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  1. 1.   Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel Site
  2. Calvo, E.; Barasoain, I.; Matesanz, R.; Pera, B.; Camafeita, E.; Pineda, O.; Hamel, E.; Vanderwal, C. D.; Andreu, J. M.; Lopez, J. A.; Diaz, J. F.
  3. Biochemistry. 2012, Jan; 51(1): 329-341.
  1. 2.   The Assembly-Inducing Laulimalide/Peloruside A Binding Site on Tubulin: Molecular Modeling and Biochemical Studies with [H-3]Peloruside A
  2. Nguyen, T. L.; Xu, X. M.; Gussio, R.; Ghosh, A. K.; Hamel, E.
  3. Journal of Chemical Information and Modeling. 2010, Nov; 50(11): 2019-2028.
  1. 3.   Natural product scaffolds as leads-to drugs
  2. Newman, D. J.; Cragg, G. M.
  3. Future Medicinal Chemistry. 2009, Nov; 1(8): 1415-1427.
  1. 4.   Synergistic effects of peloruside a and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly
  2. Hamel, E.; Day, B. W.; Miller, J. H.; Jung, M. K.; Northcote, P. T.; Ghosh, A. K.; Curran, D. P.; Cushman, M.; Nicolaou, K. C.; Paterson, I.; Sorensen, E. J.
  3. Molecular Pharmacology. 2006, Nov; 70(5): 1555-1564.
  1. 5.   Natural products from marine invertebrates and microbes as modulators of antitumor targets
  2. Newman, D. J.; Cragg, G. M.
  3. Current Drug Targets. 2006, MAR; 7(3): 279-304.
  1. 6.   CB694, a novel antimitotic with antitumor activities
  2. Weiderhold, K. N.; Randall-Hiubek, D. A.; Polin, L. A.; Hamel, E.; Mooberry, S. L
  3. International Journal of Cancer. 2006, FEB 15; 118(4): 1032-1040.
  1. 7.   A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel
  2. Dabydeen, D. A.; Florence, G. J.; Paterson, I.; Hamel, E.
  3. Cancer Chemotherapy and Pharmacology. 2004 53(5): 397-403.
  1. 8.   Evaluation of antimitotic agents by quantitative comparisons of their effects on the polymerization of purified tubulin
  2. Hamel, E.
  3. Cell Biochemistry and Biophysics. 2003 38(1): 1-21.
  1. 9.   Mother nature's combinatorial libraries; their influence on the synthesis of drugs
  2. Kingston, D. G. I.; Newman, D. J.
  3. Current Opinion in Drug Discovery & Development. 2002 5(2): 304-316.
  1. 10.   A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells
  2. Giannakakou, P.; Gussio, R.; Nogales, E.; Downing, K. H.; Zaharevitz, D.; Bollbuck, B.; Poy, G.; Sackett, D.; Nicolaou, K. C.; Fojo, T.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2000 97(6): 2904-2909.
  1. 11.   The coral-derived natural products eleutherobin and sarcodictyins A and B: Effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site
  2. Hamel, E.; Sackett, D. L.; Vourloumis, D.; Nicolaou, K. C.
  3. Biochemistry. 1999 38(17): 5490-5498.
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