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  1. 1.   Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers
  2. Nussinov,Ruth; Jang,Hyunbum; Tsai,Chung-Jung; Cheng, Feixiong
  3. PLoS computational biology. 2019, Mar; 15(3):
  1. 2.   Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2
  2. Ramonet, D.; Daher, J. P. L.; Lin, B. M.; Stafa, K.; Kim, J.; Banerjee, R.; Westerlund, M.; Pletnikova, O.; Glauser, L.; Yang, L. C.; Liu, Y.; Swing, D. A.; Beal, M. F.; Troncoso, J. C.; McCaffery, J. M.; Jenkins, N. A.; Copeland, N. G.; Galter, D.; Thomas, B.; Lee, M. K.; Dawson, T. M.; Dawson, V. L.; Moore, D. J.
  3. Plos One. 2011, Apr; 6(4):
  1. 3.   Implications for Gene Therapy-Limiting Expression of IL-2R gamma(c) Delineate Differences in Signaling Thresholds Required for Lymphocyte Development and Maintenance
  2. Orr, S. J.; Roessler, S.; Quigley, L.; Chan, T.; Ford, J. W.; O'Connor, G. M.; McVicar, D. W.
  3. Journal of Immunology. 2010, Aug; 185(3): 1393-1403.
  1. 4.   Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo
  2. Daniel, J. A.; Pellegrini, M.; Lee, J. H.; Paull, T. T.; Feigenbaum, L.; Nussenzweig, A.
  3. Journal of Cell Biology. 2008 183(5): 777-783.
  1. 5.   CDK2 is required by MYC to induce apoptosis
  2. Deb-Basu, D.; Aleem, E.; Kaldis, P.; Felsher, D. W.
  3. Cell Cycle. 2006, Jun; 5(12): 1342-1347.
  1. 6.   Oncogenic met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling
  2. Mood, K.; Saucier, C.; Ishimura, A.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Journal of Cellular Physiology. 2006, APR; 207(1): 271-285.
  1. 7.   Friend spleen focus-forming virus transforms rodent fibroblasts in cooperation with a short form of the receptor tyrosine kinase Stk
  2. Nishigaki, K.; Hanson, C.; Jelacic, T.; Thompson, D.; Ruscetti, S.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, OCT 25; 102(43): 15488-15493.
  1. 8.   Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: Molecular targets are TBK1 and RIP1 in TRIF complex
  2. Youn, H. S.; Lee, J. Y.; Fitzgerald, K. A.; Young, H. A.; Akira, S.; Hwang, D. H.
  3. Journal of Immunology. 2005, SEP 1; 175(5): 3339-3346.
  1. 9.   Autophosphorylation of Archaeoglobus fulgidus Rio2 and crystal structures of its nucleotide-metal ion complexes
  2. Laronde-Leblanc, N.; Guszczynski, T.; Copeland, T.; Wlodawer, A.
  3. Febs Journal. 2005, JUN; 272(11): 2800-2810.
  1. 10.   Cutting edge: Expression of IL-1 receptor-associated kinase-4 (IRAK-4) proteins with mutations identified in a patient with recurrent bacterial infections alters normal IRAK-4 interaction with components of the IL-1 receptor complex
  2. Medvedev, A. E.; Thomas, K.; Awomoyi, A.; Kuhns, D. B.; Gallin, J. I.; Li, X. X.; Vogel, S. N.
  3. Journal of Immunology. 2005, JUN 1; 174(11): 6587-6591.
  1. 11.   Aerosol delivery of glucosylated polyethylenimine/phosphatase and tensin homologue deleted on chromosome 10 complex suppresses Akt downstream pathways in the lung of K-ras null mice
  2. Kim, H. W.; Park, I. K.; Cho, C. S.; Lee, K. H.; Beck, G. R.; Colburn, N. H.; Cho, M. H.
  3. Cancer Research. 2004, NOV 1; 64(21): 7971-7976.
  1. 12.   Synergistic growth of stem cell factor and granulocyte macrophage colony-stimulating factor involves kinase-dependent and -independent contributions from c-Kit
  2. Lennartsson, J.; Shivakrupa, R.; Linnekin, D.
  3. Journal of Biological Chemistry. 2004, OCT 22; 279(43): 44544-44553.
  1. 13.   Contribution of JNK, Mek, Mos and PI-3K signaling to GVBD in Xenopus oocytes
  2. Mood, K.; Bong, Y. S.; Lee, H. S.; Ishimura, A.; Daar, I. O.
  3. Cellular Signalling. 2004, MAY; 16(5): 631-642.
  1. 14.   The soluble sema domain of the RON receptor inhibits macrophage-stimulating protein-induced receptor activation
  2. Angeloni, D.; Danilkovitch-Miagkova, A.; Miagkov, A.; Leonard, E. J.; Lerman, M. I.
  3. Journal of Biological Chemistry. 2004 279(5): 3726-3732.
  1. 15.   Tyrosine phosphorylation of the Janus kinase 2 activation loop is essential for a high-activity catalytic state but dispensable for a basal catalytic state
  2. Chatti, K.; Farrar, W. L.; Duhe, R. J.
  3. Biochemistry. 2004 43(14): 4272-4283.
  1. 16.   Activating mutations in STAT3 and STAT5 differentially affect cellular proliferation and apoptotic resistance in multiple myeloma cells
  2. Hodge, D. R.; Xiao, W. H.; Wang, L. H.; Li, D. P.; Farrar, W. L.
  3. Cancer Biology & Therapy. 2004 3(2): 188-194.
  1. 17.   Ectopic EphA4 receptor induces posterior protrusions via FGF signaling in Xenopus embryos
  2. Park, E. K.; Warner, N.; Bong, Y. S.; Stapleton, D.; Maeda, R.; Pawson, T.; Daar, I. O.
  3. Molecular Biology of the Cell. 2004 15(4): 1647-1655.
  1. 18.   Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation
  2. Haan, S.; Ferguson, P.; Sommer, U.; Hiremath, M.; McVicar, D. W.; Heinrich, P. C.; Johnston, J. A.; Cacalano, N. A.
  3. Journal of Biological Chemistry. 2003 278(34): 31972-31979.
  1. 19.   cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia
  2. Hitzler, J. K.; Witte, D. P.; Jenkins, N. A.; Copeland, N. G.; Gilbert, D. J.; Naeve, C. W.; Look, A. T.; Morris, S. W.
  3. American Journal of Pathology. 1999 155(1): 53-59.
  1. 20.   Differential Control of the Phosphorylation State of Proline-Juxtaposed Serine Residues Ser(725) of Stat5a and Ser(730) of Stat5b in Prolactin-Sensitive Cells
  2. Yamashita, H.; Xu, J.; Erwin, R. A.; Farrar, W. L.; Kirken, R. A.; Rui, H. G.
  3. Journal of Biological Chemistry. 1998 273(46): 30218-30224.
  1. 21.   Determination of Flavopiridol (L86 8275 Nsc 649890) in Human Plasma By Reversed-Phase Liquid Chromatography With Electrochemical Detection
  2. Stinson, S. F.; Hill, K.; Siford, T. J.; Phillips, L. R.; Daw, T. W.
  3. Cancer Chemotherapy and Pharmacology. 1998 42(4): 261-265.
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