Skip NavigationSkip to Content
Return Return to Search Results

Crystal structure of the Yersinia type III secretion protein YscE

  1. Author:
    Phan, J.
    Austin, B. P.
    Waugh, D. S.

  2. Author Address

    Natl Canc Inst Frederick, Ctr Canc Res, Macromol Crystallog Lab, Frederick, MD 21702 USA Waugh, DS, Natl Canc Inst Frederick, Ctr Canc Res, Macromol Crystallog Lab, POB B, Frederick, MD 21702 USA
    1. Year: 2005
    2. Date: OCT
  2. Journal: Protein Science
    1. 14
    2. 10
    3. Pages: 2759-2763
  4. Type of Article: Article
  1. Abstract:

    The plague-causing bacterium Yersinia pestis utilizes a contact-dependent (type III) secretion system (T3SS) to transport virulence factors from the bacterial cytosol directly into the interior of mammalian cells where they interfere with signal transduction pathways that mediate phagocytosis and the inflammatory response. The type III secretion apparatus is composed of 20-25 different Yersinia secretion (Ysc) proteins. We report here the structure of YscE, the smallest Ysc protein, which is a dimer in solution. The probable mode of oligomerization is discussed

    See More

  1. Keywords:

External Sources

  1. View record in Web of Science®
  2. WOS: 000232233400027

Library Notes

  1. No notes added.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel