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Resistance to HIV-1 infection among highly exposed sex workers in Nairobi: what mediates protection and why does it develop?

  1. Author:
    Plummer, F. A.
    Ball, T. B.
    Kimani, J.
    Fowke, K. R.
  2. Author Address

    Plummer FA Univ Nairobi, Dept Med Microbiol POB 19676 Nairobi Kenya Univ Nairobi, Dept Med Microbiol Nairobi Kenya Univ Manitoba, Dept Med Microbiol & Med Winnipeg MB R3E 0W3 Canada NCI, Expt Immunol Branch, Lab Genom Divers Frederick, MD 21701 USA
    1. Year: 1999
  1. Journal: Immunology Letters
    1. 66
    2. 1-3
    3. Pages: 27-34
  2. Type of Article: Article
  1. Abstract:

    Variability in susceptibility to infection and disease caused by infectious agents is a characteristic of all populations. Among susceptible individuals exposed to an infection: not all become infected and among infected individuals, not all develop disease. It seems logical that variability in susceptibility to infection and disease would apply to infection and disease with human immunodeficiency viruses. However, until recently, it has been generally held that there is no natural immunity to HIV-1 and that once infected, all individuals would ultimately succumb to AIDS. (C) 1999 Elsevier Science B.V. All rights reserved. [References: 47]

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