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What’s New at the OMAL

The OMAL collaborates closely with NCI investigators as well as engages in technology development.  The publications below highlight some of  these activities.

NEWS: OMAL is now hosting selected in-house developed software resources at OMAL Software and Data Repository.


Cukierski WJ, Nandy K, Gudla P, Meaburn KJ, Misteli T, Foran DJ, Lockett SJ, Ranked Retrieval of Segmented Nuclei For Objective Assessment of Cancer Gene Repositioning, BMC Bioinformatics,  Sep 12;13(1):232, 2012

Nandy K, Gudla PR, Amundsen R, Meaburn KJ, Misteli T, Lockett SJ, Automatic Segmentation and Supervised Learning-based Selection of Nuclei in Cancer Tissue Images, Cytometry A. , Sep;81(9):743-54, 2012

Woldemichael GM, Turbyville TJ, Vasselli JR, Linehan WM, McMahon JB, Lack of a Functional VHL Gene Product Sensitizes Renal Cell Carcinoma Cells to the Apoptotic Effects of the Protein Synthesis Inhibitor Verrucarin A., Neoplasia. Aug;14(8):771-7, 2012

Woldemichael GM, Turbyville TJ, Linehan WM, McMahon JB, Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells, Cancer Res. , Jan 1;71(1):134-42,2011.

Van Prooyen N, Gold H, Andresen V, Schwartz O, Jones K, Ruscetti F, Lockett S, Gudla P, Venzon D, Franchini G:  Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission. Proc Natl Acad Sci USA, Nov 30;107(48):20738-43, 2010.

Johnson-Lyles DN, Peifley K, Lockett S, Neun BW, Hansen M, Clogston J, Stern ST, McNeil SE. Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction.  Toxicol Appl Pharmacol, 1;248(3):249-58, 2010.

Turbyville TJ, Gursel D, Tuskan RG, Walrath JC, Locket S, Wiemer, DF, Beutler JA, Reilly K:  Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and Neurofibromatosis type 1 tumor cells in a NF1 GRD dependent manner.   Mol Cancer Ther, 9(5):1234-43, 2010.

Checkley MA, Nagashima K, Lockett SJ, Nyswaner KM, Garfinkel DJ:  P-body components are required for Ty1 retrotransposition during assembly of retrotransposition-competent virus-like particles. Mol Cell Biol, 30(2):382-98, 2010.

Page last updated September 26, 2012 @ 10:09 am