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  1. 1.   Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties
  2. Rai, Ganesha; Urban, Daniel J.; Mott, Bryan T.; Hu, Xin; Yang, Shyh-Ming; Benavides, Gloria A.; Johnson, Michelle S.; Squadrito, Giuseppe L.; Brimacombe, Kyle R.; Lee, Tobie D.; Cheff, Dorian M.; Zhu, Hu; Henderson, Mark J.; Pohida, Katherine; Sulikowski, Gary A.; Dranow, David M.; Kabir, Md; Shah, Pranav; Padilha, Elias; Tao, Dingyin; Fang, Yuhong; Christov, Plamen P.; Kim, Kwangho; Jana, Somnath; Muttil, Pavan; Anderson, Tamara; Kunda, Nitesh K.; Hathaway, Helen J.; Kusewitt, Donna F.; Oshima, Nobu; Cherukuri, Murali; Davies, Douglas R.; Norenberg, Jeffrey P.; Sklar, Larry A.; Moore, William J.; Dang, Chi; Stott,Gordon; Neckers, Leonard; Flint,Andrew; Darley-Usmar, Victor M.; Simeonov, Anton; Waterson, Alex G.; Jadhav, Ajit; Hall, Matthew D.; Maloney, David J.
  3. JOURNAL OF MEDICINAL CHEMISTRY. 2020, OCT 8; 63(19): 10984-11011.
  1. 2.   NO and hepatocellular cancer
  2. Wang, Ronghua; Geller, David A.; Wink,David; Cheng, Bin; Billiar, Timothy R.
  3. British journal of pharmacology. 2019, Dec 11;
  1. 3.   Opposing Effects of Pigment Epithelium-Derived Factor on Breast Cancer Cell versus Neuronal Survival: Implication for Brain Metastasis and Metastasis-Induced Brain Damage
  2. Fitzgerald, D. P.; Subramanian, P.; Deshpande, M.; Graves, C.; Gordon, I.; Qian, Y. Z.; Snitkovsky, Y.; Liewehr, D. J.; Steinberg, S. M.; Paltan-Ortiz, J. D.; Herman, M. M.; Camphausen, K.; Palmieri, D.; Becerra, S. P.; Steeg, P. S.
  3. Cancer Research. 2012, Jan; 72(1): 144-153.
  1. 4.   Variation in innate immunity genes and risk of multiple myeloma
  2. Purdue, M. P.; Lan, Q.; Menashe, I.; Zheng, T. Z.; Zhang, Y. W.; Yeager, M.; Hosgood, H. D.; Zahm, S. H.; Chanock, S. J.; Rothman, N.; Baris, D.
  3. Hematological Oncology. 2011, Mar; 29(1): 42-46.
  1. 5.   Down-Regulation of miR-101 in Endothelial Cells Promotes Blood Vessel Formation through Reduced Repression of EZH2
  2. Smits, M.; Mir, S. E.; Nilsson, R. J. A.; van der Stoop, P. M.; Niers, J. M.; Marquez, V. E.; Cloos, J.; Breakefield, X. O.; Krichevsky, A. M.; Noske, D. P.; Tannous, B. A.; Wurdinger, T.
  3. Plos One. 2011, Jan; 6(1): 11.
  1. 6.   Insulin-like growth factor 1 receptor antibody induces rhabdomyosarcoma cell death via a process involving AKT and Bcl-x(L)
  2. Mayeenuddin, L. H.; Yu, Y.; Kang, Z.; Helman, L. J.; Cao, L.
  3. Oncogene. 2010, Dec; 29(48): 6367-6377.
  1. 7.   Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia
  2. Liu, X.; Ryl, L.; Yang, J.; Liao, A. J.; Aliaga, C.; Watts, R.; Tan, S. F.; Kaiser, J.; Shanmugavelandy, S. S.; Rogers, A.; Loughran, K.; Petersen, B.; Yuen, J.; Meng, F. X.; Baab, K. T.; Jarbadan, N. R.; Broeg, K.; Zhang, R. R.; Liao, J. S.; Sayers, T. J.; Kester, M.; Loughran, T. P.
  3. Blood. 2010, Nov; 116(20): 4192-4201.
  1. 8.   Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1 alpha Expression in an AhR-Independent Fashion
  2. Terzuoli, E.; Puppo, M.; Rapisarda, A.; Uranchimeg, B.; Cao, L. A.; Burger, A. M.; Ziche, M.; Melillo, G.
  3. Cancer Research. 2010, Sep 1; 70(17): 6837-6848.
  1. 9.   Identification and characterization of a novel agonistic anti-DR4 human monoclonal antibody
  2. Feng, Y.; Xiao, X. D.; Zhu, Z. Y.; Dimitrov, D. S.
  3. Mabs. 2010, Sep-Oct; 2(5): 565-570.
  1. 10.   Differential involvement of vascular endothelial growth factor in the survival of hypoxic colon cancer cells
  2. Calvani, M.; Trisciuoglio, D.; Bergamaschi, C.; Shoemaker, R. H.; Melillo, G.
  3. Cancer Research. 2008 68(1): 285-291.
  1. 11.   Monoclonal antibodies against components of the IGF system for cancer treatment
  2. Feng, Y.; Dimitrov, D. S.
  3. Current Opinion in Drug Discovery & Development. 2008 11(2): 178-185.
  1. 12.   EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1
  2. Thomas, S. L.; Zhong, D. S.; Zhou, W.; Malik, S.; Liotta, D.; Snyder, J. P.; Hamel, E.; Giannakakou, P.
  3. Cell Cycle. 2008 7(15): 2409-2417.
  1. 13.   UVC inhibits HIF-1 alpha protein translation by a DNA damage- and topoisomerase I-independent pathway
  2. Rapisarda, A.; Melillo, G.
  3. Oncogene. 2007, Oct; 26(48): 6875-6884.
  1. 14.   Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival
  2. Bian, X. W.; Yang, S. X.; Chen, L. H.; Ping, Y. F.; Zhou, X. D.; Wang, Q. L.; Jiang, X. F.; Gong, W. H.; Xiao, H. L.; Du, L. L.; Chen, Z. Q.; Zhao, W.; Shi, L. Q.; Wang, J. M.
  3. Neurosurgery. 2007, Sep; 61(3): 570-578.
  1. 15.   The anti-cancer compound Nordy inhibits CXCR4-mediated production of IL-8 and VEGF by malignant human glioma cells
  2. Ping, Y. F.; Yao, X. H.; Chen, J. H.; Liu, H.; Chen, D. L.; Zhou, X. D.; Wang, J. M.; Bian, X. W.
  3. Journal of Neuro-Oncology. 2007, Aug; 84(1): 21-29.
  1. 16.   Pharmacokinetics, pharmacodynamics and drug metabolism - Characterization of in vitro and in vivo metabolic pathways of the investigational anticancer agent, 2-methoxyestradiol
  2. Lakhani, N. J.; Sparreboom, A.; Xu, X.; Veenstra, T. D.; Venitz, J.; Dahut, W. L.; Figg, W. D.
  3. Journal of Pharmaceutical Sciences. 2007, Jul; 96(7): 1821-1831.
  1. 17.   Endogenous IL-12 triggers an antiangiogenic program in melanoma cells
  2. Airoldi, I.; Di Carlo, E.; Cocco, C.; Taverniti, G.; D'Antuono, T.; Ognio, E.; Watanabe, M.; Ribatti, D.; Pistoia, V.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2007, Mar; 104(10): 3996-4001.
  1. 18.   Hypoxia-inducible factor 1 inhibitors
  2. Melillo, G.
  3. Oxygen Biology and Hypoxia. 2007; 435 : 385-402.
  1. 19.   Inhibiting hypoxia-inducible factor 1 for cancer therapy
  2. Melillo, G.
  3. Molecular Cancer Research. 2006, Sep; 4(9): 601-605.
  1. 20.   Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
  2. Kim, B. G.; Li, C. L.; Qiao, W. H.; Mamura, M.; Kasperczak, B.; Anver, M.; Wolfraim, L.; Hong, S.; Mushinski, E.; Potter, M.; Kim, S. J.; Fu, X. Y.; Deng, C. X.; Letterio, J. J.
  3. Nature. 2006, Jun; 441(7096): 1015-1019.
  1. 21.   Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors
  2. Nanda, A.; Karim, B.; Peng, Z. S.; Liu, G. S.; Qiu, W. P.; Gan, C.; Vogelstein, B.; St Croix, B.; Kinzler, K. W.; Huso, D. L.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, FEB 28; 103(9): 3351-3356.
  1. 22.   Novel human monoclonal antibodies to insulin-like growth factor (IGH)-II that potently inhibit the IGF receptor type I signal transduction function
  2. Feng, Y.; Zhu, Z. Y.; Xiao, X. D.; Choudhry, V.; Barrett, J. C.; Dimitrov, D. S.
  3. Molecular Cancer Therapeutics. 2006, JAN; 5(1): 114-120.
  1. 23.   Topotecan inhibits HIF-1 alpha, but not HIF-2 alpha, protein accumulation and tumor growth in human renal cancer cells
  2. Rapisarda, A.; Uranchimeg, B.; Hollingshead, M.; Borgel, S.; Carter, J.; Shoemaker, R. H.; Melillo, G.
  3. Clinical Cancer Research. 2005, DEC 15; 11(24, Part 2 Suppl. S): 9019S-9019S.
  1. 24.   Provision of granulocyte-macrophage colony-stimulating factor converts an autoimmune response to a self-antigen into an antitumor response
  2. Ji, Q. Y.; Gondek, D.; Hurwitz, A. A.
  3. Journal of Immunology. 2005, AUG 1; 175(3): 1456-1463.
  1. 25.   Effect of EBV LMP1 targeted DNAzymes on cell proliferation and apoptosis
  2. Lu, Z. X.; Ye, M.; Yan, G. R.; Li, Q.; Tang, M.; Lee, L. M.; Sun, L. Q.; Cao, Y.
  3. Cancer Gene Therapy. 2005, JUL; 12(7): 647-654.
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