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Mapping of 53 loci in american mink (Mustela vison)

  1. Author:
    Kuznetsov, S. B.
    Matveeva, N. M.
    Murphy, W. J.
    O'Brien, S. J.
    Serov, O. L.

  2. Author Address

    Inst Cytol & Genet, Lab Dev Genet, Novosibirsk 90, Russia Inst Cytol & Genet, Lab Dev Genet, Novosibirsk 90, Russia NCI, Lab Genom Divers, Frederick Canc Res & Dev Ctr, Frederick, MD 21702 USA Univ Fed Rio de Janeiro, Inst Biophys, Rio De Janeiro, Brazil Serov OL Inst Cytol & Genet, Lab Dev Genet, Novosibirsk 90, Russia
    1. Year: 2003
  2. Journal: Journal of Heredity
    1. 94
    2. 5
    3. Pages: 386-391
  4. Type of Article: Article
  1. Abstract:

    Fifty-three genes were mapped in the American mink genome using polymerase chain reaction (PCR)-based analysis of a Chinese hamster-American mink somatic cell hybrid panel. Heterologous primers designed for cat gene mapping were used in this study. Forty-nine of these loci were localized into expected chromosome regions according to Zoo-FISH data, whereas four loci-ALPL, CDC20, ERF-2, and Fc(Mv)23617-were mapped out of expected conserved regions. PCR products amplified with primers corresponding to these four markers were partly sequenced and verified using BLAST. The results showed the homology to be more than 90% between mink and human or cat counterparts. At present, the gene map of American mink has expanded to 127 loci.

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