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The cell biology of HIV-I and other retroviruses

  1. Author:
    Freed, E. O.
    Moul, A. J.
  2. Author Address

    McGill Univ, HIV1 RNA Trafficking Lab, Lady Davis Inst Med Res, Sir Mortimer B Davis Jewish Gen Hosp,Dept Med, Montreal, PQ H3T 1E2, Canada. NCI, Virus Cell Interact Sect, HIV Drug Resistance Program, Frederick, MD 21702 USA. McGill Univ, HIV1 RNA Trafficking Lab, Lady Davis Inst Med Res,Dept Microbiol, Sir Mortimer B Davis Jewish Gen Hosp, Montreal, PQ H3T 1E2, Canada. McGill Univ, HIV1 RNA Trafficking Lab, Lady Davis Inst Med Res,Dept Immunol, Sir Mortimer B Davis Jewish Gen Hosp, Montreal, PQ H3T 1E2, Canada.;Freed, EO, McGill Univ, HIV1 RNA Trafficking Lab, Lady Davis Inst Med Res, Sir Mortimer B Davis Jewish Gen Hosp,Dept Med, Montreal, PQ H3T 1E2, Canada.;efreed@nih.gov andrew.mouland@McGill.ca
    1. Year: 2006
    2. Date: Nov
  1. Journal: Retrovirology
    1. 3
  2. Type of Article: Review
  3. Article Number: 77
  4. ISSN: 1742-4690
  1. Abstract:

    In recognition of the growing influence of cell biology in retrovirus research, we recently organized a Summer conference sponsored by the American Society for Cell Biology (ASCB) on the Cell Biology of HIV-1 and other Retroviruses (July20-23, 2006, Emory University, Atlanta, Georgia). The meeting brought together a number of leading investigators interested in the interplay between cell biology and retrovirology with an emphasis on presentation of new and unpublished data. The conference was arranged from early to late events in the virus replication cycle, with sessions on viral fusion, entry, and transmission; post-entry restrictions to retroviral infection; nuclear import and integration; gene expression/regulation of retroviral Gag and genomic RNA; and assembly/release. In this review, we will attempt to touch briefly on some of the highlights of the conference, and will emphasize themes and trends that emerged at the meeting. Meeting report: The conference began with a keynote address from W. Sundquist on the biochemistry of HIV-1 budding. This presentation will be described in the section on Assembly and Release of Retroviruses.

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External Sources

  1. DOI: 10.1186/1742-4690-3-77
  2. WOS: 000242645400001

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