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  1. 1.   UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth
  2. Wolfe, Andrew L; Zhou, Qingwen; Toska, Eneda; Galeas, Jacqueline; Ku, Angel A; Koche, Richard P; Bandyopadhyay, Sourav; Scaltriti, Maurizio; Lebrilla, Carlito B; McCormick, Frank; Kim, Sung Eun
  3. Proceedings of the National Academy of Sciences of the United States of America. 2021, Aug 03; 118(31):
  1. 2.   Crystal structure of UDP-glucose pyrophosphorylase from Yersinia pestis, a potential therapeutic target against plague
  2. Gibbs, Morgan E; Lountos,George; Gumpena, Rajesh; Waugh,David
  3. Acta crystallographica. Section F, Structural biology communications. 2019, Sep 01; 75(Pt 9): 608-615.
  1. 3.   Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer
  2. Tang, W.; Fu, Y. P.; Figueroa, J. D.; Malats, N.; Garcia-Closas, M.; Chatterjee, N.; Kogevinas, M.; Baris, D.; Thun, M.; Hall, J. L.; De Vivo, I.; Albanes, D.; Porter-Gill, P.; Purdue, M. P.; Burdett, L.; Liu, L. Y.; Hutchinson, A.; Myers, T.; Tardon, A.; Serra, C.; Carrato, A.; Garcia-Closas, R.; Lloreta, J.; Johnson, A.; Schwenn, M.; Karagas, M. R.; Schned, A.; Black, A.; Jacobs, E. J.; Diver, W. R.; Gapstur, S. M.; Virtamo, J.; Hunter, D. J.; Fraumeni, J. F.; Chanock, S. J.; Silverman, D. T.; Rothman, N.; Prokunina-Olsson, L.
  3. Human Molecular Genetics. 2012, Apr; 21(8): 1918-1930.
  1. 4.   The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2
  2. Pasek, M.; Ramakrishnan, B.; Boeggeman, E.; Mercer, N.; Dulcey, A. E.; Griffiths, G. L.; Qasba, P. K.
  3. Glycobiology. 2012, Mar; 22(3): 379-388.
  1. 5.   A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
  2. Rothman, N.; Garcia-Closas, M.; Chatterjee, N.; Malats, N.; Wu, X. F.; Figueroa, J. D.; Real, F. X.; Van den Berg, D.; Matullo, G.; Baris, D.; Thun, M.; Kiemeney, L. A.; Vineis, P.; De Vivo, I.; Albanes, D.; Purdue, M. P.; Rafnar, T.; Hildebrandt, M. A. T.; Kiltie, A. E.; Cussenot, O.; Golka, K.; Kumar, R.; Taylor, J. A.; Mayordomo, J. I.; Jacobs, K. B.; Kogevinas, M.; Hutchinson, A.; Wang, Z. W.; Fu, Y. P.; Prokunina-Olsson, L.; Burdett, L.; Yeager, M.; Wheeler, W.; Tardon, A.; Serra, C.; Carrato, A.; Garcia-Closas, R.; Lloreta, J.; Johnson, A.; Schwenn, M.; Karagas, M. R.; Schned, A.; Andriole, G.; Grubb, R.; Black, A.; Jacobs, E. J.; Diver, W. R.; Gapstur, S. M.; Weinstein, S. J.; Virtamo, J.; Cortessis, V. K.; Gago-Dominguez, M.; Pike, M. C.; Stern, M. C.; Yuan, J. M.; Hunter, D. J.; McGrath, M.; Dinney, C. P.; Czerniak, B.; Chen, M.; Yang, H. S.; Vermeulen, S. H.; Aben, K. K.; Witjes, J. A.; Makkinje, R. R.; Sulem, P.; Besenbacher, S.; Stefansson, K.; Riboli, E.; Brennan, P.; Panico, S.; Navarro, C.; Allen, N. E.; Bueno-De-Mesquita, H. B.; Trichopoulos, D.; Caporaso, N.; Landi, M. T.; Canzian, F.; Ljungberg, B.; Tjonnel, A.; Clavel-Chapelon, F.; Bishop, D. T.; Teo, M. T. W.; Knowles, M. A.; Guarrera, S.; Polidoro, S.; Ricceri, F.; Sacerdote, C.; Allione, A.; Cancel-Tassin, G.; Selinski, S.; Hengstler, J. G.; Dietrich, H.; Fletcher, T.; Rudnai, P.; Gurzau, E.; Koppova, K.; Bolick, S. C. E.; Godfrey, A.; Xu, Z. L.; Sanz-Velez, J. I.; Garcia-Prats, M. D.; Sanchez, M.; Valdivia, G.; Porru, S.; Benhamou, S.; Hoover, R. N.; Fraumeni, J. F.; Silverman, D. T.; Chanock, S. J.
  3. Nature Genetics. 2010, Nov; 42(11): 978-U98.
  1. 6.   Structure-based evolutionary relationship of glycosyltransferases: a case study of vertebrate beta 1,4-galactosyltransferase, invertebrate beta 1,4-N-acetylgalactosaminyltransferase and alpha-polypeptidyl-N-acetylgalactosaminyltransferase
  2. Ramakrishnan, B.; Qasba, P. K.
  3. Current Opinion in Structural Biology. 2010, Oct; 20(5): 536-542.
  1. 7.   Deoxygenated Disaccharide Analogs as Specific Inhibitors of beta 1-4-Galactosyltransferase 1 and Selectin-mediated Tumor Metastasis
  2. Brown, J. R.; Yang, F.; Sinha, A.; Ramakrishnan, B.; Tor, Y.; Qasba, P. K.; Esko, J. D.
  3. Journal of Biological Chemistry. 2009 284(8): 4952-4959.
  1. 8.   Multiple Site-Specific in Vitro Labeling of Single-Chain Antibody
  2. Ramakrishnan, B.; Boeggeman, E.; Manzoni, M.; Zhu, Z. Y.; Loomis, K.; Puri, A.; Dimitrov, D. S.; Qasba, P. K.
  3. Bioconjugate Chemistry. 2009 20(7): 1383-1389.
  1. 9.   Pharmacokinetics, pharmacodynamics and drug metabolism - Characterization of in vitro and in vivo metabolic pathways of the investigational anticancer agent, 2-methoxyestradiol
  2. Lakhani, N. J.; Sparreboom, A.; Xu, X.; Veenstra, T. D.; Venitz, J.; Dahut, W. L.; Figg, W. D.
  3. Journal of Pharmaceutical Sciences. 2007, Jul; 96(7): 1821-1831.
  1. 10.   Oligosaccharide preferences of beta 1,4-galactosyltransferase-I: Crystal structures of Met340His mutant of human beta 1,4-galactosyltransferase-I with a pentasaccharide and trisaccharides of the N-glycan moiety
  2. Ramasamy, V.; Ramakrishnan, B.; Boeggeman, E.; Ratner, D. M.; Seeberger, P. H.; Qasba, P. K.
  3. Journal of Molecular Biology. 2005, OCT 14; 353(1): 53-67.
  1. 11.   Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase I
  2. Ramakrishnan, B.; Boeggeman, E.; Qasba, P. K.
  3. Biochemistry. 2005, MAR 8; 44(9): 3202-3210.
  1. 12.   Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: Crystal structure of the Met344His mutant in complex with chitobiose
  2. Ramakrishnan, B.; Boeggeman, E.; Qasba, P. K.
  3. Biochemistry. 2004, OCT 5; 43(39): 12513-12522.
  1. 13.   Structure and catalytic cycle of beta-1,4-galactosyltransferase
  2. Ramakrishnan, B.; Boeggeman, E.; Ramasamy, V.; Qasba, P. K.
  3. Current Opinion in Structural Biology. 2004, OCT; 14(5): 593-600.
  1. 14.   2-substitution of adenine nucleotide analogues containing a bicyclo 3.1.0 hexane ring system locked in a northern conformation: Enhanced potency as P2Y(1) receptor antagonists
  2. Kim, H. S.; Ohno, M.; Xu, B.; Kim, H. O.; Choi, Y. S.; Ji, X. D.; Maddileti, S.; Marquez, V. E.; Harden, T. K.; Jacobson, K. A.
  3. Journal of Medicinal Chemistry. 2003 46(23): 4974-4987.
  1. 15.   Clinical pharmacology of flavopiridol following a 72-hour continuous infusion
  2. Rudek, M. A.; Bauer, K. S.; Lush, R. M.; Stinson, S. F.; Senderowicz, A. M.; Headlee, D. J.; Arbuck, S. G.; Cox, M. C.; Murgo, A. J.; Sausville, E. A.; Figg, W. D.
  3. Annals of Pharmacotherapy. 2003 37(10): 1369-1374.
  1. 16.   The role of tryptophan 314 in the conformational changes of beta 1,4-galactosyltransferase-I
  2. Ramasamy, V.; Ramakrishnan, B.; Boeggeman, E.; Qasba, P. K.
  3. Journal of Molecular Biology. 2003 331(5): 1065-1076.
  1. 17.   Studies on the metal binding sites in the catalytic domain of beta 1,4-galactosyltransferase
  2. Boeggeman, E.; Qasba, P. K.
  3. Glycobiology. 2002 12(7): 395-407.
  1. 18.   beta-1,4-galactosyltransferase and lactose synthase: Molecular mechanical devices
  2. Ramakrishnan, B.; Boeggeman, E.; Qasba, P. K.
  3. Biochemical and Biophysical Research Communications. 2002 291(5): 1113-1118.
  1. 19.   Crystal structure of beta 1,4-galactosyltransferase complex with UDP-Gal reveals an oligosaccharide acceptor binding site
  2. Ramakrishnan, B.; Balaji, P. V.; Qasba, P. K.
  3. Journal of Molecular Biology. 2002 318(2): 491-502.
  1. 20.   Crystal structure of RNA 3 '-terminal phosphate cyclase, a ubiquitous enzyme with unusual topology
  2. Palm, G. J.; Billy, E.; Filipowicz, W.; Wlodawer, A.
  3. Structure with Folding & Design. 2000 8(1): 13-23.
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