Skip NavigationSkip to Content
Return Return to Search Results

Manipulating chemoattractant and receptor genes

  1. Author:
    Le, Y. Y.
    Cui, Y. H.
    Iribarren, P.
    Ying, G. G.
    Wang, J. M.

  2. Author Address

    NCI, Mol Immunoregulat Lab, Ctr Canc Res, Frederick, MD 21702 USA NCI, Mol Immunoregulat Lab, Ctr Canc Res, Frederick, MD 21702 USA Wang JM NCI, Mol Immunoregulat Lab, Ctr Canc Res, Frederick, MD 21702 USA
    1. Year: 2002
  2. Journal: In Vivo
    1. 16
    2. 1
    3. Pages: 1-23
  4. Type of Article: Review
  1. Abstract:

    Chemoattractants, including classical chemotactic factors and members of the chemokine superfamily, function as inducers of leukocyte trafficking and activation based on interactions with seven transmembrane (STM), G protein-coupled receptors. These molecules are expressed by many cell types either constitutively or upon stimulation. Considerable knowledge about the pathophysiological role of chemoattractants and their receptors has been accumulated during the past two decades. However; recent studies using transgenic and gene targeting technology have provided a better illustration of the importance and complexity of the involvement of chemoattractants and receptors in leukocyte trafficking, inflammation, infection, immune responses, development, angiogenesis/angiostasis, and malignant tumors.

    See More

  1. Keywords:

External Sources

  1. No sources found.

Library Notes

  1. No notes added.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel