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  1. 1.   Blind prediction of noncanonical RNA structure at atomic accuracy
  2. Watkins, Andrew M.; Geniesse, Caleb; Kladwang, Wipapat; Zakrevsky, Paul; Jaeger, Luc; Das, Rhiju
  3. Science Advances. 2018, May 25; 4(5): eaar5316.
  1. 2.   Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase
  2. Ndongwe, T. P.; Adedeji, A. O.; Michailidis, E.; Ong, Y. T.; Hachiya, A.; March, B.; Ryan, E. M.; Rai, D. K.; Kirby, K. A.; Whatley, A. S.; Burke, D. H.; Johnson, M.; Ding, S. L.; Zheng, Y. M.; Liu, S. L.; Kodama, E. I.; Delviks-Frankenberry, K. A.; Pathak, V. K.; Mitsuya, H.; Parniak, M. A.; Singh, K.; Sarafianos, S. G.
  3. Nucleic Acids Research. 2012, Jan; 40(1): 345-359.
  1. 3.   The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes
  2. Bintu, L.; Kopaczynska, M.; Hodges, C.; Lubkowska, L.; Kashlev, M.; Bustamante, C.
  3. Nature Structural & Molecular Biology. 2011, Dec; 18(12): 1394-U112.
  1. 4.   Small Molecule Inhibitors as Countermeasures for Botulinum Neurotoxin Intoxication
  2. Li, B.; Peet, N. P.; Butler, M. M.; Burnett, J. C.; Moir, D. T.; Bowlin, T. L.
  3. Molecules. 2011, Jan; 16(1): 202-220.
  1. 5.   Photo- and Biophysical Studies of Lectin-Conjugated Fluorescent Nanoparticles Reduced Sensitivity in High Density Assays
  2. Wang, Y. Q.; Gildersleeve, J. C.; Basu, A.; Zimmt, M. B.
  3. Journal of Physical Chemistry B. 2010, Nov; 114(45): 14487-14494.
  1. 6.   Reverse transcriptase in motion: Conformational dynamics of enzyme-substrate interactions
  2. Gotte, M.; Rausch, J. W.; March, B.; Sarafianos, S.; Le Grice, S. F. J.
  3. Biochimica Et Biophysica Acta-Proteins and Proteomics. 2010, May; 1804(5): 1202-1212.
  1. 7.   The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage site
  2. Abram, M. E.; Sarafianos, S. G.; Parniak, M. A.
  3. Retrovirology. 2010, Feb; 7: 9.
  1. 8.   Revisiting Plus-Strand DNA Synthesis in Retroviruses and Long Terminal Repeat Retrotransposons: Dynamics of Enzyme: Substrate Interactions
  2. Fabris, D.; Marino, J. P.; Le Grice, S. F. J.
  3. Viruses-Basel. 2009, Dec; 1(3): 657-677.
  1. 9.   Structure of HIV-1 Reverse Transcriptase with the Inhibitor beta-Thujaplicinol Bound at the RNase H Active Site
  2. Himmel, D. M.; Maegley, K. A.; Pauly, T. A.; Bauman, J. D.; Das, K.; Dharia, C.; Clark, A. D.; Ryan, K.; Hickey, M. J.; Love, R. A.; Hughes, S. H.; Bergqvist, S.; Arnold, E.
  3. Structure. 2009 17(12): 1625-1635.
  1. 10.   Reaction Mechanism of Glutamate Carboxypeptidase II Revealed by Mutagenesis, X-ray Crystallography, and Computational Methods
  2. Klusak, V.; Barinka, C.; Plechanovova, A.; Mlcochova, P.; Konvalinka, J.; Rulisek, L.; Lubkowski, J.
  3. Biochemistry. 2009 48(19): 4126-4138.
  1. 11.   Identifying and Characterizing a Functional HIV-1 Reverse Transcriptase-binding Site on Integrase
  2. Wilkinson, T. A.; Januszyk, K.; Phillips, M. L.; Tekeste, S. S.; Zhang, M.; Miller, J. T.; Le Grice, S.; Clubb, R. T.; Chow, S. A.
  3. Journal of Biological Chemistry. 2009 284(12): 7931-7936.
  1. 12.   Dynamic binding orientations direct activity of HIV reverse transcriptase
  2. Abbondanzieri, E. A.; Bokinsky, G.; Rausch, J. W.; Zhang, J. X.; Le Grice, S.; Zhuang, X. W.
  3. Nature. 2008 453(7192): 184-189.
  1. 13.   Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design
  2. Bauman, J. D.; Das, K.; Ho, W. C.; Baweja, M.; Himmel, D. M.; Clark, A. D.; Oren, D. A.; Boyer, P. L.; Hughes, S. H.; Shatkin, A. J.; Arnold, E.
  3. Nucleic Acids Research. 2008 36(15): 5083-5092.
  1. 14.   Examining the ribonuclease H primer grip of HIV-1 reverse transcriptase by charge neutralization of RNA/DNA hybrids
  2. Dash, C.; Scarth, B. J.; Badorrek, C.; Gotte, M.; Le Grice, S.
  3. Nucleic Acids Research. 2008 36(20): 6363-6371.
  1. 15.   Structural and Functional Analysis of the E. coli NusB-S10 Transcription Antitermination Complex
  2. Luo, X.; Hsiao, H. H.; Bubunenko, M.; Weber, G.; Court, D. L.; Gottesman, M. E.; Urlaub, H.; Wahl, M. C.
  3. Molecular Cell. 2008 32(6): 791-802.
  1. 16.   Mutations in the U5 region adjacent to the primer binding site affect tRNA cleavage by human immunodeficiency virus type 1 reverse transcriptase in vivo
  2. Oh, J.; McWilliams, M. J.; Julias, J. G.; Hughes, S. H.
  3. Journal of Virology. 2008 82(2): 719-727.
  1. 17.   DNA bending in transcription initiation
  2. Tchernaenko, V.; Radlinska, M.; Lubkowska, L.; Halvorson, H. R.; Kashlev, M.; Lutter, L. C.
  3. Biochemistry. 2008 47(7): 1885-1895.
  1. 18.   An HIV RNase H inhibitory 1,3,4,5-tetragalloylapiitol from the African plant Hylodendron gabunensis
  2. Takada, K.; Bermingham, A.; O'Keefe, B. R.; Wamiru, A.; Beutler, J. A.; Le Grice, S. F. J.; Lloyd, J.; Gustafson, K. R.; McMahon, J. B.
  3. Journal of Natural Products. 2007, Oct; 70(10): 1647-1649.
  1. 19.   HIV-1 protease dimer interface mutations that compensate for viral reverse transcriptase instability in infectious virions
  2. Olivares, I.; Mulky, A.; Boross, P. I.; Tozser, J.; Kappes, J. C.; Lopez-Galindez, C.; Menendez-Arias, L.
  3. Journal of Molecular Biology. 2007, Sep; 372(2): 369-381.
  1. 20.   Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3 '-azido-3 '-dideoxythymidine
  2. Brehm, J. H.; Koontz, D.; Meteer, J. D.; Pathak, V.; Sluis-Cremer, N.; Mellors, J. W.
  3. Journal of Virology. 2007, Aug; 81(15): 7852-7859.
  1. 21.   Mutations in human immunodeficiency virus type 1 RNase H primer grip enhance 3-Azido-3'-deoxythymidine resistance
  2. Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Barr, R.; Pathak, V. K.
  3. Journal of Virology. 2007, Jul; 81(13): 6837-6845.
  1. 22.   Analysis of amino acids in the beta 7-beta 8 loop of human immunodeficiency virus type 1 reverse transcriptase for their role in virus replication
  2. Mulky, A.; Vu, B. C.; Conway, J. A.; Hughes, S. H.; Kappes, J. C.
  3. Journal of Molecular Biology. 2007, Feb; 365(5): 1368-1378.
  1. 23.   EMatch: Discovery of high resolution structural homologues of protein domains in intermediate resolution cryo-EM maps
  2. Lasker, K.; Dror, O.; Shatsky, M.; Nussinov, R.; Wolfson, H. J.
  3. Ieee-Acm Transactions on Computational Biology and Bioinformatics. 2007, Jan-Mar; 4(1): 28-39.
  1. 24.   EMatch: an efficient method for aligning atomic resolution subunits into intermediate-resolution cryo-EM maps of large macromolecular assemblies
  2. Dror, O.; Lasker, K.; Nussinov, R.; Wolfson, H.
  3. Acta Crystallographica Section D-Biological Crystallography. 2007, Jan; 63: 42-49.
  1. 25.   Exploiting structurally diverse nucleoside analogs as probes of reverse transcription complexes
  2. Rausch, J. W.; Le Grice, S. F. J.
  3. Current HIV Research. 2007, Jan; 5(1): 11-22.
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