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  1. 1.   Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance
  2. Zhang,Wengang; Bradburn, Devin; Heidebrink, Gretchen; Liu, Yonglan; Jang,Hyunbum; Nussinov,Ruth; Kõivomägi, Mardo
  3. Journal of Molecular Biology. 2025, Mar 31; 169121.
  1. 2.   Slower CDK4 and faster CDK2 activation in the cell cycle
  2. Zhang,Wengang; Liu,Yonglan; Jang,Hyunbum; Nussinov,Ruth
  3. Structure (London, England : 1993). 2024, Apr 23;
  1. 3.   Survival of Head and Neck Cancer Cells Relies upon LZK Kinase-Mediated Stabilization of Mutant p53
  2. Edwards, Zoe C.; Trotter, Eleanor W.; Torres-Ayuso, Pedro; Chapman, Phil; Wood, Henry M.; Nyswaner, Katherine; Brognard, John
  3. Cancer Research. 2017, Sep 15; 77(18): 4961-4972.
  1. 4.   NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction
  2. Juhasz, Agnes; Markel, Susan; Gaur, Shikha; Liu, Han; Lu, Jiamo; Jiang, Guojian; Wu, Xiwei; Antony, Smitha; Wu, Yongzhong; Melillo, Giovanni; Meitzler, Jennifer L; Haines, Diana; Butcher, Donna; Roy, Krishnendu; Doroshow, James H
  3. Journal of Biological Chemistry. 2017, May 12; 292(19): 7866-7887.
  1. 5.   RB inactivation in keratin 18 positive thymic epithelial cells promotes non-cell autonomous T cell hyperproliferation in genetically engineered mice
  2. Song, Yurong; Sullivan, Teresa; Klarmann, Kimberly; Gilbert, Debra; O'Sullivan, Theresa; Lu, Lucy; Wang, Sophie; Haines, Diana; Van Dyke, Terry; Keller, Jonathan
  3. PLOS ONE. 2017, Feb 3; 12(2): e0171510.
  1. 6.   DNA Methyltransferase Inhibitor, Zebularine, Delays Tumor Growth and Induces Apoptosis in a Genetically Engineered Mouse Model of Breast Cancer
  2. Chen, M.; Shabashvili, D.; Nawab, A.; Yang, S. X.; Dyer, L. M.; Brown, K. D.; Hollingshead, M.; Hunter, K. W.; Kaye, F. J.; Hochwald, S. N.; Marquez, V. E.; Steeg, P.; Zajac-Kaye, M.
  3. Molecular Cancer Therapeutics. 2012, Feb; 11(2): 370-382.
  1. 7.   Matrix-assisted laser desorption/ionization mass spectrometry reveals decreased calcylcin expression in small cell lung cancer
  2. Lee, H. S.; Park, J. W.; Chertov, O.; Colantonio, S.; Simpson, J. T.; Fivash, M. J.; Yoo, C. W.; Lee, G. K.; Zo, J. I.; Kim, H. T.; Kim, H. K.
  3. Pathology International. 2012, Jan; 62(1): 28-35.
  1. 8.   Identification of a Src Tyrosine Kinase/SIAH2 E3 Ubiquitin Ligase Pathway That Regulates C/EBP delta Expression and Contributes to Transformation of Breast Tumor Cells
  2. Sarkar, T. R.; Sharan, S.; Wang, J.; Pawar, S. A.; Cantwell, C. A.; Johnson, P. F.; Morrison, D. K.; Wang, J. M.; Sterneck, E.
  3. Molecular and Cellular Biology. 2012, Jan; 32(2): 320-332.
  1. 9.   Structure and function of RapA: A bacterial Swi2/Snf2 protein required for RNA polymerase recycling in transcription
  2. Jin, D. J.; Zhou, Y. N.; Shaw, G.; Ji, X. H.
  3. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms. 2011, Sep; 1809(9): 470-475.
  1. 10.   JS-K; a nitric oxide-releasing prodrug, modulates beta-catenin/TCF signaling in leukemic Jurkat cells: Evidence of an S-nitrosylated mechanism
  2. Nath, N.; Chattopadhyay, M.; Pospishi, L.; Cieciura, L. Z.; Goswami, S.; Kodela, R.; Saavedra, J. E.; Keefer, L. K.; Kashfi, K.
  3. Biochemical Pharmacology. 2010, Dec; 80(11): 1641-1649.
  1. 11.   Plant Natural Products in Anticancer Drug Discovery
  2. Grothaus, P. G.; Cragg, G. M.; Newman, D. J.
  3. Current Organic Chemistry. 2010, Oct; 14(16): 1781-1791.
  1. 12.   Substituted E-3-(3-Indolylmethylene)-1,3-dihydroindo1-2-ones with Antitumor Activity. In Depth Study of the Effect on Growth of Breast Cancer Cells
  2. Andreani, A.; Bellini, S.; Burnelli, S.; Granaiola, M.; Leoni, A.; Locatelli, A.; Morigi, R.; Rambaldi, M.; Varoli, L.; Calonghi, N.; Cappadone, C.; Zini, M.; Stefanelli, C.; Masotti, L.; Shoemaker, R. H.
  3. Journal of Medicinal Chemistry. 2010, Aug; 53(15): 5567-5575.
  1. 13.   Natural product scaffolds as leads-to drugs
  2. Newman, D. J.; Cragg, G. M.
  3. Future Medicinal Chemistry. 2009, Nov; 1(8): 1415-1427.
  1. 14.   A dual role of Cdk2 in DNA damage response
  2. Satyanarayana, A.; Kaldis, P.
  3. Cell Division. 2009, May; 4: 4.
  1. 15.   Cdk2 plays a critical role in hepatocyte cell cycle progression and survival in the setting of cyclin D1 expression in vivo
  2. Hanse, E. A.; Nelsen, C. J.; Goggin, M. M.; Anttila, C. K.; Mullany, L. K.; Berthet, C.; Kaldis, P.; Crary, G. S.; Kuriyama, R.; Albrecht, J. H.
  3. Cell Cycle. 2009 8(17): 2802-2809.
  1. 16.   Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G(1)/S transition
  2. Li, W.; Kotoshiba, S.; Berthet, C.; Hilton, M. B.; Kaldis, P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(2): 486-491.
  1. 17.   Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
  2. Satyanarayana, A.; Kaldis, P.
  3. Oncogene. 2009 28(33): 2925-2939.
  1. 18.   Id1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivo
  2. Suh, H. C.; Leeanansaksiri, W.; Ji, M.; Klarmann, K. D.; Renn, K.; Gooya, J.; Smith, D.; McNiece, I.; Lugthart, S.; Valk, P. J.; Delwel, R.; Keller, J. R.
  3. Oncogene. 2008, Sep 18; 27(42): 5612-5623.
  1. 19.   Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2
  2. Satyanarayana, A.; Berthet, C.; Lopez-Molina, J.; Coppola, V.; Tessarollo, L.; Kaldis, P.
  3. Development. 2008 135(20): 3389-3400.
  1. 20.   p21 inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint
  2. Satyanarayana, A.; Hilton, M. B.; Kaldis, P.
  3. Molecular Biology of the Cell. 2008 19(1): 65-77.
  1. 21.   Cell-specific responses to loss of cyclin-dependent kinases
  2. Berthet, C.; Kaldis, P.
  3. Oncogene. 2007, Jul; 26(31): 4469-4477.
  1. 22.   Structure and interactions of the first three RNA recognition motifs of splicing factor Prp24
  2. Bae, E.; Reiter, N. J.; Bingman, C. A.; Kwan, S. S.; Lee, D.; Phillips, G. N.; Butcher, S. E.; Brow, D. A.
  3. Journal of Molecular Biology. 2007, Apr; 367(5): 1447-1458.
  1. 23.   Importance of the 5 S rRNA-binding ribosomal proteins for cell viability and translation in Escherichia coli
  2. Korepanov, A. P.; Gongadze, G. M.; Garber, M. B.; Court, D. L.; Bubunenko, M. G.
  3. Journal of Molecular Biology. 2007, Mar; 366(4): 1199-1208.
  1. 24.   15-deoxy-Delta(12,14)-prostaglandin J(2) inhibits transcriptional activity of estrogen receptor-alpha via covalent modification of DNA-binding domain
  2. Kim, H. J.; Kim, J. Y.; Meng, Z. J.; Wang, L. H.; Liu, F.; Conrads, T. P.; Burke, T. R.; Veenstra, T. D.; Farrar, W. L.
  3. Cancer Research. 2007, Mar; 67(6): 2595-2602.
  1. 25.   Kinase-independent function of cyclin E
  2. Geng, Y.; Lee, Y. M.; Welcker, M.; Swanger, J.; Zagozdzon, A.; Winer, J. D.; Roberts, J. M.; Kaldis, P.; Clurman, B. E.; Sicinski, P.
  3. Molecular Cell. 2007, Jan; 25(1): 127-139.
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