Any investigator needing to transport animals between the NCI-NCI-Frederick and the NIH Bethesda Campus must have a relevant and approved NCI Animal Study Proposal (ASP) with both the NCI-Frederick ACUC and the NCI-Bethesda ACUC. Animals may not be transported between these two locations until the ASP is approved by both ACUCs, except in the case of Bethesda animals needing to be generated, implanted, quarantined or rederived at NCI-Frederick, where approved ASPs already exist.
The completed ASP must describe the animal use activities to be conducted at each site with a clear description of the objectives, the rationale for animal use, the number justification, etc. The same information can be submitted to both ACUCs for review if the experimental section clearly describes the procedures that are to be performed in each location, animal holding facility, laboratory, etc. and identifies the responsible individuals. The transportation details must also be outlined in the ASP.
The NCI-Frederick and the NIH Bethesda Campus (including NCI) are relatively independent, covered by different assurance statements with the Office of Laboratory Animal Welfare and are reviewed, site visited, and assessed as distinct animal programs by the AAALAC International. The completed ASP must describe the animal use activities to be conducted at each site with a clear description of the objectives, the rationale for animal use, the number justification, etc. Each ACUC is required to oversee activities occurring at their location.