SPR biosensors offer many advantages over traditional technologies (such as ELISA or Radio-Immuno Assays) for characterizing antibody-antigen interactions. No reagents need to be labeled. Molecular complex formation can be followed in real time and binding kinetics derived. Using affinity reagents, monoclonal antibodies can be captured directly from tissue culture supernants for analysis.
In PCL the following services are available for characterizing antibody-antigen interactions:
- Antibody-antigen binding affinity measurement
- Specific concentration measurement of antibodies