Skip NavigationSkip to Content
Return Return to Search Results

Chromosome painting reveals that galagos have highly derived karyotypes

  1. Author:
    Stanyon, R.
    Koehler, U.
    Consigliere, S.

  2. Author Address

    NCI, Genet Branch, Comparat Mol Cytogenet Sect, Canc Res Ctr, Bldg 560,Room 11-74A, Frederick, MD 21702 USA NCI, Genet Branch, Comparat Mol Cytogenet Sect, Canc Res Ctr, Frederick, MD 21702 USA Ctr Med Genet, MGZ, D-80335 Munich, Germany Univ Genoa, Dept Anthropol Sci, I-16126 Genoa, Italy Stanyon R NCI, Genet Branch, Comparat Mol Cytogenet Sect, Canc Res Ctr, Bldg 560,Room 11-74A, Frederick, MD 21702 USA
    1. Year: 2002
  2. Journal: American Journal of Physical Anthropology
    1. 117
    2. 4
    3. Pages: 319-326
  4. Type of Article: Article
  1. Abstract:

    The differences in chromosome number between Otolemur crassicaudatus (2n = 62) and Galago moholi (2n = 38) are dramatic. However, the total number of signals given by hybridizing human chromosome paints to galago metaphases is similar: 42 in O. crassicaudatus and 38 G. moholi. Many human chromosome homologs are found fragmented in each species, and numerous translocations have resulted in chromosomal syntenies or hybridization associations which differ from those found in humans. Only 7 human autosomes showed conserved synteny in O. crassicaudatus, and 9 in G. moholi. Both galago species have numerous associations or syntenies not found in humans: O. crassicaudatus has 11, and G. moholi has 21. The phylogenetic line leading to the last common ancestor of the two galago species accumulated 6 synapomorphic fissions and 5 synapomorphic fusions. Since the divergence of the two galago species, 10 Robertsonian translocations have further transformed the G. moholi karyotype, and 2 fissions have been incorporated into the O. crassicaudatus karyotype. Comparison with other primates, tree shrews, and other mammals shows that both galagos have karyotypes which are a mixture of derived and conserved chromosomes, and neither has a karyotype close to that of the proposed ancestor of all primates. Published 2002 Wiley-Liss Inc.(dagger)

    See More

  1. Keywords:

External Sources

  1. No sources found.

Library Notes

  1. No notes added.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel