Sharing Tools and Resources (STAR)

Frederick National Laboratory for Cancer Research

Research Collaboration Page

The National Cancer Institute at Frederick (NCI-F) and Frederick National Laboratory (FNL) is home to many talented scientific researchers. The STAR page at the Scientific Library is dedicated to them, and to the scientific resources they have created, and is open to all NCI-F researchers who wish to share the resources they have developed with the rest of NCI-F, as well as with a larger, world-wide community of researchers, in the spirit of collaboration that moves research forward and makes breakthroughs more likely to happen. Please contact the Scientific Library for more information on how you can have your resource represented on the STAR page.

We invite all STAR participants to link back to this webpage from their resource to encourage ease of access to all these valuable resources.

Current Research Initiatives:

AVIA-Automated Variation and Impact Analysis – AVIA is a web based resource for variant detection (Sanger Sequencing) as well as impact analysis. This resource allows users to interrogate specific genomic coordinates and determine the impact of the mutation based on public information as well as user specified data from their own experiments. Article

bioDBnet-biological DataBase network – bioDBnet is an application integrating a wide range of biological databases and providing an easy interface for researchers to annotate and convert between various biological identifiers like genes to pathways, mouse genes to human genes, SNPs to genes. Article

CyloFold – CyloFold addresses the single-sequence RNA structure prediction problem with pseudoknots. Article

DAVID Bioinformatics Resource – DAVID (the Database for Annotation, Visualization and Integrated Discovery) is a free online bioinformatics resource aimed to provide functional interpretation of large lists of genes derived from genomic studies, e.g. microarray and proteomics studies. Article

KNetFold – KNetFold is the method of choice for RNA secondary structure prediction if an alignment of RNA sequences is available.

NanoFolder – NanoFolder predicts the RNA secondary structure of a set of RNA strands (possibly forming a complex). Article

NCI @ NIH Fellows and Young Investigators (NCI FYI) Mobile App – The NCI FYI mobile application offers a centralized source of available resources to fellows and trainees working on the NIH main Campus in Bethesda, MD, off campus in the surrounding area in Rockville, MD and Frederick, MD.

NCI @ NIH Summer Interns Program (NCI SIP) Mobile App – The NCI SIP mobile application provides summer interns a source for accessing activities and resources available during their eight week tenure working at the NIH main campus in Bethesda, MD, off campus in the surrounding area in Rockville, MD and Frederick, MD.

NCI CADD Group's Chemical Structure Web Services – Web services allowing you to (a) find chemical structures and information about where these molecules occur in the ~140 small molecule databases aggregated by the NCI CADD Group into a collection of approx. 120 million chemical structure records representing about approx. 70 million unique chemical structures, (b) convert your chemical structures from one format into another, and (c) integrate these resources into your own web site.

NCI at Frederick Scientific Publications Database (formerly NCI at Frederick-in-Print) – The NCI at Frederick-in-Print database is a collection of citations for publications authored by employees and contractors of the National Cancer Institute at Frederick from 1997 through the present.

Nitric Oxide Database – See also "Tools for studying the Biological Effects of Nitric Oxide (NO) and Nitroxyl (HNO)".

non-B DB, a database of predicted non-B DNA-forming motifs in mammalian genomes and the non-B DNA Motif Search Tool (nBMST) – non-B DB web resource allows users to query pre-computed non-B DNA motifs in several mammalian species and to submit their favorite DNA sequences for custom non-B DNA search. Article 1Article 2

PHL Immunohistochemistry Database – The PHL Immunohistochemistry Database provides users access to current immunohistochemical techniques organized by antibody target, manufacturer, and fixative.

RNA2D3D – RNA2D3D is a graphical, interactive system for rapid conversion of RNA 2D structures to 3D models and interactive 3D model refinement. Article

StructureLab – StructureLab is a software workbench for prediction and analysis of 2D RNA structures. It provides interactive GUI-based data mining of the solution spaces produced by the secondary structure prediction programs. Article

Tools for Studying the Biological Effects of Nitric Oxide (NO) and Nitroxyl (HNO) – Caged nitric oxide (NO) prodrugs as research tools and for use in designing advances in clinical practice.