Selective Bibliography of Dr. Raj Chari
Laboratory Animal Sciences Program, NCI

"Harnessing genome editing technologies to understand cancer biology with high precision"
Tuesday, January 19, 2021

1. Gooden AA, Evans CN, Sheets TP, Clapp ME, Chari R
dbGuide: a database of functionally validated guide RNAs for genome editing in human and mouse cells
Nucleic Acids Research 49 (D1):D871-D876 Jan 8 2021

2.  Osei-Amponsa V, Sridharan V, Tandon M, Evans CN, Klarmann K, Cheng KT, Lack J, Chari R, Walters KJ
Impact of Losing hRpn13 Pru or UCHL5 on Proteasome Clearance of Ubiquitinated Proteins and RA190 Cytotoxicity
Molecular & Cellular Biology 40 (18):Aug 28 2020

3.  Buel GR, Chen X, Chari R, O'Neill MJ, Ebelle DL, Jenkins C, Sridharan V, Tarasov SG, Tarasova NI, Andresson T, Walters KJ
Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10
Nature Communications 11:1291 Mar 10 2020

4.  Chari R, Church GM
Beyond editing to writing large genomes
Nature Reviews Genetics 18 (12):749-760 Dec 2017

5.  Chari R, Yeo NC, Chavez A, Church GM
sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity
ACS Synthetic Biology 6 (5):902-904 May 19 2017

6.  Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJK, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G
Comparison of Cas9 activators in multiple species
Nature Methods 13 (7):563-567 Jul 2016

7.  Kiani S, Chavez A, Tuttle M, Hal RN, Chari R, Ter-Ovanesyan D, Qian J, Pruitt BW, Beal J, Vora S, Buchthal J, Kowal EJK, Ebrahimkhani MR, Collins JJ, Weiss R, Church G
Cas9 gRNA engineering for genome editing, activation and repression
Nature Methods 12 (11):1051-1054 Nov 2015

8.  Chari R, Mali P, Moosburner M, Church GM
Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach
Nature Methods 12 (9):823-826 Sep 2015

9.  Yang LH, Grishin D, Wang G, Aach J, Zhang CZ, Chari R, Homsy J, Cai XY, Zhao Y, Fan JB, Seidman C, Seidman J, Pu W, Church G
Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells
Nature Communications 5:5507 Nov 26 2014

10.  Briggs AW, Rios X, Chari R, Yang LH, Zhang F, Mali P, Church GM
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers
Nucleic Acids Research 40 (15):e117 Aug 2012






Date Last Updated: 1/8/2021