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Attenuation of Myeloid-Specific TGF beta Signaling Induces Inflammatory Cerebrovascular Disease and Stroke

  1. Author:
    Hollander, M. Christine
    Latour, Lawrence L.
    Yang, Dan
    Ishii, Hiroki
    Xiao, Zhiguang
    Min, Yongfen
    Ray-Choudhury, Abhik
    Munasinghe, Jeeva
    Merchant, Anand
    Lin, Charles
    Hallenbeck, John
    Boehm, Manfred
    Yang, Li
  2. Author Address

    NCI, Lab Canc Biol & Genet, NIH, Bethesda, MD 20892 USA.NINDS, Clin Stroke Cause & Dev, NIH, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA.NHLBI, Ctr Mol Med, NIH, Bldg 10, Bethesda, MD 20892 USA.NINDS, Neuropathol, NIH, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA.NCI, Bioinformat, Ctr Canc Res, NIH, Bethesda, MD 20892 USA.NCI, Canc & Inflammat Program, Ctr Canc Res, NIH, Frederick, MD 21701 USA.
    1. Year: 2017
    2. Date: Dec 8
  1. Journal: Circulation Research
  2. LIPPINCOTT WILLIAMS & WILKINS,
    1. 121
    2. 12
    3. Pages: 1360-1369
  3. Type of Article: Article
  4. ISSN: 0009-7330
  1. Abstract:

    Rationale: Cryptogenic strokes, those of unknown cause, have been estimated as high as 30% to 40% of strokes. Inflammation has been suggested as a critical etiologic factor. However, there is lack of experimental evidence.

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External Sources

  1. DOI: 10.1161/CIRCRESAHA.116.310349
  2. PMID: 29051340
  3. PMCID: PMC5722661
  4. WOS: 000417295400050

Library Notes

  1. Fiscal Year: FY2017-2018
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