Skip NavigationSkip to Content
Return Return to Search Results

High Throughput Screening of Normal and Neoplastic Tissue Samples

  1. Author:
    Erickson, H. S.
    Gannot, G.
    Tangrea, M. A.
    Chuaqui, R. F.
    Gillespie, J. W.
    Emmert-Buck, M. R.

  2. Author Address

    [Gillespie, John W.] NCI, SAIC Frederick Inc, Frederick, MD 21702 USA. [Erickson, Heidi S.; Gannot, Gallya; Tangrea, Michael A.; Chuaqui, Rodrigo F.; Emmert-Buck, Michael R.] NCI, Pathogenet Unit, Pathol Lab, NIH, Bethesda, MD 20892 USA. [Erickson, Heidi S.; Gannot, Gallya; Tangrea, Michael A.; Chuaqui, Rodrigo F.; Emmert-Buck, Michael R.] NCI, Urol Oncol Branch, NIH, Bethesda, MD 20892 USA. [Erickson, Heidi S.] Univ Texas MD Anderson Canc Ctr, Dept Thorac Head & Neck Med Oncol, Thorac Mol Pathol Lab, Houston, TX 77030 USA. [Tangrea, Michael A.] NCI, Tumor Angiogenesis Sect, Surg Branch, NIH, Bethesda, MD 20892 USA.;Gillespie, JW, NCI, SAIC Frederick Inc, Frederick, MD 21702 USA.;jgill1230@gmail.com
    1. Year: 2010
    2. Date: Mar
  2. Journal: Combinatorial Chemistry & High Throughput Screening
    1. 13
    2. 3
    3. Pages: 253-267
  4. Type of Article: Article
  5. ISSN: 1386-2073
  1. Abstract:

    The capacity to rapidly and efficiently elucidate a reliable set of disease specific biomarkers is paramount to enable a future of personalized medicine. High throughput screening methods applied to human clinical samples for the discovery of diagnostic, prognostic, and therapeutic targets address this need. Although the ability to analyze either thousands of markers from one sample or one marker from thousands of samples is the current state of high throughput screening, it would be ideal to have the ability to analyze thousands of markers from thousands of samples to expedite the early discovery phase of biomarkers and their validation. This review summarizes the current state of high throughput screening of tissue specimens and discusses its applications. In addition, the rationale, difficulties, strategies, and development of new technologies to address the need for improved high throughput capabilities are discussed.

    See More

  1. Keywords:

External Sources

  1. View record in Web of Science®
  2. WOS: 000275505200004

Library Notes

  1. Fiscal Year: FY2009-2010
NCI at FrederickClose Button

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel