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  1. 1.   AI-driven drug repurposing and binding pose meta dynamics identifies novel targets for monkeypox virus
  2. Patel,Chiragkumar; Mall, Raghvendra; Bensmail, Halima
  3. Journal of Infection and Public Health. 2023, Mar 15; 16(5): 799-807.
  1. 2.   Suppressive oligodeoxynucleotides containing TTAGGG motifs Inhibit cGAS activation in human monocytes
  2. Steinhagen, Folkert; Zillinger, Thomas; Peukert, Konrad; Fox, Mario; Thudium, Marcus; Barchet, Winfried; Putensen, Christian; Klinman, Dennis; Latz, Eicke; Bode, Christian
  3. European journal of immunology. 2018, Apr; 48(4): 605-611.
  1. 3.   The "Connection" Between HIV Drug Resistance and RNase H
  2. Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Pathak, V. K.
  3. Viruses-Basel. 2010, Jul; 2(7): 1476-1503.
  1. 4.   C-terminal Domain Modulates the Nucleic Acid Chaperone Activity of Human T-cell Leukemia Virus Type 1 Nucleocapsid Protein via an Electrostatic Mechanism
  2. Qualley, D. F.; Stewart-Maynard, K. M.; Wang, F.; Mitra, M.; Gorelick, R. J.; Rouzina, I.; Williams, M. C.; Musier-Forsyth, K.
  3. Journal of Biological Chemistry. 2010, Jan; 285(1): 295-307.
  1. 5.   Structure of HIV-1 Reverse Transcriptase with the Inhibitor beta-Thujaplicinol Bound at the RNase H Active Site
  2. Himmel, D. M.; Maegley, K. A.; Pauly, T. A.; Bauman, J. D.; Das, K.; Dharia, C.; Clark, A. D.; Ryan, K.; Hickey, M. J.; Love, R. A.; Hughes, S. H.; Bergqvist, S.; Arnold, E.
  3. Structure. 2009 17(12): 1625-1635.
  1. 6.   Identifying and Characterizing a Functional HIV-1 Reverse Transcriptase-binding Site on Integrase
  2. Wilkinson, T. A.; Januszyk, K.; Phillips, M. L.; Tekeste, S. S.; Zhang, M.; Miller, J. T.; Le Grice, S.; Clubb, R. T.; Chow, S. A.
  3. Journal of Biological Chemistry. 2009 284(12): 7931-7936.
  1. 7.   Mutations in human immunodeficiency virus type 1 RNase H primer grip enhance 3-Azido-3'-deoxythymidine resistance
  2. Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Barr, R.; Pathak, V. K.
  3. Journal of Virology. 2007, Jul; 81(13): 6837-6845.
  1. 8.   Mutations in the U5 sequences adjacent to the primer binding site do not affect tRNA cleavage by Rous sarcoma virus RNase H but do cause aberrant integrations in vivo
  2. Oh, J.; Chang, K. W.; Hughes, S. H.
  3. Journal of Virology. 2006, JAN; 80(1): 451-459.
  1. 9.   Crystal structures for HIV-1 reverse transcriptase in complexes with three pyridinone derivatives: A new class of non-nucleoside inhibitors effective against a broad range of drug-resistant strains
  2. Himmel, D. M.; Das, K.; Clark, A. D.; Hughes, S. H.; Benjahad, A.; Oumouch, S.; Guillemont, J.; Coupa, S.; Poncelet, A.; Csoka, I.; Meyer, C.; Andries, K.; Nguyen, C. H.; Grierson, D. S.; Arnold, E.
  3. Journal of Medicinal Chemistry. 2005, DEC 1; 48(24): 7582-7591.
  1. 10.   Crystallography and the design of anti-AIDS drugs: Conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors
  2. Das, K.; Lewi, P. J.; Hughes, S. H.; Arnold, E.
  3. Progress in Biophysics and Molecular Biology. 2005, JUN; 88(2): 209-231.
  1. 11.   Fixed conformation nucleoside analogs effectively inhibit excision-proficient HIV-1 reverse transcriptases
  2. Boyer, P. L.; Julias, J. G.; Marquez, V. E.; Hughes, S. H.
  3. Journal of Molecular Biology. 2005, JAN 21; 345(3): 441-450.
  1. 12.   Taking aim at a moving target: designing drugs to inhibit drug-resistant HIV-1 reverse transcriptases
  2. Sarafianos, S. G.; Das, K.; Hughes, S. H.; Arnold, E.
  3. Current Opinion in Structural Biology. 2004, DEC; 14(6): 716-730.
  1. 13.   Integration target site selection for retroviruses and transposable elements
  2. Wu, X.; Burgess, S. M.
  3. Cellular and Molecular Life Sciences. 2004, OCT; 61(19-20): 2588-2596.
  1. 14.   Infectious transmission and replication of human T-cell leukemia virus type 1
  2. Derse, D.; Heidecker, G.; Mitchell, M.; Hill, S.; Lloyd, P.; Princler, G.
  3. Frontiers in Bioscience. 2004, SEP 1; 9: 2495-2499.
  1. 15.   Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA
  2. Peletskaya, E. N.; Kogon, A. A.; Tuske, S.; Arnold, E.; Hughes, S. H.
  3. Journal of Virology. 2004 78(7): 3387-3397.
  1. 16.   Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
  2. Tuske, S.; Sarafianos, S. G.; Clark, A. D.; Ding, J. P.; Naeger, L. K.; White, K. L.; Miller, M. D.; Gibbs, C. S.; Boyer, P. L.; Clark, P.; Wang, G.; Gaffney, B. L.; Jones, R. A.; Jerina, D. M.; Hughes, S. H.; Arnold, E.
  3. Nature Structural & Molecular Biology. 2004 11(5): 469-474.
  1. 17.   Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome
  2. Yu, Q.; Konig, R.; Pillai, S.; Chiles, K.; Kearney, M.; Palmer, S.; Richman, D.; Coffin, J. M.; Landau, N. R.
  3. Nature Structural & Molecular Biology. 2004 11(5): 435-442.
  1. 18.   Trapping HIV-1 reverse transcriptase before and after translocation on DNA
  2. Sarafianos, S. G.; Clark, A. D.; Tuske, S.; Squire, C. J.; Das, K.; Sheng, D. Q.; Ilankumaran, P.; Ramesha, A. R.; Kroth, H.; Sayer, J. M.; Jerina, D. M.; Boyer, P. L.; Hughes, S. H.; Arnold, E.
  3. Journal of Biological Chemistry. 2003 278(18): 16280-16288.
  1. 19.   Combinatorial evolution of high-affinity peptides that bind to the Thomsen-Friedenreich carcinoma antigen
  2. Landon, L. A.; Peletskaya, E. N.; Glinsky, V. V.; Karasseva, N.; Quinn, T. P.; Deutscher, S. L.
  3. Journal of Protein Chemistry. 2003 22(2): 193-204.
  1. 20.   Structures of HIV-1 reverse transcriptase with pre- and post- translocation AZTMP-terminated DNA
  2. Sarafianos, S. G.; Clark, A. D.; Das, K.; Tuske, S.; Birktoft, J. J.; Ilankumaran, P.; Ramesha, A. R.; Sayer, J. M.; Jerina, D. M.; Boyer, P. L.; Hughes, S. H.; Arnold, E.
  3. Embo Journal. 2002 21(23): 6614-6624.
  1. 21.   Mutation of the catalytic domain of the foamy virus reverse transcriptase leads to loss of processivity and infectivity
  2. Rinke, C. S.; Boyer, P. L.; Sullivan, M. D.; Hughes, S. H.; Linial, M. L.
  3. Journal of Virology. 2002 76(15): 7560-7570.
  1. 22.   Mutations in the RNase H domain of HIV-1 reverse transcriptase affect the initiation of DNA synthesis and the specificity of RNase H cleavage in vivo
  2. Julias, J. G.; McWilliams, M. J.; Sarafianos, S. G.; Arnold, E.; Hughes, S. H.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2002 99(14): 9515-9520.
  1. 23.   Y586F mutation in murine leukemia virus reverse transcriptase decreases fidelity of DNA synthesis in regions associated with adenine-thymine tracts
  2. Zhang, W. H.; Svarovskaia, E. S.; Barr, R.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2002 99(15): 10090-10095.
  1. 24.   Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA : DNA
  2. Sarafianos, S. G.; Das, K.; Tantillo, C.; Clark, A. D.; Ding, J.; Whitcomb, J. M.; Boyer, P. L.; Hughes, S. H.; Arnold, E.
  3. Embo Journal. 2001 20(6): 1449-1461.
  1. 25.   The Lys103Asn mutation of HIV-1 RT: A novel mechanism of drug resistance
  2. Hsiou, Y.; Ding, J. P.; Das, K.; Clark, A. D.; Boyer, P. L.; Lewi, P.; Janssen, P. A. J.; Kleim, J. P.; Rosner, M.; Hughes, S. H.; Arnold, E.
  3. Journal of Molecular Biology. 2001 309(2): 437-445.
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