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  1. 1.   Genome-scale exon perturbation screens uncover exons critical for cell fitness
  2. Xiao,Meisheng; Damodaran,Arun Prasath; Kumari,Bandana; Dickson, Ethan; Xing, Kun; On, Tyler A; Parab, Nikhil; King, Helen E; Perez, Alexendar R; Guiblet,Wilfried; Duncan,Gerard; Che,Anney; Chari,Raj; Andresson,Thorkell; Vidigal, Joana A; Weatheritt, Robert J; Aregger,Michael; Gonatopoulos Pournatzis,Thomas
  3. Molecular Cell. 2024, Jul 11; 84(13): 2553-2572.
  1. 2.   IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
  2. Bolomsky, Arnold; Ceribelli, Michele; Scheich, Sebastian; Rinaldi, Kristina; Huang, Da Wei; Chakraborty, Papiya; Pham, Lisette; Wright, George W; Hsiao, Tony; Morris, Vivian; Choi, Jaewoo; Phelan, James D; Holewinski,Ronald; Andresson,Thorkell; Wisniewski, Jan; Riley, Deanna; Pittaluga, Stefania; Hill, Elizabeth; Thomas, Craig J; Muppidi, Jagan; Young, Ryan M
  3. Cancer Cell. 2024, Jul 8; 42(7): 1185-1201.
  1. 3.   Ex vivo culture resting time impacts transplantation outcomes of genome-edited human hematopoietic stem and progenitor cells in xenograft mouse models
  2. Demirci, Selami; Khan,Muhammad; Hinojosa, Gabriela; Le, Anh; Leonard, Alexis; Essawi, Khaled; Gudmundsdottir, Bjorg; Liu, Xiong; Zeng, Jing; Inam, Zaina; Chu, Rebecca; Uchida, Naoya; Araki, Daisuke; London, Evan; Butt, Henna; Maitland, Stacy A; Bauer, Daniel E; Wolfe, Scot A; Larochelle, Andre; Tisdale, John F
  3. Cytotherapy. 2024, Jun ; 26(6): 641-648.
  1. 4.   Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer
  2. Furusawa, Takashi; Cavero, Renzo; Liu, Yue; Li, Haojian; Xu,Xia; Andresson,Thorkell; Reinhold, William; White, Olivia; Boufraqech, Myriem; Meyer,Thomas; Hartmann, Oliver; Diefenbacher, Markus E; Pommier, Yves; Weyemi, Urbain
  3. Molecular Carcinogenesis. 2024, Feb 27;
  1. 5.   Protocol for the saturation and multiplexing of genetic variants using CRISPR-Cas9
  2. Sahu,Sounak; Sullivan,Teresa; Southon,Eileen; Caylor,Dylan; Geh, Josephine; Sharan,Shyam
  3. STAR Protocols. 2023, Nov 08; 4(4): 102702.
  1. 6.   The KIR2DL1 intermediate upstream element participates in gene activation
  2. Wright,Paul; Li,Hongchuan; Rahman, Md Ahasanur; Anderson,Erik; Karwan,Megan; Carrell,Jeff; Anderson,Steve
  3. Immunogenetics. 2023, Oct 06;
  1. 7.   An engineered cell line with a hRpn1-attached handle to isolate proteasomes
  2. Negi,Hitendra; Osei Amponsa,Vasty; Ibrahim, Bishoy; Evans, Christine N; Sullenberger, Catherine; Loncarek,Jadranka; Chari,Raj; Walters,Kylie
  3. The Journal of Biological Chemistry. 2023, Jun 22; 104948.
  1. 8.   Reproducibility metrics for context-specific CRISPR screens
  2. Billmann, Maximilian; Ward, Henry N; Aregger,Michael; Costanzo, Michael; Andrews, Brenda J; Boone, Charles; Moffat, Jason; Myers, Chad L
  3. Cell Systems. 2023, May 17; 14(5): 418-422.e2.
  1. 9.   CRISPR-Cas9-AAV versus lentivector transduction for genome modification of X-linked severe combined immunodeficiency hematopoietic stem cells
  2. Brault, Julie; Liu, Taylor; Liu,Siyuan; Lawson, Amanda; Choi, Uimook; Kozhushko, Nikita; Bzhilyanskaya, Vera; Pavel-Dinu, Mara; Meis, Ronald J; Eckhaus, Michael A; Burkett,Sandra; Bosticardo, Marita; Kleinstiver, Benjamin P; Notarangelo, Luigi D; Lazzarotto, Cicera R; Tsai, Shengdar Q; Wu, Xiaolin; Dahl, Gary A; Porteus, Matthew H; Malech, Harry L; De Ravin, Suk See
  3. Frontiers in Immunology. 2023, Jan 4; 13: 1067417.
  1. 10.   CRISPR-Cas9 Genome Editing and Rapid Selection of Cell Pools
  2. Stoyko, Daniel; O, Timothy; Hernandez,Adrianna; Konstantinidou, Parthena; Meng, Qingcai; Haase, Astrid D
  3. Current Protocols. 2022, Dec; 2(12): e624.
  1. 11.   Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity
  2. Long, Erping; Yin, Jinhu; Funderburk, Karen M; Xu, Mai; Feng, James; Kane, Alexander; Zhang, Tongwu; Myers, Timothy; Golden, Alyxandra; Thakur, Rohit; Kong, Hyunkyung; Jessop, Lea; Kim, Eun Young; Jones, Kristine; Chari,Raj; Machiela, Mitchell J; Yu, Kai; Iles, Mark M; Landi, Maria Teresa; Law, Matthew H; Chanock, Stephen J; Brown, Kevin M; Choi, Jiyeon
  3. American Journal of Human Genetics. 2022, Nov 18;
  1. 12.   Context-Dependent Function of Long Noncoding RNA PURPL in Transcriptome Regulation during p53 Activation
  2. Hartford, Corrine Corrina R; Shrestha, Roshan L; Pongor, Lorinc; Zhao,Yongmei; Chen, Xiongfong; Fromont,Caroline; Chaudhary, Ritu; Li, Xiao Ling; Pasterczyk, Katherine R; Kumar, Ravi; Muys, Bruna R; Tsitsipatis, Dimitrios; Chari,Raj; Gorospe, Myriam; Aladjem, Mirit I; Khan, Javed; Basrai, Munira A; Grammatikakis, Ioannis; Lal, Ashish
  3. Molecular and Cellular Biology. 2022, Nov 07; 42(12): e0028922.
  1. 13.   An Evolutionarily Conserved AU-Rich Element in the 3' Untranslated Region of a Transcript Misannotated as a Long Noncoding RNA Regulates RNA Stability
  2. Dangelmaier, Emily A; Li, Xiao Ling; Hartford, Corrine Corrina R; King,Julianna; Zibitt, Meira S; Chari,Raj; Grammatikakis, Ioannis; Lal, Ashish
  3. Molecular and cellular biology. 2022, Mar 10; e0050521.
  1. 14.   Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates
  2. Trofka, Anna; Huang,Bau-Lin; Zhu,Jianjian; Heinz,Will; Magidson,Valentin; Shibata, Yuki; Shi, Yun-Bo; Tarchini, Basile; Stadler, H Scott; Kabangu, Mirindi; Al Haj Baddar, Nour W; Voss, S Randal; Mackem,Susan
  3. Current biology : CB. 2021, Nov 22; 31(22): 4923-4934.e5.
  1. 15.   Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s
  2. Hou, Shurong; Lee, Jeong Min; Myint,Wazo; Matsuo,Hiroshi; Yilmaz, Nese Kurt; Schiffer, Celia A.
  3. Journal of Biological Chemistry. 2021, Aug; 297(2):
  1. 16.   Verification of CRISPR editing and finding transgenic inserts by Xdrop indirect sequence capture followed by short- and long-read sequencing
  2. Blondal, Thorarinn; Gamba, Cristina; Jagd, Lea Moller; Su,Ling; Demirov,Dimiter; Guo,Amber; Johnston, Camille M.; Riising, Eva M.; Wu,Xiaolin; Mikkelsen, Marie J.; Szabova,Ludmila; Mouritzen, Peter
  3. Methods. 2021, Jul; 191: 68-77.
  1. 17.   Genomic tagging of endogenous human ESCRT-I complex preserves ESCRT-mediated membrane-remodeling functions
  2. Hoffman, Huxley K.; Fernandez,Melissa; Groves, Nicholas S.; Freed,Eric; van Engelenburg, Schuyler B.
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2019, Nov 1; 294(44): 16266-16281.
  1. 18.   CRISPR/Cas9-mediated Knockout and In Situ Inversion of ORF57 Gene from All Copies of The KSHV Genome in BCBL-1 Cells
  2. BeltCappellino, Andrew; Majerciak,Vladimir; Lobanov, Alexei; Lack, Justin; Cam, Maggie; Zheng,Zhi-Ming
  3. Journal of virology. 2019, NOV; 93(21): pii: JVI.00628-19..
  1. 19.   Efficient and Precise Genome Editing in Shewanella with Recombineering and CRISPR/Cas9-Mediated Counter-Selection
  2. Corts, Anna D.; Thomason,Lynn; Gill, Ryan T.; Gralnick, Jeffrey A.
  3. ACS SYNTHETIC BIOLOGY. 2019, Aug; 8(8): 1877-1889.
  1. 20.   Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia
  2. Kim, Miriam Y; Yu, Kyung-Rok; Kenderian, Saad S; Ruella, Marco; Chen, Shirley; Shin, Tae-Hoon; Aljanahi, Aisha A; Schreeder, Daniel; Klichinsky, Michael; Shestova, Olga; Kozlowski, Miroslaw S; Cummins, Katherine D; Shan, Xinhe; Shestov, Maksim; Bagg, Adam; Morrissette, Jennifer J D; Sekhri, Palak; Lazzarotto, Cicera R; Calvo, Katherine R; Kuhns, Doug; Donahue, Robert E; Behbehani, Gregory K; Tsai, Shengdar Q; Dunbar, Cynthia E; Gill, Saar
  3. Cell. 2018, May 31; 173(6): 1439-1453.e19.
  1. 21.   Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex
  2. Guo, Tai Wei; Bartesaghi, Alberto; Yang, Hui; Falconieri, Veronica; Rao, Prashant; Merk, Alan; Eng, Edward T; Raczkowski, Ashleigh M; Fox, Tara; Earl, Lesley A; Patel, Dinshaw J; Subramaniam, Sriram
  3. Cell. 2017, Oct 05; 171(2): 414-426.e12.
  1. 22.   Chemical Modification of CRISPR gRNAs Eliminate type I Interferon Responses in Human Peripheral Blood Mononuclear Cells
  2. Schubert, Mollie S; Cedrone, Edward; Neun, Barry; Behlke, Mark A; Dobrovolskaia, Marina
  3. Journal of cytokine biology. 2018 3(1): pii: 121.
  1. 23.   Innovative Technologies for Advancement of WHO Risk Group 4 Pathogens Research
  2. Logue, James; Solomon,Jeffrey; Niemeyer, Brian F.; Benam, Kambez H.; Lin, Aaron E.; Bjornson, Zach; Jiang, Sizun; McIlwain, David R.; Nolan, Garry P.; Palacios, Gustavo; Kuhn, Jens H.
  3. 2019; 437-469.
  1. 24.   A Method to Map Gene Essentiality of Human Pluripotent Stem Cells by Genome-Scale CRISPR Screens with Inducible Cas9
  2. Mair, Barbara; Aregger,Michael; Tong, Amy H Y; Chan, Katherine S K; Moffat, Jason
  3. Methods in molecular biology (Clifton, N.J.). 2022 2377: 1-27.
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