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EML Services

The Electron Microscopy Laboratory (EML) offers a variety of core services.  To order services, please submit an electronic request via CSAS; or to discuss the project scope and design, please contact Dr. Ulrich Baxa.   For additional information on how to use the on-line accession system please click here.  EML services include preparation and shipment of sample fixative, sample processing, embedding, sectioning, staining and imaging.  The EML has a number of resources and protocols that may also be helpful.

Research Need

Technique

Instrument

+++ = Best 

++ = Good

+ = Poor

- = Not Available

Please see EML services and technology development for
more information on techniques.

SEM
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TEM
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Surface Analysis of cells and soft matter nanoparticles 

Surface Analysis of cells and soft matter nanoparticles
Processing and metal coating for SEM 

Energy dispersive x-ray spectroscopy

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Description: Surface Imaging of large biological objects and materials 

Surface Imaging of large biological objects and materials
Variable pressure SEM with cooling stage

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Description: Virus Particle Analysis 

Virus Particle Analysis
Plastic embedding/ thin section TEM 

Negative staining

Cryo-EM

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-

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Description: Elemental Analysis 

Elemental Analysis
Energy dispersive x-ray spectroscopy 

Selected Area Electron Diffraction

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Description: Ultrastructure (Subcellular/Organelles) 

Ultrastructure
(Subcellular/Organelles)
Plastic embedding/ thin section TEM

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Description: Protein complexes and isolated organelles 

Protein complexes and isolated organelles
Negative staining 

Plastic embedding/ thin section TEM

Cryo-electron microscopy

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Description: Nanoparticle Analysis 

Nanoparticle Analysis
Drop cast on appropriate film 

Energy dispersive x-ray spectroscopy

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Description: Soft Matter Nanoparticle Analysis 

Soft Matter Nanoparticle Analysis
Cryo-EM 

Negative staining

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-

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Description: Nanoparticles in Cells or TissuesF 

Nanoparticles in Cells or Tissues
Plastic embedding/ thin section TEM 

Energy dispersive x-ray spectroscopy

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Description: 3-Dimensional Analysis of cellular ultrastructure or nanoparticles 

3-Dimensional Analysis of cellular ultrastructure or nanoparticles
Electron tomography from thin plastic sections 

Electron tomography from cryo-EM specimens

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Immuno Electron Microscopy

Description: Immuno Electron Microscopy 1Description: Immuno Electron Microscopy 2

Pre-embedding immunolabeling 

Post-embedding immunolabeling

Immuno-labeling followed by negative staining

Immuno-labeling followed by SEM

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Description: Custom Project 

Custom Project
Please contact us about customized protocols or how to process and image unique samples.

Page last updated March 26, 2014 @ 2:05 pm