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Imaging and Nanotechnology

The Imaging and Nanotechnology Group is headed by Scott McNeil and consists of three laboratories: Electron Microscopy Laboratory, Optical Microscopy And Analysis Laboratory, and Nanotechnology Characterization Laboratory.

Electron Microscopy Laboratory provides expertise in:

  • Transmission Electron Microscopy including ultrastructure analysis, virus particle identification, and negative staining.
  • Scanning Electron Microscopy including EDS microanalysis, low voltage imaging, and microenviroment control for customized imaging.
  • Cryo Electron Microscopy for aiding in the analysis of 3D morphology.
  • Consultation in designing custom protocols, sample processing and embedding, and operational training is available.

Optical Microscopy And Analysis Laboratory provides the following services:

  • Light Microscopy including fluorescent, inverted, and stereo LM.
  • Confocal Microscopy including bright-field, phase, FRAP, FRET, and time-lapse imaging of live cells.
  • Image Analysis including deconvolution, quantification of structural and molecular properties, and measurement of the spatial organization of cells within tissue.
  • Training is available for the confocal microscopes.

Nanotechnology Characterization Laboratory provides expertise in:

  • Physical and chemical characterization of nanomaterials including size, size distribution, surface charge, zeta potential, purity, stability, and elemental analysis.
  • In vitro characterization of nanomaterials including blood contact properties, sterility, general toxicity, molecular mechanisms causing toxicity, and immunotoxicity.
  • In vivo characterization of nanomaterials for identifying parameters related to absorption, distribution, metabolism, excretion, and toxicity profiles.

Page last updated January 18, 2011 @ 10:42 am