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Using Biological Materials in Animals

The NIH Guidelines require IBC review of experiments involving whole animals in which the animal's genome has been altered by stable introduction of recombinant DNA, or DNA derived therefrom, into the germ-line (transgenic animals) and experiments involving viable recombinant DNA-modified microorganisms tested on whole animals. In addition the IBC is responsible for reviewing animal experiments that involve, but are not limited to, the introduction of: rDNA/RNA, RNAi (shRNA/siRNA), Biological Toxins, Oncogenes, and Pathogens.

If you are ONLY breeding animals, you only need to complete and submit the Breeding Only Form. All other biological research involving animals must be included as part of the registration form.

Breeding/Strain Form (formerly Supplemental Strain Form) - This form is used in conjuction with your animal research if you are breeding and/or generating new strains OR obtaining strains from other PI's to use for your own research purposes.

Submit a new registry, an amendment or a renewal to NCI-Frederick IBC

NOTE: For faster processing, submit all forms electronically (as Word documents) with the exception of signature sheets. Once signed, they can be faxed to 301-846-6619 or emailed to the address above as a PDF.

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