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  1. 1.   Genotypic Resistance at Viral Rebound Among Patients Who Received Lopinavir/Ritonavir-Based or Efavirenz-Based First Antiretroviral Therapy in South Africa
  2. Dlamini, J. N.; Hu, Z. H.; Ledwaba, J.; Morris, L.; Maldarelli, F. M.; Dewar, R. L.; Highbarger, H. C.; Somaroo, H.; Sangweni, P.; Follmann, D. A.; Pau, A. K.; Phidisa, I. I. S. T.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2011, Nov; 58(3): 304-308.
  1. 2.   The effects of RNase H inhibitors and nevirapine on the susceptibility of HIV-1 to AZT and 3TC
  2. Davis, C. A.; Parniak, M. A.; Hughes, S. H.
  3. Virology. 2011, Oct; 419(2): 64-71.
  1. 3.   Phenotypic characterization of drug resistance-associated mutations in HIV-1 RT connection and RNase H domains and their correlation with thymidine analogue mutations
  2. Lengruber, R. B.; Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Baumann, J.; Santos, A. F.; Pathak, V. K.; Soares, M. A.
  3. Journal of Antimicrobial Chemotherapy. 2011, Apr; 66(4): 702-708.
  1. 4.   Synthesis and biological evaluation of novel dihydro-aryl/alkylsulfanyl-cyclohexylmethyl-oxopyrimidines (S-DACOs) as high active anti-HIV agents
  2. He, Y. P.; Long, J.; Zhang, S. S.; Li, C.; Lai, C. C.; Zhang, C. S.; Li, D. X.; Zhang, D. H.; Wang, H.; Cai, Q. Q.; Zheng, Y. T.
  3. Bioorganic & Medicinal Chemistry Letters. 2011, Jan; 21(2): 694-697.
  1. 5.   An Antiretroviral/Zinc Combination Gel Provides 24 Hours of Complete Protection against Vaginal SHIV Infection in Macaques
  2. Kenney, J.; Aravantinou, M.; Singer, R.; Hsu, M.; Rodriguez, A.; Kizima, L.; Abraham, C. J.; Menon, R.; Seidor, S.; Chudolij, A.; Gettie, A.; Blanchard, J.; Lifson, J. D.; Piatak, M.; Fernandez-Romero, J. A.; Zydowsky, T. M.; Robbiani, M.
  3. Plos One. 2011, Jan; 6(1): 10.
  1. 6.   Design and Synthesis of Isonucleosides Constructed on a 2-Oxa-6-thiabicyclo[3.2.0]heptane Scaffold
  2. Yoshimura, Y.; Asami, K.; Imamichi, T.; Okuda, T.; Shiraki, K.; Takahata, H.
  3. Journal of Organic Chemistry. 2010, Jun; 75(12): 4161-4171.
  1. 7.   Optimization of allele-specific PCR using patient-specific HIV consensus sequences for primer design
  2. Boltz, V. F.; Maldarelli, F.; Martinson, N.; Morris, L.; McIntyre, J. A.; Gray, G.; Hopley, M. J.; Kimura, T.; Mayers, D. L.; Robinson, P.; Mellors, J. W.; Coffin, J. M.; Palmer, S. E.
  3. Journal of Virological Methods. 2010, Mar; 164(1-2): 122-126.
  1. 8.   Synthesis of conformationally locked carbocyclic nucleoside phosphonates to probe the active site of HIV-1 RT
  2. Saneyoshi, H.; Vu, B. C.; Hughes, S. H.; Boyer, P. L.; Sarafianos, S. G.; Marquez, V. E.
  3. Nucleic acids symposium series (2004). 2008 (52): 623-4.
  1. 9.   Mitochondrial DNA haplogroups influence AIDS progression
  2. Hendrickson, S. L.; Hutcheson, H. B.; Ruiz-Pesini, E.; Poole, J. C.; Lautenberger, J.; Sezgin, E.; Kingsley, L.; Goedert, J. J.; Vlahov, D.; Donfield, S.; Wallace, D. C.; O'Brien, S. J.
  3. Aids. 2008 22(18): 2429-2439.
  1. 10.   Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age
  2. Divi, R. L.; Leonard, S. L.; Walker, B. L.; Kuo, M. M.; Shockley, M. E.; St Claire, M. C.; Nagashima, K.; Harbaugh, S. W.; Harbaugh, J. W.; Poirier, M. C.
  3. Toxicological Sciences. 2007, Sep; 99(1): 203-213.
  1. 11.   Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to zidovudine
  2. Divi, R. L.; Haverkos, K. J.; Humsi, J. A.; Shockley, M. E.; Thamire, C.; Nagashima, K.; Olivero, O. A.; Poirier, M. C.
  3. Environmental and Molecular Mutagenesis. 2007, Apr-May; 48(3-4): 179-189.
  1. 12.   New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: Synthesis, resolution, and inhibitory activity
  2. Krajewski, K.; Zhang, Y. J.; Parrish, D.; Deschamps, J.; Roller, P. P.; Pathak, V. K.
  3. Bioorganic & Medicinal Chemistry Letters. 2006, Jun; 16(11): 3034-3038.
  1. 13.   Crystallography and the design of anti-AIDS drugs: Conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors
  2. Das, K.; Lewi, P. J.; Hughes, S. H.; Arnold, E.
  3. Progress in Biophysics and Molecular Biology. 2005, JUN; 88(2): 209-231.
  1. 14.   Panel of prototypical infectious molecular HIV-1 clones containing multiple nucleoside reverse transcriptase inhibitor resistance mutations
  2. Johnston, E.; Dupnik, K. M.; Gonzales, M. J.; Winters, M. A.; Rhee, S. Y.; Imamichi, T.; Shafer, R. W.
  3. Aids. 2005, APR 29; 19(7): 731-733.
  1. 15.   Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: Balance between RNase H activity and nucleotide excision
  2. Nikolenko, G. N.; Palmer, S.; Maldarelli, F.; Mellors, J. W.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, FEB 8; 102(6): 2093-2098.
  1. 16.   In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques
  2. Ambrose, Z.; Boltz, V.; Palmer, S.; Coffin, J. M.; Hughes, S. H.; KewalRamani, V. N.
  3. Journal of Virology. 2004, DEC; 78(24): 13553-13561.
  1. 17.   Infectious transmission and replication of human T-cell leukemia virus type 1
  2. Derse, D.; Heidecker, G.; Mitchell, M.; Hill, S.; Lloyd, P.; Princler, G.
  3. Frontiers in Bioscience. 2004, SEP 1; 9: 2495-2499.
  1. 18.   Mutations in HIV-1 RNase H domain confer high-level resistance to nucleoside reverse transcriptase inhibitors and provide novel insights into the mechanism of nucleotide excision-mediated drug resistance
  2. Nikolenko, G. N.; Palmer, S.; Maldarelli, F.; Mellors, J. W.; Coffin, J. M.; Pathak, V. K.
  3. Antiviral Therapy. 2004, AUG; 9(4): U35-U36.
  1. 19.   Action of Anti-HIV drugs and resistance: Reverse transcriptase inhibitors and protease inhibitors
  2. Imamichi, T.
  3. Current Pharmaceutical Design. 2004 10(32): 4039-4053.
  1. 20.   Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants
  2. Das, K.; Clark, A. D.; Lewi, P. J.; Heeres, J.; de Jonge, M. R.; Koymans, L. M. H.; Vinkers, H. M.; Daeyaert, F.; Ludovici, D. W.; Kukla, M. J.; De Corte, B.; Kavash, R. W.; Ho, C. Y.; Ye, H.; Lichtenstein, M. A.; Andries, K.; Pauwels, R.; de Bethune, M. P.; Boyer, P. L.; Clark, P.; Hughes, S. H.; Janssen, P. A. J.; Arnold, E.
  3. Journal of Medicinal Chemistry. 2004 47(10): 2550-2560.
  1. 21.   Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir
  2. Divi, R. L.; Walker, V. E.; Wade, N. A.; Nagashima, K.; Seilkopf, S. K.; Adams, M. E.; Nesel, C. J.; O'Neill, J. P.; Abrams, E. J.; Poirier, M. C.
  3. Aids. 2004 18(7): 1013-1021.
  1. 22.   Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
  2. Tuske, S.; Sarafianos, S. G.; Clark, A. D.; Ding, J. P.; Naeger, L. K.; White, K. L.; Miller, M. D.; Gibbs, C. S.; Boyer, P. L.; Clark, P.; Wang, G.; Gaffney, B. L.; Jones, R. A.; Jerina, D. M.; Hughes, S. H.; Arnold, E.
  3. Nature Structural & Molecular Biology. 2004 11(5): 469-474.
  1. 23.   Structural and biochemical mechanisms of HIV-1 RT drug resistance
  2. Boyer, P. L.; Gao, H. Q.; Serafianos, S.; Ding, J.; Clark, P.; Clark, A.; Arnold, E.; Hughes, S. H.
  3. Conference on Retroviruses and Opportunistic Infections. 1999, 218 (abstract no. S33).
  1. 24.   2'-Fluoro-2',3'-Dideoxyarabinosyladenine (F-Dda) - Activity Against Drug-Resistant Human Immunodeficiency Virus Strains and Clades a-E
  2. Driscoll, J. S.; Mayers, D. L.; Bader, J. P.; Weislow, O. S.; Johns, D. G.; Buckheit, R. W.
  3. Antiviral Chemistry & Chemotherapy. 1997 8(2): 107-111.
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