATURE REVIEWS IMMUNOLOGY. 2018, Jun; 18(6): 390-404.
  1. 16.   The frequency of alpha(4)beta(7)(high) memory CD4(+) T cells correlates with susceptibility to rectal simian immunodeficiency virus infection
  2. Martinelli, E.; Veglia, F.; Goode, D.; Guerra-Perez, N.; Aravantinou, M.; Arthos, J.; Piatak, M., Jr.; Lifson, J. D.; Blanchard, J.; Gettie, A.; Robbiani, M.
  3. Journal of acquired immune deficiency syndromes (1999). 2013, 1-Dec; 64(4): 325-31.
  1. 17.   SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses
  2. Lai, L. L.; Kwa, S. F.; Kozlowski, P. A.; Montefiori, D. C.; Nolen, T. L.; Hudgens, M. G.; Johnson, W. E.; Ferrari, G.; Hirsch, V. M.; Felber, B. K.; Pavlakis, G. N.; Earl, P. L.; Moss, B.; Amara, R. R.; Robinson, H. L.
  3. Vaccine. 2012, Feb; 30(9): 1737-1745.
  1. 18.   PATHOLOGIC LESIONS IN CHIMPANZEES (PAN TROGYLODYTES SCHWEINFURTHII) FROM GOMBE NATIONAL PARK, TANZANIA, 2004-2010
  2. Terio, K. A.; Kinsel, M. J.; Raphael, J.; Mlengeya, T.; Lipende, I.; Kirchhoff, C. A.; Gilagiza, B.; Wilson, M. L.; Kamenya, S.; Estes, J. D.; Keele, B. F.; Rudicell, R. S.; Liu, W. M.; Patton, S.; Collins, A.; Hahn, B. H.; Travis, D. A.; Lonsdorf, E. V.
  3. Journal of Zoo and Wildlife Medicine. 2011, Dec; 42(4): 597-607.
  1. 19.   Depletion of CD4(+) T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques
  2. Ortiz, A. M.; Klatt, N. R.; Li, B.; Yi, Y.; Tabb, B.; Hao, X. P.; Sternberg, L.; Lawson, B.; Carnathan, P. M.; Cramer, E. M.; Engram, J. C.; Little, D. M.; Ryzhova, E.; Gonzalez-Scarano, F.; Paiardini, M.; Ansari, A. A.; Ratcliffe, S.; Else, J. G.; Brenchley, J. M.; Collman, R. G.; Estes, J. D.; Derdeyn, C. A.; Silvestri, G.
  3. Journal of Clinical Investigation. 2011, Nov; 121(11): 4433-4445.
  1. 20.   Functional Cure of SIVagm Infection in Rhesus Macaques Results in Complete Recovery of CD4(+) T Cells and Is Reverted by CD8(+) Cell Depletion
  2. Pandrea, I.; Gaufin, T.; Gautam, R.; Kristoff, J.; Mandell, D.; Montefiori, D.; Keele, B. F.; Ribeiro, R. M.; Veazey, R. S.; Apetrei, C.
  3. Plos Pathogens. 2011, Aug; 7(8): 15.
  1. 21.   TCR triggering transcriptionally downregulates CCR5 expression on rhesus macaque CD4(+) T-cells with no measurable effect on susceptibility to SIV infection
  2. Minang, J. T.; Trivett, M. T.; Barsov, E. V.; Del Prete, G. Q.; Trubey, C. M.; Thomas, J. A.; Gorelick, R. J.; Piatak, M.; Ott, D. E.; Ohlen, C.
  3. Virology. 2011, Jan; 409(1): 132-140.
  1. 22.   XMRV: A New Virus in Prostate Cancer?
  2. Aloia, A. L.; Sfanos, K. S.; Isaacs, W. B.; Zheng, Q. Z.; Maldarelli, F.; De Marzo, A. M.; Rein, A.
  3. Cancer Research. 2010, Dec; 70(24): 10028-10033.
  1. 23.   Molecular Architectures of Trimeric SIV and HIV-1 Envelope Glycoproteins on Intact Viruses: Strain-Dependent Variation in Quaternary Structure
  2. White, T. A.; Bartesaghi, A.; Borgnia, M. J.; Meyerson, J. R.; de la Cruz, M. J. V.; Bess, J. W.; Nandwani, R.; Hoxie, J. A.; Lifson, J. D.; Milne, J. L. S.; Subramaniam, S.
  3. Plos Pathogens. 2010, Dec; 6(12): 14.
  1. 24.   Determinants of Protection among HIV-Exposed Seronegative Persons: An Overview
  2. Lederman, M. M.; Alter, G.; Daskalakis, D. C.; Rodriguez, B.; Sieg, S. F.; Hardy, G.; Cho, M.; Anthony, D.; Harding, C.; Weinberg, A.; Silverman, R. H.; Douek, D. C.; Margolis, L.; Goldstein, D. B.; Carrington, M.; Goedert, J. J.
  3. Journal of Infectious Diseases. 2010, Nov; 202: S333-S338.
  1. 25.   A Tonsillar PolyICLC/AT-2 SIV Therapeutic Vaccine Maintains Low Viremia Following Antiretroviral Therapy Cessation
  2. Vagenas, P.; Aravantinou, M.; Williams, V. G.; Jasny, E.; Piatak, M.; Lifson, J. D.; Salazar, A. M.; Blanchard, J. L.; Gettie, A.; Robbiani, M.
  3. Plos One. 2010, Sep; 5(9): 13.
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