Skip NavigationSkip to Content
Return Return to Search Results

Tuberculosis: from prehistory to Robert Koch, as revealed by ancient DNA

  1. Author:
    Donoghue, H. D.
    Spigelman, M.
    Greenblatt, C. L.
    Lev-Maor, G.
    Bar-Gal, G. K.
    Matheson, C.
    Vernon, K.
    Nerlich, A. G.
    Zink, A. R.

  2. Author Address

    Univ Coll London, Ctr Infect Dis & Int Hlth, London W1T 4JF, England. Hebrew Univ Jerusalem, Hadassah Med Sch, Kuvin Ctr Study Infect & Trop Dis, IL-91010 Jerusalem, Israel. NCI, Lab Genom Divers, Frederick, MD 21701 USA. Lakehead Univ, Paleo DNA Lab, Fac Sci & Environm Studies, Thunder Bay, ON P7B 5E1, Canada. Univ Queensland, Dept Zool, Brisbane, Qld, Australia. Acad Teaching Hosp, Div Palaeopathol, Inst Pathol, Munich, Germany Donoghue, HD, Univ Coll London, Ctr Infect Dis & Int Hlth, 46 Cleveland St, London W1T 4JF, England
    1. Year: 2004
    2. Date: SEP
  2. Journal: Lancet Infectious Diseases
    1. 4
    2. 9
    3. Pages: 584-592
  4. Type of Article: Review
  1. Abstract:

    During the past 10 years palaeomicrobiology, a new scientific discipline, has developed. The study of ancient pathogens by direct detection of their DNA has answered several historical questions and shown changes to pathogens over time. However, ancient DNA (aDNA) continues to be controversial and great care is needed to provide valid data. Here we review the most successful application of the technology, which is the study of tuberculosis. This has provided direct support for the current theory of Mycobacterium tuberculosis evolution, and suggests areas of investigation for the interaction of M tuberculosis with its host

    See More

  1. Keywords:

External Sources

  1. View Full Text
  2. DOI: 10.1016/S1473-3099(04)01133-8
  3. No sources found.

Library Notes

  1. No notes added.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel