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  1. 1.   The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A
  2. Kochen Rossi, Juan; Nuevo-Tapioles, Cristina; O'Keefe, Rachel A; Hunkeler, Moritz; Schmoker, Anna M; Fissore-O'Leary, Mercedes; Su, Wenjuan; Ahearn, Ian M; Branco, Cristina; Cheong, Hakyung; Esposito,Dom; Clotea, Ioana; Ueberheide, Beatrix; Fischer, Eric S; Philips, Mark R
  3. Cell Reports. 2024, Dec 19; 44(1): 115087.
  1. 2.   Mapping the KRAS Proteoform Landscape in Colorectal Cancer Identifies Truncated KRAS4B that Decreases MAPK Signaling
  2. Adams, Lauren M; Dehart,Caroline; Drown, Bryon S; Anderson, Lissa C; Bocik,William; Boja, Emily S; Hiltke, Tara M; Hendrickson, Christopher L; Rodriguez, Henry; Caldwell, Michael; Vafabakhsh, Reza; Kelleher, Neil L
  3. The Journal of Biological Chemistry. 2022, Dec 02; 299(1): 102768.
  1. 3.   Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR
  2. Yan,Wupeng; Markegard, Evan; Dharmaiah, Srisathiyanarayanan; Urisman, Anatoly; Drew, Matthew; Esposito,Dom; Scheffzek, Klaus; Nissley,Dwight; McCormick, Frank; Simanshu,Dhirendra
  3. Cell reports. 2020, Jul 21; 32(3): 107909.
  1. 4.   RAS internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling
  2. Nelson, Andrew C; Turbyville,Tommy; Dharmaiah,Sathiya; Rigby,Megan; Yang, Rendong; Wang, Ting-You; Columbus,John; Stephens, Robert; Taylor,Troy; Sciacca, Drew; Onsongo, Getiria; Sarver, Anne; Subramanian, Subbaya; Nissley,Dwight; Simanshu,Dhirendra; Lou, Emil
  3. The Journal of biological chemistry. 2020, JUL 10; 295(28): 9335-9348.
  1. 5.   Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer
  2. Sherekar,Mukul; Han, Sae-Won; Ghirlando, Rodolfo; Messing,Simon; Drew,Matt; Rabara,Dana; Waybright,Tim; Juneja, Puneet; O'Neill, Hugh; Stanley, Christopher B; Bhowmik, Debsindhu; Ramanathan, Arvind; Subramaniam,Sriram; Nissley,Dwight; Gillette,Bill; McCormick, Frank; Esposito,Dom
  3. The Journal of biological chemistry. 2020, JAN 24; 295(4): 1105-1119.
  1. 6.   Quantitative biophysical analysis defines key components modulating recruitment of the GTPase KRAS to the plasma membrane
  2. Bindu, Lakshman; Messing, Simon; Schmid, Eva M.; Clogston, Jeffrey; Gillette, Bill; Esposito, Dom; Kessing, Bailey; Fletcher, Daniel A.; Nissley, Dwight; McCormick, Frank; Stephen, Andy; Jean-Francois, Frantz
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2019, Feb 8; 294(6): 2193-2207.
  1. 7.   Control of transcriptional pausing by biased thermal fluctuations on repetitive genomic sequences
  2. Imashimizu, M.; Afek, A.; Takahashi, H.; Lubkowska, Lucyna; Lukatsky, D. B.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2016, Nov 22; 113(47): E7409-E7417.
  1. 8.   The importance of Raf dimerization in cell signaling
  2. Freeman, A. K.; Ritt, D. A.; Morrison, D. K.
  3. Small GTPases. 2013, Jul-Sep; 4(3): 180-5.
  1. 9.   TEM8/ANTXR1 Blockade Inhibits Pathological Angiogenesis and Potentiates Tumoricidal Responses against Multiple Cancer Types
  2. Chaudhary, A.; Hilton, M. B.; Seaman, S.; Haines, D. C.; Stevenson, S.; Lemotte, P. K.; Tschantz, W. R.; Zhang, X. Y. M.; Saha, S.; Fleming, T.; St Croix, B.
  3. Cancer Cell. 2012, Feb; 21(2): 212-226.
  1. 10.   Structural analysis of cytokines comprising the IL-10 family
  2. Zdanov, A.
  3. Cytokine & Growth Factor Reviews. 2010, Oct; 21(5): 325-330.
  1. 11.   Structure of ERA in complex with the 3 ' end of 16S rRNA: Implications for ribosome biogenesis
  2. Tu, C.; Zhou, X. M.; Tropea, J. E.; Austin, B. P.; Waugh, D. S.; Court, D. L.; Ji, X. H.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(35): 14843-14848.
  1. 12.   Structural studies of the interleukin-19 subfamily of cytokines
  2. Zdanov, A.
  3. Interleukins. 2006; 74 : 61-76.
  1. 13.   STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker
  2. Ivanova, A.; Liao, S. Y.; Lerman, M. I.; Ivanov, S.; Stanbridge, E. J.
  3. Journal of Medical Genetics. 2005, JUL; 42(7): 565-576.
  1. 14.   The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase
  2. Marcus, A. I.; Zhou, J.; O'Brate, A.; Hamel, E.; Wong, J.; Nivens, N.; El-Naggar, A.; Yao, T. P.; Khuri, F. R.; Giannakakou, P.
  3. Cancer Research. 2005, MAY 1; 65(9): 3883-3893.
  1. 15.   Human monoclonal antibodies to the S glycoprotein and related proteins as potential therapeutics for SARS
  2. Zhang, M. Y.; Choudhry, V.; Xiao, X. D.; Dimitrov, D. S.
  3. Current Opinion in Molecular Therapeutics. 2005, APR; 7(2): 151-156.
  1. 16.   Classification of ATP-dependent proteases Lon and comparison of the active sites of their proteolytic domains
  2. Rotanova, T. V.; Melnikov, E. E.; Khalatova, A. G.; Makhovskaya, O. V.; Botos, I.; Wlodawer, A.; Gustchina, A.
  3. European Journal of Biochemistry. 2004, DEC; 271(23-24): 4865-4871.
  1. 17.   The SARS-CoV S glycoprotein
  2. Xiao, X.; Dimitrov, D. S.
  3. Cellular and Molecular Life Sciences. 2004, OCT; 61(19-20): 2428-2430.
  1. 18.   Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization
  2. Nikolovska-Coleska, Z.; Wang, R. X.; Fang, X. L.; Pan, H. G.; Tomita, Y.; Li, P.; Roller, P. P.; Krajewski, K.; Saito, N. G.; Stuckey, J. A.; Wang, S. M.
  3. Analytical Biochemistry. 2004, SEP 15; 332(2): 261-273.
  1. 19.   Oligomerization of the SARS-CoV S glycoprotein: dimerization of the N-terminus and trimerization of the ectodomain
  2. Xiao, X. D.; Feng, Y.; Chakraborti, S.; Dimitrov, D. S.
  3. Biochemical and Biophysical Research Communications. 2004, SEP 10; 322(1): 93-99.
  1. 20.   A model of the ACE2 structure and function as a SARS-CoV receptor
  2. Prabakaran, P.; Mao, X. D.; Dimitrov, D. S.
  3. Biochemical and Biophysical Research Communications. 2004 314(1): 235-241.
  1. 21.   Structural features of the interleukin-10 family of cytokines
  2. Zdanov, A.
  3. Current Pharmaceutical Design. 2004 10(31): 3873-3884.
  1. 22.   Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XLAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database
  2. Nikolovska-Coleska, Z.; Xu, L.; Hu, Z. J.; Tomita, Y.; Li, P.; Roller, P. P.; Wang, R. X.; Fang, X. L.; Guo, R. B.; Zhang, M. C.; Lippman, M. E.; Yang, D. J.; Wang, S. M.
  3. Journal of Medicinal Chemistry. 2004 47(10): 2430-2440.
  1. 23.   Crystallization of cyclase-associated protein from Dictyostelium discoideum
  2. Hofmann, A.; Hess, S.; Noegel, A. A.; Schleicher, M.; Wlodawer, A.
  3. Acta Crystallographica Section D-Biological Crystallography. 2002 58(Part 10, Sp. Iss. 2): 1858-1861.
  1. 24.   DNA repair protein levels vis-a-vis anticancer drug resistance in the human tumor cell lines of the National Cancer Institute drug screening program
  2. Xu, Z. Y.; Chen, Z. P.; Malapetsa, A.; Alaoui-Jamali, M.; Bergeron, J.; Monks, A.; Myers, T. G.; Mohr, G.; Sausville, E. A.; Scudiero, D. A.; Aloyz, R.; Panasci, L. C.
  3. Anti-Cancer Drugs. 2002 13(5): 511-519.
  1. 25.   Evolution of the regulators of G-protein signaling multigene family in mouse and human
  2. Sierra, D. A.; Gilbert, D. J.; Householder, D.; Grishin, N. V.; Yu, K.; Ukidwe, P.; Barker, S. A.; He, W.; Wensel, T. G.; Otero, G.; Brown, G.; Copeland, N. G.; Jenkins, N. A.; Wilkie, T. M.
  3. Genomics. 2002 79(2): 177-185.
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