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  1. 1.   The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome
  2. McDermott, D. H.; Liu, Q.; Ulrick, J.; Kwatemaa, N.; Anaya-O'Brien, S.; Penzak, S. R.; Oliveira, J.; Priel, D. A. L.; Kelly, C.; Garofalo, M.; Littel, P.; Marquesen, M. M.; Hilligoss, D.; DeCastro, R.; Fleisher, T. A.; Kuhns, D. B.; Malech, H. L.; Murphy, P. M.
  3. Blood. 2011, Nov; 118(18): 4957-4962.
  1. 2.   The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling
  2. Ping, Y. F.; Yao, X. H.; Jiang, J. Y.; Zhao, L. T.; Yu, S. C.; Jiang, T.; Lin, M. C. M.; Chen, J. H.; Wang, B.; Zhang, R.; Cui, Y. H.; Qian, C.; Wang, J. M.; Bian, X. W.
  3. Journal of Pathology. 2011, Jul; 224(3): 344-354.
  1. 3.   Neurotrophins modulate the expression of chemokine receptors in the brain
  2. Avdoshina, V. A. V.; Becker, J.; Campbell, L. A.; Parsadanian, M.; Mhyre, T.; Tessarollo, L.; Mocchetti, I.
  3. Journal of Neurovirology. 2011, Feb; 17(1): 58-62.
  1. 4.   Novel Peptides Based on HIV-1 gp120 Sequence with Homology to Chemokines Inhibit HIV Infection in Cell Culture
  2. Chertov, O.; Zhang, N.; Chen, X.; Oppenheim, J. J.; Lubkowski, J.; McGrath, C.; Sowder, R. C.; Crise, B. J.; Malyguine, A.; Kutzler, M. A.; Steele, A. D.; Henderson, E. E.; Rogers, T. J.
  3. Plos One. 2011, Jan 11; 6(1): 10.
  1. 5.   Antiangiogenic agents and HIF-1 inhibitors meet at the crossroads
  2. Rapisarda, A.; Shoemaker, R. H.; Melillo, G.
  3. Cell Cycle. 2009, Dec; 8(24): 4040-4043.
  1. 6.   Photo-activation of the hydrophobic probe iodonaphthylazide in cells alters membrane protein function leading to cell death
  2. Viard, M.; Garg, H.; Blumenthal, R.; Raviv, Y.
  3. BMC Cell Biology. 2009 10 AR 21
  1. 7.   Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain
  2. Ahmed, F.; Tessarollo, L.; Thiele, C.; Mocchetti, I.
  3. Brain Research. 2008 1227: 1-11.
  1. 8.   Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival
  2. Bian, X. W.; Yang, S. X.; Chen, L. H.; Ping, Y. F.; Zhou, X. D.; Wang, Q. L.; Jiang, X. F.; Gong, W. H.; Xiao, H. L.; Du, L. L.; Chen, Z. Q.; Zhao, W.; Shi, L. Q.; Wang, J. M.
  3. Neurosurgery. 2007, Sep; 61(3): 570-578.
  1. 9.   The anti-cancer compound Nordy inhibits CXCR4-mediated production of IL-8 and VEGF by malignant human glioma cells
  2. Ping, Y. F.; Yao, X. H.; Chen, J. H.; Liu, H.; Chen, D. L.; Zhou, X. D.; Wang, J. M.; Bian, X. W.
  3. Journal of Neuro-Oncology. 2007, Aug; 84(1): 21-29.
  1. 10.   CCR4-expressing T cell tumors can be specifically controlled via delivery of toxins to chemokine receptors
  2. Baatar, D.; Olkhanud, P.; Newton, D.; Sumitomo, K.; Biragyn, A.
  3. Journal of Immunology. 2007, Aug; 179(3): 1996-2004.
  1. 11.   Brain-derived neurotrophic factor prevents the nigrostriatal degeneration induced by human immunodeficiency virus-1 glycoprotein 120 in vivo
  2. Nosheny, R. L.; Ahmed, F.; Yakovlev, A.; Meyer, E. M.; Ren, K.; Tessarollo, L.; Mocchetti, I.
  3. European Journal of Neuroscience. 2007, Apr; 25(8): 2275-2284.
  1. 12.   Physiological levels of virion-associated human immunodeficiency virus type 1 envelope induce coreceptor-dependent calcium flux
  2. Melar, M.; Ott, D. E.; Hope, T. J.
  3. Journal of Virology. 2007, Feb; 81(4): 1773-1785.
  1. 13.   Increased efficacy of HIV-1 neutralization by antibodies at low CCR5 surface concentration
  2. Choudhry, V.; Zhang, M. Y.; Harris, I.; Sidorov, I. A.; Vu, B.; Dimitrov, A. S.; Fouts, T.; Dimitrov, D. S.
  3. Biochemical and Biophysical Research Communications. 2006, Sep; 348(3): 1107-1115.
  1. 14.   HIV gp41-induced apoptosis is mediated by caspase-3-dependent mitochondrial depolarization, which is inhibited by HIV protease inhibitor nelfinavir
  2. Garg, H.; Blumenthal, R.
  3. Journal of Leukocyte Biology. 2006, Feb; 79(2): 351-362.
  1. 15.   Risk for HIV-1 infection associated with a common CXCL12 (SDF1) polymorphism and CXCR4 variation in an African population
  2. Petersen, D. C.; Glashoff, R. H.; Shrestha, S.; Bergeron, J.; Laten, A.; Gold, B.; van Rensburg, E. J.; Dean, M.; Hayes, V. M.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2005, DEC 15; 40(5): 521-526.
  1. 16.   Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study
  2. Modi, W. S.; Scott, K.; Goedert, J. J.; Vlahov, D.; Buchbinder, S.; Detels, R.; Donfield, S.; O'Brien, S. J.; Winkler, C.
  3. Genes and Immunity. 2005, DEC; 6(8): 691-698.
  1. 17.   Sphingolipids: Modulators of HIV-1 infection and pathogenesis
  2. Rawat, S. S.; Johnson, B. T.; Puri, A.
  3. Bioscience Reports. 2005, OCT; 25(5-6): 329-343.
  1. 18.   Regulation of human immunodeficiency virus type 1 envelope glycoprotein fusion by a membrane-interactive domain in the gp41 cytoplasmic tail
  2. Wyss, S.; Dimitrov, A. S.; Baribaud, F.; Edwards, T. G.; Blumenthal, R.; Hoxie, J. A.
  3. Journal of Virology. 2005, OCT; 79(19): 12231-12241.
  1. 19.   Marked structural and functional heterogeneity in CXCR4: Separation of HIV-1 and SDF-I alpha responses
  2. Sloane, A. J.; Raso, V.; Dimitrov, D. S.; Xiao, X. D.; Deo, S.; Muljadi, N.; Restuccia, D.; Turville, S.; Kearney, C.; Broder, C. C.; Zoellner, H.; Cunningham, A. L.; Bendall, L.; Lynch, G. W.
  3. Immunology and Cell Biology. 2005 83(2): 129-143.
  1. 20.   Alterations in mast cell function and survival following in vitro infection with human immunodeficiency viruses-1 through CXCR4
  2. Taub, D. D.; Mikovits, J. A.; Nilsson, G.; Schaffer, E. M.; Key, M. L.; Petrow-Sadowski, C.; Ruscetti, F. W.
  3. Cellular Immunology. 2004, AUG; 230(2): 65-80.
  1. 21.   Chemotaxis and calcium responses of phagocytes to formyl peptide receptor ligands is differentially regulated by cyclic ADP ribose
  2. Partida-Sanchez, S.; Iribarren, P.; Moreno-Garcia, M. E.; Gao, X. L.; Murphy, P. M.; Oppenheimer, N.; Wang, J. M.; Lund, F. E.
  3. Journal of Immunology. 2004 172(3): 1896-1906.
  1. 22.   An inhibitor of glycosphingolipid metabolism blocks HIV-1 infection of primary T-cells
  2. Puri, A.; Rawat, S. S.; Lin, H. M. J.; Finnegan, C. A.; Mikovits, J.; Ruscetti, F. W.; Blumenthal, R.
  3. Aids. 2004 18(6): 849-858.
  1. 23.   Functional expression of CD4, CXCR4, and CCR5 in glycosphingolipid-deficient mouse melanoma GM95 cells and susceptibility to HIV-1 envelope glycoprotein-triggered membrane fusion
  2. Rawat, S. S.; Eaton, J.; Gallo, S. A.; Martin, T. D.; Ablan, S.; Ratnayake, S.; Viard, M.; KewalRamani, V. N.; Wang, J. M.; Blumenthal, R.; Puri, A.
  3. Virology. 2004 318(1): 55-65.
  1. 24.   Improved breadth and potency of an HIV-1-neutralizing human single-chain antibody by random mutagenesis and sequential antigen panning
  2. Zhang, M. Y.; Shu, Y. U.; Rudolph, D.; Prabakaran, P.; Labrijn, A. F.; Zwick, M. B.; Lal, R. B.; Dimitrov, D. S.
  3. Journal of Molecular Biology. 2004 335(1): 209-219.
  1. 25.   Regulation of the chemokine receptor CXCR4 by hypoxia
  2. Schioppa, T.; Uranchimeg, B.; Saccani, A.; Biswas, S. K.; Doni, A.; Rapisarda, A.; Bernasconi, S.; Saccani, S.; Nebuloni, M.; Vago, L.; Mantovani, A.; Melillo, G.; Sica, A.
  3. Journal of Experimental Medicine. 2003 198(9): 1391-1402.
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