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  1. 1.   Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine
  2. Kaur, Gurmeet; Evans, David M.; Teicher, Beverly A.; Coussens,Nathan
  3. SLAS Discovery. 2021, Nov 12;
  1. 2.   Specific RITA modification produces hyperselective cytotoxicity while maintaining in vivo antitumor efficacy
  2. Peyser,Brian; Hermone,Ann; Salamoun, Joseph M; Burnett, James C; Hollingshead,Melinda; McGrath,Connor; Gussio,Rick; Wipf, Peter
  3. Molecular cancer therapeutics. 2019, OCT; 18(10): 1765-1774.
  1. 3.   Overexpression of IL-38 protein in anticancer drug-induced lung injury and acute exacerbation of idiopathic pulmonary fibrosis
  2. Tominaga, Masaki; Okamoto, Masaki; Kawayama, Tomotaka; Matsuoka, Masanobu; Kaieda, Shinjiro; Sakazaki, Yuki; Kinoshita, Takashi; Mori, Daisuke; Inoue, Akira; Hoshino, Tomoaki
  3. Respiratory Investigation. 2017, Sep; 55(5): 293-299.
  1. 4.   Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-p-activated nitric oxide donor PABA/NO in malignant gliomas
  2. Kogias, E.; Osterberg, N.; Baumer, B.; Psarras, N.; Koentges, C.; Papazoglou, A.; Saavedra, J. E.; Keefer, L. K.; Weyerbrock, A.
  3. International Journal of Cancer. 2012, Mar; 130(5): 1184-1194.
  1. 5.   CEBPD Reverses RB/E2F1-Mediated Gene Repression and Participates in HMDB-Induced Apoptosis of Cancer Cells
  2. Pan, Y. C.; Li, C. F.; Ko, C. Y.; Pan, M. H.; Chen, P. J.; Tseng, J. T.; Wu, W. C.; Chang, W. C.; Huang, A. M.; Sterneck, E.; Wang, J. M.
  3. Clinical Cancer Research. 2010, Dec; 16(23): 5770-5780.
  1. 6.   Elucidation of the Molecular Mechanisms of a Salicylhydrazide Class of Compounds by Proteomic Analysis
  2. Cao, X. F.; Plasencia, C.; Kanzaki, A.; Yang, A.; Burke, T. R.; Neamati, N.
  3. Current Cancer Drug Targets. 2009 9(2): 189-201.
  1. 7.   Botryllamides: Natural Product Inhibitors of ABCG2
  2. Henrich, C. J.; Robey, R. W.; Takada, K.; Bokesch, H. R.; Bates, S. E.; Shukla, S.; Ambudkar, S. V.; McMahon, J. B.; Gustafson, K. R.
  3. Acs Chemical Biology. 2009 4(8): 637-647.
  1. 8.   DNA fingerprinting of the NCI-60 cell line panel
  2. Lorenzi, P. L.; Reinhold, W. C.; Varma, S.; Hutchinson, A. A.; Pommier, Y.; Chanock, S. J.; Weinstein, J. N.
  3. Molecular Cancer Therapeutics. 2009 8(4): 713-724.
  1. 9.   Expression of 25 human ABC transporters in the yeast Pichia pastoris and characterization of the purified ABCC3 ATPase activity
  2. Chloupkova, M.; Pickert, A.; Lee, J. Y.; Souza, S.; Trinh, Y. T.; Connelly, S. M.; Dumont, M. E.; Dean, M.; Urbatsch, I. L.
  3. Biochemistry. 2007, Jul; 46(27): 7992-8003.
  1. 10.   Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study
  2. Shankavaram, U. T.; Reinhold, W. C.; Nishizuka, S.; Major, S.; Morita, D.; Chary, K. K.; Reimers, M. A.; Scherf, U.; Kahn, A.; Dolginow, D.; Cossman, J.; Kaldjian, E. P.; Scudiero, D. A.; Petricoin, E.; Liotta, L.; Lee, J. K.; Weinstein, J. N.
  3. Molecular Cancer Therapeutics. 2007, Mar; 6(3): 820-832.
  1. 11.   Crinamine from Crinum asiaticum var.japonicum inhibits hypoxia inducible factor-1 activity but not activity of hypoxia inducible factor-2
  2. Kim, Y. H.; Park, E. J.; Park, M. H.; Badarch, U.; Woldemichael, G. M.; Beutler, J. A.
  3. Biological & Pharmaceutical Bulletin. 2006, Oct; 29(10): 2140-2142.
  1. 12.   Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt
  2. Gills, J. J.; Holbeck, S.; Hollingshead, M.; Hewitt, S. M.; Kozikowski, A. P.; Dennis, P. A.
  3. Molecular Cancer Therapeutics. 2006, Mar; 5(3): 713-722.
  1. 13.   Novel human monoclonal antibodies to insulin-like growth factor (IGH)-II that potently inhibit the IGF receptor type I signal transduction function
  2. Feng, Y.; Zhu, Z. Y.; Xiao, X. D.; Choudhry, V.; Barrett, J. C.; Dimitrov, D. S.
  3. Molecular Cancer Therapeutics. 2006, JAN; 5(1): 114-120.
  1. 14.   Drugs aimed at targeting characteristic karyotypic phenotypes of cancer cells
  2. Wallqvist, A.; Huang, R.; Covell, D. G.; Roschke, A. V.; Gelhaus, K. S.; Kirsch, I. R.
  3. Molecular Cancer Therapeutics. 2005, OCT; 4(10): 1559-1568.
  1. 15.   Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics
  2. Sun, H. Y.; Nikolovska-Coleska, Z.; Chen, J. Y.; Yang, C. Y.; Tomita, Y.; Pan, H. G.; Yoshioka, Y.; Krajewski, K.; Roller, P. P.; Wang, S. M.
  3. Bioorganic & Medicinal Chemistry Letters. 2005, FEB 1; 15(3): 793-797.
  1. 16.   Cytotoxicity of RH1: NAD(P)H : quinone acceptor oxidoreductase (NQO1)-independent oxidative stress and apoptosis induction
  2. Tudor, G.; Alley, M.; Nelson, C. M.; Huang, R. L.; Covell, D. G.; Gutierrez, P.; Sausville, E. A.
  3. Anti-Cancer Drugs. 2005 16(4): 381-391.
  1. 17.   Linking pathway gene expressions to the growth inhibition response from the National Cancer Institute's anticancer screen and drug mechanism of action
  2. Huang, R.; Wallqvist, A.; Thanki, N.; Covell, D. G.
  3. Pharmacogenomics Journal. 2005 5(6): 381-399.
  1. 18.   Anticancer metal compounds in NCI's tumor-screening database: putative mode of action
  2. Huang, R. L.; Wallqvist, A.; Covell, D. G.
  3. Biochemical Pharmacology. 2005 69(7): 1009-1039.
  1. 19.   Fluorinated 2-(4-amino-3-methylphenyl) benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells
  2. Brantley, E.; Trapani, V.; Alley, M. C.; Hose, C. D.; Bradshaw, T. D.; Stevens, M. F. G.; Sausville, E. A.; Stinson, S. F.
  3. Drug Metabolism and Disposition. 2004, DEC; 32(12): 1392-1401.
  1. 20.   Components of the cell death machine and drug sensitivity of the National Cancer Institute cell line panel
  2. Svingen, P. A.; Loegering, D.; Rodriquez, J.; Meng, X. W.; Mesner, P. W.; Holbeck, S.; Monks, A.; Krajewski, S.; Scudiero, D. A.; Sausville, E. A.; Reed, J. C.; Lazebnik, Y. A.; Kaufmann, S. H.
  3. Clinical Cancer Research. 2004, OCT 15; 10(20): 6807-6820.
  1. 21.   Getting back on track, or what to do when apoptosis is de-railed - Recoupling oncogenes to the apoptotic machinery
  2. Fearnhead, H. O.
  3. Cancer Biology & Therapy. 2004 3(1): 21-28.
  1. 22.   Small molecule toxins targeting tumor receptors
  2. Dyba, M.; Tarasova, N. I.; Michejda, C. J.
  3. Current Pharmaceutical Design. 2004 10(19): 2311-2334.
  1. 23.   The hollow fibre model in cancer drug screening: the NCI experience
  2. Decker, S.; Hollingshead, M.; Bonomi, C. A.; Carter, J. P.; Sausville, E. A.
  3. European Journal of Cancer. 2004 40(6): 821-826.
  1. 24.   Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XLAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database
  2. Nikolovska-Coleska, Z.; Xu, L.; Hu, Z. J.; Tomita, Y.; Li, P.; Roller, P. P.; Wang, R. X.; Fang, X. L.; Guo, R. B.; Zhang, M. C.; Lippman, M. E.; Yang, D. J.; Wang, S. M.
  3. Journal of Medicinal Chemistry. 2004 47(10): 2430-2440.
  1. 25.   Aryl hydrocarbon receptor activation of an antitumor aminoflavone: Basis of selective toxicity for MCF-7 breast tumor cells
  2. Loaiza-Perez, A. I.; Kenney, S.; Boswell, J.; Hollingshead, M.; Alley, M. C.; Hose, C.; Ciolino, H. P.; Yeh, G. C.; Trepel, J. B.; Vistica, D. T.; Sausville, E. A.
  3. Molecular Cancer Therapeutics. 2004 3(6): 715-725.
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