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  1. 1.   Effect of Suppressive Oligodeoxynucleotides on the Development of Inflammation-Induced Papillomas
  2. Ikeuchi, H.; Kinjo, T.; Klinman, D. M.
  3. Cancer Prevention Research. 2011, May; 4(5): 752-757.
  1. 2.   A selective small-molecule nuclear factor-kappa B inhibitor from a high-throughput cell-based assay for "activator protein-1 hits"
  2. Kang, M. I.; Henrich, C. J.; Bokesch, H. R.; Gustafson, K. R.; McMahon, J. B.; Baker, A. R.; Young, M. R.; Colburn, N. H.
  3. Molecular Cancer Therapeutics. 2009 8(3): 571-581.
  1. 3.   Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies
  2. Wei, Q.; Jiang, H.; Matthews, C. P.; Colburn, N. H.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2008 105(50): 19738-19743.
  1. 4.   AP-1 a target for cancer prevention
  2. Matthews, C. P.; Colburn, N. H.; Young, M. R.
  3. Current Cancer Drug Targets. 2007, Jun; 7(4): 317-324.
  1. 5.   Fra-1 a target for cancer prevention or intervention
  2. Young, M. R.; Colburn, N. H.
  3. Gene. 2006, Sep; 379: 1-11.
  1. 6.   Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis
  2. Zudaire, E.; Martinez, A.; Garayoa, M.; Pio, R.; Kaur, G.; Woolhiser, M. R.; Metcalfe, D. D.; Hook, W. A.; Siraganian, R. P.; Guise, T. A.; Chirgwin, J. M.; Cuttitta, F.
  3. American Journal of Pathology. 2006, JAN; 168(1): 280-291.
  1. 7.   Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis
  2. Kim, D. J.; Akiyama, T. E.; Harman, F. S.; Burns, A. M.; Shan, W. W.; Ward, J. M.; Kennett, M. J.; Gonzalez, F. J.; Peters, J. M.
  3. Journal of Biological Chemistry. 2004 279(22): 23719-23727.
  1. 8.   Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation
  2. Dhar, A.; Hu, J.; Reeves, R.; Resar, L. M. S.; Colburn, N. H.
  3. Oncogene. 2004 23(25): 4466-4476.
  1. 9.   Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms
  2. Hou, D. X.; Kai, K.; Li, J. J.; Lin, S. G.; Terahara, N.; Wakamatsu, M.; Fujii, M.; Young, M. R.; Colburn, N.
  3. Carcinogenesis. 2004 25(1): 29-36.
  1. 10.   Nitric oxide does not mediate but inhibits transformation and tumor phenotype
  2. Dhar, A.; Brindley, J. M.; Stark, C.; Citro, M. L.; Keefer, L. K.; Colburn, N. H.
  3. Molecular Cancer Therapeutics. 2003 2(12): 1285-1293.
  1. 11.   AP-1, NF kappa B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model
  2. Suzukawa, K.; Weber, T. J.; Colburn, N. H.
  3. Environmental Health Perspectives. 2002 110(9): 865-870.
  1. 12.   Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently
  2. Young, M. R.; Nair, R.; Bucheimer, N.; Tulsian, P.; Brown, N.; Chapp, C.; Hsu, T. C.; Colburn, N. H.
  3. Molecular and Cellular Biology. 2002 22(2): 587-598.
  1. 14.   Decrease in K-ras p21 and increase in Raf1 and activated Erk 1 and 2 in murine lung tumors initiated by N-nitrosodimethylamine and promoted by 2,3,7,8-tetrachlorodibenzo-p-dioxin
  2. Ramakrishna, G.; Perella, C.; Birely, L.; Diwan, B. A.; Fornwald, L. W.; Anderson, L. M.
  3. Toxicology and Applied Pharmacology. 2002 179(1): 21-34.
  1. 15.   Enhancement of N-nitrosodiethylamine-initiated hepatocarcinogenesis by phenytoin in male F344/NCr rats at a dose causing maximal induction of CYP2B
  2. Diwan, B. A.; Henneman, J. R.; Nims, R. W.
  3. International Journal of Toxicology. 2001 20(2): 81-87.
  1. 16.   A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappa B or ODC transactivation
  2. Yang, H. S.; Jansen, A. P.; Nair, R.; Shibahara, K.; Verma, A. K.; Cmarik, J. L.; Colburn, N. H.
  3. Oncogene. 2001 20(6): 669-676.
  1. 17.   Activator protein 1 (AP-1)- and nuclear factor kappa B (NF-kappa B)-dependent transcriptional events in carcinogenesis
  2. Hsu, T. C.; Young, M. R.; Cmarik, J.; Colburn, N. H.
  3. Free Radical Biology and Medicine. 2000 28(9): 1338-1348.
  1. 18.   Difluoromethylornithine chemoprevention of epidermal carcinogenesis in K14-HPV16 transgenic mice
  2. Arbeit, J. M.; Riley, R. R.; Huey, B.; Porter, C.; Kelloff, G.; Lubet, R.; Ward, J. M.; Pinkel, D.
  3. Cancer Research. 1999 59(15): 3610-3620.
  1. 19.   Tumor Promoter Induces High Mobility Group Hmg-Y Protein Expression in Transformation-Sensitive But Not -Resistant Cells
  2. Cmarik, J. L.; Li, Y.; Ogram, S. A.; Min, H. Z.; Reeves, R.; Colburn, N. H.
  3. Oncogene. 1998 16(26): 3387-3396.
  1. 20.   Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation
  2. Watts, R. G.; Huang, C. S.; Young, M. R.; Li, J. J.; Dong, Z. G.; Pennie, W. D.; Colburn, N. H.
  3. Oncogene. 1998 17(26): 3493-3498.
  1. 21.   Tgf-Alpha Sustains Clonal Expansion By Promoter-Dependent, Chemically Initiated Rat Hepatocytes
  2. Kaufmann, W. K.; Byrd, L. L.; Palmieri, D.; Nims, R. W.; Rice, J. M.
  3. Carcinogenesis. 1997 18(7): 1381-1387.
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