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  1. 1.   Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential
  2. Fermaintt, Charles S.; Peramuna, Thilini; Cai, Shengxin; Takahashi-Ruiz, Leila; Essif, Jacob Nathaniel; Grant, Corena V.; O'Keefe,Barry; Mooberry, Susan L.; Cichewicz, Robert H.; Risinger, April L.
  3. Cancers. 2021, JUN; 13(11):
  1. 2.   Diacylglycerol Kinase Malfunction in Human Disease and the Search for Specific Inhibitors
  2. Merida, Isabel; Arranz-Nicolás, Javier; Torres-Ayuso,Pedro; Ávila-Flores, Antonia
  3. Handbook of experimental pharmacology. 2019, Jun 22;
  1. 3.   Protein kinase Ca gain-of-function variant in Alzheimer's disease displays enhanced catalysis by a mechanism that evades down-regulation
  2. Callender, Julia A; Yang, Yimin; Lordén, Gema; Stephenson, Natalie L; Jones, Alexander C; Brognard, John; Newton, Alexandra C
  3. Proceedings of the National Academy of Sciences of the United States of America. 2018, Jun 12; 115(24): E5497-E5505.
  1. 4.   Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity.
  2. Czikora, Agnes; Lundberg, Daniel J; Abramovitz, Adelle; Lewin, Nancy E; Kedei, Noemi; Peach, Megan L; Zhou, Xiaoling; Merritt, Raymond C; Craft, Elizabeth A; Braun, Derek C; Blumberg, Peter M
  3. The Journal of biological chemistry. 2016, May 20; 291(21): 11133-47.
  1. 5.   Serine-phosphorylated STAT1 is a prosurvival factor in Wilms' tumor pathogenesis
  2. Timofeeva, O. A.; Plisov, S.; Evseev, A. A.; Peng, S.; Jose-Kampfner, M.; Lovvorn, H. N.; Dome, J. S.; Perantoni, A. O.
  3. Oncogene. 2006, Dec; 25(58): 7555-7564.
  1. 6.   Actin is the primary cellular receptor of bistramide A
  2. Statsuk, A. V.; Bai, R. L.; Baryza, J. L.; Verma, V. A.; Hamel, E.; Wender, P. A.; Kozmin, S. A.
  3. Nature Chemical Biology. 2005, DEC; 1(7): 383-388.
  1. 7.   Evidence for the involvement of tyrosine kinase ZAP 70 in nuclear retinoid receptor-dependent transactivation in T lymphocytes
  2. Ishaq, M.; DeGray, G.; Natarajan, V.
  3. Journal of Biological Chemistry. 2005, OCT 7; 280(40): 34152-34158.
  1. 8.   Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells
  2. Sun, R. H.; Gao, P.; Chen, L.; Ma, D. L.; Wang, J. M.; Oppenheim, J. J.; Zhang, N.
  3. Cancer Research. 2005, FEB 15; 65(4): 1433-1441.
  1. 9.   Protein kinase C alpha-mediated chemotaxis of neutrophils requires NF-kappa B activity but is independent of TNF alpha signaling in mouse skin in vivo
  2. Cataisson, C.; Pearson, A. J.; Torgerson, S.; Nedospasov, S. A.; Yuspa, S. H.
  3. Journal of Immunology. 2005, FEB 1; 174(3): 1686-1692.
  1. 10.   A proinflarnmatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1
  2. Zhang, N.; Inan, S.; Cowan, A.; Sun, R. H.; Wang, J. M.; Rogers, T. J.; Caterina, M.; Oppenheim, J. J.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005 102(12): 4536-4541.
  1. 11.   Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C)
  2. Tamamura, H.; Sigano, D. M.; Lewin, N. E.; Peach, M. L.; Nicklaus, M. C.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2004, SEP 23; 47(20): 4858-4864.
  1. 12.   The discovery of protein kinase C (PK-C) isozyme: Specific ligands driven by a solid-phase combinatorial synthesis of diacylglycerol-lactones (DAG-lactones)
  2. Duan, D. H.; Peach, M. L.; Lai, C. C.; Lewin, N. E.; Kelley, J. A.; Blumberg, P. M.; Marquez, V. E.
  3. Abstracts of Papers of the American Chemical Society. 2004, AUG 22; 228(Part 1): 177-MEDI, Abstract U939-177-MEDI, Abstract U939.
  1. 13.   Hydrophobic ligand-protein interactions vs. ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C)
  2. Sigano, D. M.; Tamamura, H.; Lewin, N. E.; Peach, M. L.; Nicklaus, M. C.; Blumberg, P. M.; Marquez, V. E.
  3. Abstracts of Papers of the American Chemical Society. 2004, AUG 22; 228(Part 1): 229-MEDI, Abstract U949-229-MEDI, Abstract U949.
  1. 14.   Combinatorial synthesis, quality control and biological evaluation of diacylglycerol (DAG)-lactone libraries - Protein kinase C (PKC)-isozyme-specific ligands
  2. Duan, D.; Lai, C. C.; Kelley, J. A.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E.
  3. Abstracts of Papers of the American Chemical Society. 2004, MAR 28; 227(033-MEDI, Part 2): U10-U10.
  1. 15.   Conformationally constrained diacylglycerol (DAG) analogs: 4-C-hydroxyethyl-5-O-acyl-2,3-dideoxy-D-glyceropentono-1,4-lactone analogs as protein kinase C (PKC) ligands
  2. Lee, J.; Kim, S. Y.; Kang, J. H.; Acs, G.; Acs, P.; Blumberg, P. M.; Marquez, V. E.
  3. European Journal of Medicinal Chemistry. 2004 39(1): 69-77.
  1. 16.   Conformationally constrained analogues of diacylglycerol. 20. The search for an elusive binding site on protein kinase C through relocation of the carbonyl pharmacophore along the sn-1 side chain of 1,2-diacylglycerol lactones
  2. Tamamura, H.; Sigano, D. M.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2004 47(3): 644-655.
  1. 17.   Conformationally constrained analogues of diacylglycerol. 21. A solid-phase method of synthesis of diacylglycerol lactones as a prelude to a combinatorial approach for the synthesis of protein kinase C isozyme-specific ligands
  2. Duan, D. H.; Lewin, N. E.; Sigano, D. M.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2004 47(12): 3248-3254.
  1. 18.   Solid phase synthesis of diacylglycerol-lactones(DAG-lactones) in macrokans as a prelude to the synthesis of protein kinase c (PKC) isozyme-specific ligands by a combinatorial approach
  2. Duan, D. H.
  3. Abstracts of Papers of the American Chemical Society. 2003 225(Part 2): U304-U304.
  1. 19.   Protein kinase C delta plays opposite roles in growth mediated by wild type Kit and an oncogenic Kit mutant
  2. Jelacic, T. M.; Linnekin, D. M.
  3. Blood. 2003 102(11, Part 1): 834A-834A.
  1. 20.   Comparative modeling of C1 regulatory domains in the protein kinase C isozyme family
  2. Peach, M. L.; Nicklaus, M. C.; Blumberg, P. M.; Marquez, V. E.
  3. Abstracts of Papers of the American Chemical Society. 2003 225(Part 1): U761-U761.
  1. 21.   Conformationally constrained analogues of diacylglycerol (DAG). Part 19: Asymmetric syntheses of (3R)- and (3S)-3-hydroxy-4,4- disubstituted heptono-1,4-lactones as protein kinase C (PK-C) ligands with increased hydrophilicity
  2. Nacro, K.; Lee, J.; Barchi, J. J.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E.
  3. Tetrahedron. 2002 58(26): 5335-5345.
  1. 22.   Glutathione-S-transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase
  2. Villafania, A.; Anwar, K.; Amar, S.; Chie, L.; Way, D.; Chung, D. L.; Adler, V.; Ronai, Z.; Brandt-Rauf, P. W.; Yamaizumii, Z.; Kung, H. F.; Pincus, M. R.
  3. Annals of Clinical and Laboratory Science. 2000 30(1): 57-64.
  1. 23.   Tumor promoter benzoyl peroxide induces sulfhydryl oxidation in protein kinase C: Its reversibility is related to the cellular resistance to peroxide-induced cytotoxicity
  2. Gopalakrishna, R.; Gundimeda, U.; Anderson, W. B.; Colburn, N. H.; Slaga, T. J.
  3. Archives of Biochemistry and Biophysics. 1999 363(2): 246-258.
  1. 24.   Mutual Dependence of Jun-N-Terminal Kinase and Protein Kinase C On the Oncogenic Ras-P21 Protein-Induced Mitogenic Signalling Pathway
  2. Chung, D.; Villafania, A.; Anwar, K.; Amar, S.; Rijhwani, K.; Kung, H. F.; Adler, V.; Ronai, Z.; Brandtrauf, P.; Yamaizumi, Z.; Pincus, M. R.
  3. Medical Science Research. 1998 26(3): 147-150.
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